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Volumn 302, Issue 10, 2012, Pages

Functional scaffold-free 3-D cardiac microtissues: A novel model for the investigation of heart cells

Author keywords

Fibroblasts; Myocytes; Optical mapping; Three dimensional culture model

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); BARIUM ION; CALCIUM ION; GREEN FLUORESCENT PROTEIN; INWARDLY RECTIFYING POTASSIUM CHANNEL;

EID: 84861157366     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00743.2011     Document Type: Article
Times cited : (85)

References (59)
  • 1
    • 0042358985 scopus 로고    scopus 로고
    • Cell culture: Biology's new dimension
    • Abbott A. Cell culture: biology's new dimension. Nature 424: 870-872, 2003.
    • (2003) Nature , vol.424 , pp. 870-872
    • Abbott, A.1
  • 2
    • 0033047458 scopus 로고    scopus 로고
    • Cardiac organogenesis in vitro: Reestablishment of three-dimensional tissue architecture by dissociated neonatal rat ventricular cells
    • Akins RE, Boyce RA, Madonna ML, Schroedl NA, Gonda SR, McLaughlin TA, Hartzell CR. Cardiac organogenesis in vitro: reestablishment of three-dimensional tissue architecture by dissociated neonatal rat ventricular cells. Tissue Eng 5: 103-118, 1999.
    • (1999) Tissue Eng , vol.5 , pp. 103-118
    • Akins, R.E.1    Boyce, R.A.2    Madonna, M.L.3    Schroedl, N.A.4    Gonda, S.R.5    McLaughlin, T.A.6    Hartzell, C.R.7
  • 4
  • 5
    • 0033505795 scopus 로고    scopus 로고
    • Why is left ventricular hypertrophy so predictive of morbidity and mortality?
    • Benjamin EJ, Levy D. Why is left ventricular hypertrophy so predictive of morbidity and mortality? Am J Med Sci 317: 168-175, 1999.
    • (1999) Am J Med Sci , vol.317 , pp. 168-175
    • Benjamin, E.J.1    Levy, D.2
  • 6
    • 34547916003 scopus 로고    scopus 로고
    • Novel anisotropic engineered cardiac tissues: Studies of electrical propagation
    • Bursac N, Loo Y, Leong K, Tung L. Novel anisotropic engineered cardiac tissues: studies of electrical propagation. Biochem Biophys Res Commun 361: 847-853, 2007.
    • (2007) Biochem Biophys Res Commun , vol.361 , pp. 847-853
    • Bursac, N.1    Loo, Y.2    Leong, K.3    Tung, L.4
  • 7
    • 0344584377 scopus 로고    scopus 로고
    • Cultivation in rotating bioreactors promotes maintenance of cardiac myocyte electrophysiology and molecular properties
    • Bursac N, Papadaki M, White JA, Eisenberg SR, Vunjak-Novakovic G, Freed LE. Cultivation in rotating bioreactors promotes maintenance of cardiac myocyte electrophysiology and molecular properties. Tissue Eng 9: 1243-1253, 2003.
    • (2003) Tissue Eng , vol.9 , pp. 1243-1253
    • Bursac, N.1    Papadaki, M.2    White, J.A.3    Eisenberg, S.R.4    Vunjak-Novakovic, G.5    Freed, L.E.6
  • 8
    • 11144346203 scopus 로고    scopus 로고
    • Structural and functional characterisation of cardiac fibroblasts
    • Camelliti P, Borg TK, Kohl P. Structural and functional characterisation of cardiac fibroblasts. Cardiovasc Res 65: 40-51, 2005.
    • (2005) Cardiovasc Res , vol.65 , pp. 40-51
    • Camelliti, P.1    Borg, T.K.2    Kohl, P.3
  • 9
    • 1842507518 scopus 로고    scopus 로고
    • Fibroblast network in rabbit sinoatrial node: Structural and functional identification of homogeneous and heterogeneous cell coupling
    • Camelliti P, Green CR, LeGrice I, Kohl P. Fibroblast network in rabbit sinoatrial node: structural and functional identification of homogeneous and heterogeneous cell coupling. Circ Res 94: 828-835, 2004.
    • (2004) Circ Res , vol.94 , pp. 828-835
    • Camelliti, P.1    Green, C.R.2    LeGrice, I.3    Kohl, P.4
  • 10
    • 70349757050 scopus 로고    scopus 로고
    • Biphasic electrical field stimulation aids in tissue engineering of multicell-type cardiac organoids
    • Chiu LL, Iyer RK, King JP, Radisic M. Biphasic electrical field stimulation aids in tissue engineering of multicell-type cardiac organoids. Tissue Eng Part A 14: 1-13, 2008.
