Development and Characterization of a Scaffold-Free 3D Spheroid Model of Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes

Tissue Engineering - Part C: Methods

Volumn 21, Issue 8, 2015, Pages 852-861

  Beauchamp, Philippe ^a   Moritz, Wolfgang ^b   Kelm, Jens M ^b   Ullrich, Nina D ^c,d   Agarkova, Irina ^b   Anson, Blake D ^e   Suter, Thomas M ^a   Zuppinger, Christian ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b InSphero AG   (Switzerland)

^c UNIVERSITY OF BERN   (Switzerland)

^d UNIVERSITY OF HEIDELBERG   (Germany)

^e Cellular Dynamics International   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3D MODELING; CALCIUM; CELL CULTURE; CELL DEATH; DROPS; FLUORESCENCE; HEART; MAMMALS; MOTION TRACKING; PROTEINS; STEM CELLS;

CALCIUM TRANSIENTS; DIFFERENTIATED CELLS; ELECTRICAL STIMULATIONS; HOMOGENEOUS TISSUES; IMMUNOFLUORESCENCE MICROSCOPY; INDUCED PLURIPOTENT STEM CELLS; OPTICAL MOTION TRACKING; THREE-DIMENSIONAL CULTURE;

SCAFFOLDS (BIOLOGY);

ALPHA SMOOTH MUSCLE ACTIN; DESMIN; HEAT SHOCK PROTEIN 70; MYOMESIN; MYOSIN HEAVY CHAIN BETA; PROTEIN TYROSINE KINASE; SODIUM CALCIUM EXCHANGE PROTEIN; CONNEXIN 43;

ARTICLE; CONTROLLED STUDY; EXTRACELLULAR CALCIUM; GENE EXPRESSION; HEART MUSCLE CELL; HEART RATE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MUSCLE FIBRIL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; TISSUE SCAFFOLD; TISSUE STRUCTURE; ADULT; BIOLOGICAL MODEL; CALCIUM SIGNALING; CARDIAC MUSCLE CELL; CHEMISTRY; CYTOLOGY; INDUCED PLURIPOTENT STEM CELL; METABOLISM; MULTICELLULAR SPHEROID;

RODENTIA;

ADULT; CALCIUM SIGNALING; CONNEXIN 43; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MODELS, CARDIOVASCULAR; MYOCYTES, CARDIAC; SPHEROIDS, CELLULAR; TISSUE SCAFFOLDS;

EID: 84929601516     PISSN: 19373384     EISSN: 19373392     Source Type: Journal    
DOI: 10.1089/ten.tec.2014.0376     Document Type: Article

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