    • (2008) Tissue Eng Part A , vol.14 , pp. 1-13
    • Chiu, L.L.1    Iyer, R.K.2    King, J.P.3    Radisic, M.4
  • 11
    • 34547415140 scopus 로고    scopus 로고
    • Spatially discordant voltage alternans cause wavebreaks in ventricular fibrillation
    • Choi BR, Jang W, Salama G. Spatially discordant voltage alternans cause wavebreaks in ventricular fibrillation. Heart Rhythm 4: 1057-1068, 2007.
    • (2007) Heart Rhythm , vol.4 , pp. 1057-1068
    • Choi, B.R.1    Jang, W.2    Salama, G.3
  • 12
    • 0029128101 scopus 로고
    • Implantable biohybrid artificial organs
    • Colton CK. Implantable biohybrid artificial organs. Cell Transplant 4: 415-436, 1995.
    • (1995) Cell Transplant , vol.4 , pp. 415-436
    • Colton, C.K.1
  • 13
    • 36849044035 scopus 로고    scopus 로고
    • Rods, tori, and honeycombs: The directed self-assembly of microtissues with prescribed microscale geometries
    • Dean DM, Napolitano AP, Youssef J, Morgan JR. Rods, tori, and honeycombs: the directed self-assembly of microtissues with prescribed microscale geometries. FASEB J 21: 4005-4012, 2007.
    • (2007) FASEB J , vol.21 , pp. 4005-4012
    • Dean, D.M.1    Napolitano, A.P.2    Youssef, J.3    Morgan, J.R.4
  • 14
    • 79955039546 scopus 로고    scopus 로고
    • Fibroblasts, myofibroblasts, and fibrosis: Fact, fiction, and the future
    • Duffy HS. Fibroblasts, myofibroblasts, and fibrosis: fact, fiction, and the future. J Cardiovas Pharmacol 57: 373-375, 2011.
    • (2011) J Cardiovas Pharmacol , vol.57 , pp. 373-375
    • Duffy, H.S.1
  • 15
    • 0032482142 scopus 로고    scopus 로고
    • Virtual electrode-induced phase singularity: A basic mechanism of defibrillation failure
    • Efimov IR, Cheng Y, Van Wagoner DR, Mazgalev T, Tchou PJ. Virtual electrode-induced phase singularity: a basic mechanism of defibrillation failure. Circ Res 82: 918-925, 1998.
    • (1998) Circ Res , vol.82 , pp. 918-925
    • Efimov, I.R.1    Cheng, Y.2    Van Wagoner, D.R.3    Mazgalev, T.4    Tchou, P.J.5
  • 17
    • 40949165427 scopus 로고    scopus 로고
    • Fibrosis and hypertrophy induced by Trypanosoma cruzi in a three-dimensional cardiomyocyte-culture system
    • Garzoni LR, Adesse D, Soares MJ, Rossi MI, Borojevic R, de Meirelles Mde N. Fibrosis and hypertrophy induced by Trypanosoma cruzi in a three-dimensional cardiomyocyte-culture system. J Infect Dis 197: 906-915, 2008.
    • (2008) J Infect Dis , vol.197 , pp. 906-915
    • Garzoni, L.R.1    Adesse, D.2    Soares, M.J.3    Rossi, M.I.4    Borojevic, R.5    de Meirelles Mde, N.6
  • 18
    • 0042232510 scopus 로고    scopus 로고
    • Coupling of cardiac electrical activity over extended distances by fibroblasts of cardiac origin
    • Gaudesius G, Miragoli M, Thomas SP, Rohr S. Coupling of cardiac electrical activity over extended distances by fibroblasts of cardiac origin. Circ Res 93: 421-428, 2003.
    • (2003) Circ Res , vol.93 , pp. 421-428
    • Gaudesius, G.1    Miragoli, M.2    Thomas, S.P.3    Rohr, S.4
  • 19
  • 20
    • 0029766520 scopus 로고    scopus 로고
    • Changes in action potentials and ion currents in long-term cultured neonatal rat ventricular cells
    • Guo W, Kamiya K, Cheng J, Toyama J. Changes in action potentials and ion currents in long-term cultured neonatal rat ventricular cells. Am J Physiol Cell Physiol 271: C93-C102, 1996.
    • (1996) Am J Physiol Cell Physiol , vol.271
    • Guo, W.1    Kamiya, K.2    Cheng, J.3    Toyama, J.4
  • 21
    • 0015044633 scopus 로고
    • In vitro organization of dissociated rat cardiac cells into beating three-dimensional structures
    • Halbert SP, Bruderer R, Lin TM. In vitro organization of dissociated rat cardiac cells into beating three-dimensional structures. J Exp Med 133: 677-695, 1971.
    • (1971) J Exp Med , vol.133 , pp. 677-695
    • Halbert, S.P.1    Bruderer, R.2    Lin, T.M.3
  • 22
    • 33746843994 scopus 로고    scopus 로고
    • Regulation of cardiomyocyte signaling by RGS proteins: Differential selectivity towards G proteins and susceptibility to regulation
    • Hao J, Michalek C, Zhang W, Zhu M, Xu X, Mende U. Regulation of cardiomyocyte signaling by RGS proteins: differential selectivity towards G proteins and susceptibility to regulation. J Mol Cell Cardiol 41: 51-61, 2006.
    • (2006) J Mol Cell Cardiol , vol.41 , pp. 51-61
    • Hao, J.1    Michalek, C.2    Zhang, W.3    Zhu, M.4    Xu, X.5    Mende, U.6
  • 28
    • 1642385430 scopus 로고    scopus 로고
    • Microscale tissue engineering using gravityenforced cell assembly
    • Kelm JM, Fussenegger M. Microscale tissue engineering using gravityenforced cell assembly. Trends Biotechnol 22: 195-202, 2004.
    • (2004) Trends Biotechnol , vol.22 , pp. 195-202
    • Kelm, J.M.1    Fussenegger, M.2
  • 29
    • 0025186486 scopus 로고
    • A study of the developmental changes in outward currents of rat ventricular myocytes
    • Kilborn MJ, Fedida D. A study of the developmental changes in outward currents of rat ventricular myocytes. J Physiol 430: 37-60, 1990.
    • (1990) J Physiol , vol.430 , pp. 37-60
    • Kilborn, M.J.1    Fedida, D.2
  • 30
    • 26444609054 scopus 로고    scopus 로고
    • Electrical coupling of fibroblasts and myocytes: Relevance for cardiac propagation
    • Kohl P, Camelliti P, Burton FL, Smith GL. Electrical coupling of fibroblasts and myocytes: relevance for cardiac propagation. J Electrocardiol 38: 45-50, 2005.
    • (2005) J Electrocardiol , vol.38 , pp. 45-50
    • Kohl, P.1    Camelliti, P.2    Burton, F.L.3    Smith, G.L.4
  • 31
    • 0025280867 scopus 로고
    • Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study
    • Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 322: 1561-1566, 1990.
    • (1990) N Engl J Med , vol.322 , pp. 1561-1566
    • Levy, D.1    Garrison, R.J.2    Savage, D.D.3    Kannel, W.B.4    Castelli, W.P.5
  • 32
    • 33645743440 scopus 로고    scopus 로고
    • Electrotonic modulation of cardiac impulse conduction by myofibroblasts
    • Miragoli M, Gaudesius G, Rohr S. Electrotonic modulation of cardiac impulse conduction by myofibroblasts. Circ Res 98: 801-810, 2006.
    • (2006) Circ Res , vol.98 , pp. 801-810
    • Miragoli, M.1    Gaudesius, G.2    Rohr, S.3
  • 33
    • 34548056795 scopus 로고    scopus 로고
    • Dynamics of the self-assembly of complex cellular aggregates on micromolded nonadhesive hydrogels
    • Napolitano AP, Chai P, Dean DM, Morgan JR. Dynamics of the self-assembly of complex cellular aggregates on micromolded nonadhesive hydrogels. Tissue Eng 13: 2087-2094, 2007.
    • (2007) Tissue Eng , vol.13 , pp. 2087-2094
    • Napolitano, A.P.1    Chai, P.2    Dean, D.M.3    Morgan, J.R.4
  • 35
    • 34648834682 scopus 로고    scopus 로고
    • The third dimension bridges the gap between cell culture and live tissue
    • Pampaloni F, Reynaud EG, Stelzer EH. The third dimension bridges the gap between cell culture and live tissue. Nat Rev Mol Cell Biol 8: 839-845, 2007.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 839-845
    • Pampaloni, F.1    Reynaud, E.G.2    Stelzer, E.H.3
  • 36
    • 49849099122 scopus 로고    scopus 로고
    • Structural coupling of cardiomyocytes and noncardiomyocytes: Quantitative comparisons using a novel micropatterned cell pair assay
    • Pedrotty DM, Klinger RY, Badie N, Hinds S, Kardashian A, Bursac N. Structural coupling of cardiomyocytes and noncardiomyocytes: quantitative comparisons using a novel micropatterned cell pair assay. Am J Physiol Heart Circ Physiol 295: H390-H400, 2008.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Pedrotty, D.M.1    Klinger, R.Y.2    Badie, N.3    Hinds, S.4    Kardashian, A.5    Bursac, N.6
  • 37
    • 68949155547 scopus 로고    scopus 로고
    • Cardiac fibroblast paracrine factors alter impulse conduction and ion channel expression of neonatal rat cardiomyocytes
    • Pedrotty DM, Klinger RY, Kirkton RD, Bursac N. Cardiac fibroblast paracrine factors alter impulse conduction and ion channel expression of neonatal rat cardiomyocytes. Cardiovasc Res 83: 688-697, 2009.
    • (2009) Cardiovasc Res , vol.83 , pp. 688-697
    • Pedrotty, D.M.1    Klinger, R.Y.2    Kirkton, R.D.3    Bursac, N.4
  • 41
    • 60549099921 scopus 로고    scopus 로고
    • Controlling cell position in complex heterotypic 3D microtissues by tissue fusion
    • Rago AP, Dean DM, Morgan JR. Controlling cell position in complex heterotypic 3D microtissues by tissue fusion. Biotechnol Bioeng 102: 1231-1241, 2009.
    • (2009) Biotechnol Bioeng , vol.102 , pp. 1231-1241
    • Rago, A.P.1    Dean, D.M.2    Morgan, J.R.3
  • 42
    • 0026098333 scopus 로고
    • Patterned growth of neonatal rat heart cells in culture. Morphological and electrophysiological characterization
    • Rohr S, Scholly DM, Kleber AG. Patterned growth of neonatal rat heart cells in culture. Morphological and electrophysiological characterization. Circ Res 68: 114-130, 1991.
    • (1991) Circ Res , vol.68 , pp. 114-130
    • Rohr, S.1    Scholly, D.M.2    Kleber, A.G.3
  • 44
    • 0028274652 scopus 로고
    • Subthreshold stimulation of Purkinje fibers interrupts ventricular tachycardia in intact hearts. Experimental study with voltage-sensitive dyes and imaging techniques
    • Salama G, Kanai A, Efimov IR. Subthreshold stimulation of Purkinje fibers interrupts ventricular tachycardia in intact hearts. Experimental study with voltage-sensitive dyes and imaging techniques. Circ Res 74: 604-619, 1994.
    • (1994) Circ Res , vol.74 , pp. 604-619
    • Salama, G.1    Kanai, A.2    Efimov, I.R.3
  • 45
    • 3042526284 scopus 로고    scopus 로고
    • Influence of cytokines and growth factors in ANG II-mediated collagen upregulation by fibroblasts in rats: Role of myocytes
    • Sarkar S, Vellaichamy E, Young D, Sen S. Influence of cytokines and growth factors in ANG II-mediated collagen upregulation by fibroblasts in rats: role of myocytes. Am J Physiol Heart Circ Physiol 287: H107-H117, 2004.
    • (2004) Am J Physiol Heart Circ Physiol , vol.287
    • Sarkar, S.1    Vellaichamy, E.2    Young, D.3    Sen, S.4
  • 46
    • 33748542565 scopus 로고    scopus 로고
    • Electrical pacing counteracts intrinsic shortening of action potential duration of neonatal rat ventricular cells in culture
    • Sathaye A, Bursac N, Sheehy S, Tung L. Electrical pacing counteracts intrinsic shortening of action potential duration of neonatal rat ventricular cells in culture. J Mol Cell Cardiol 41: 633-641, 2006.
    • (2006) J Mol Cell Cardiol , vol.41 , pp. 633-641
    • Sathaye, A.1    Bursac, N.2    Sheehy, S.3    Tung, L.4
  • 47
    • 0037155176 scopus 로고    scopus 로고
    • Fabrication of pulsatile cardiac tissue grafts using a novel 3-dimensional cell sheet manipulation technique and temperature-responsive cell culture surfaces
    • Shimizu T, Yamato M, Isoi Y, Akutsu T, Setomaru T, Abe K, Kikuchi A, Umezu M, Okano T. Fabrication of pulsatile cardiac tissue grafts using a novel 3-dimensional cell sheet manipulation technique and temperature-responsive cell culture surfaces. Circ Res 90: e40-e48, 2002.
    • (2002) Circ Res , vol.90
    • Shimizu, T.1    Yamato, M.2    Isoi, Y.3    Akutsu, T.4    Setomaru, T.5    Abe, K.6    Kikuchi, A.7    Umezu, M.8    Okano, T.9
  • 50
    • 85047676974 scopus 로고
    • Sympathetic innervation modulates ventricular impulse propagation and repolarisation in the immature rat heart
    • Sun LS, Legato MJ, Rosen TS, Steinberg SF, Rosen MR. Sympathetic innervation modulates ventricular impulse propagation and repolarisation in the immature rat heart. Cardiovasc Res 27: 459-463, 1993.
    • (1993) Cardiovasc Res , vol.27 , pp. 459-463
    • Sun, L.S.1    Legato, M.J.2    Rosen, T.S.3    Steinberg, S.F.4    Rosen, M.R.5
  • 51
    • 0032949682 scopus 로고    scopus 로고
    • Molecular mechanisms of myocardial remodeling
    • Swynghedauw B. Molecular mechanisms of myocardial remodeling. Physiol Rev 79: 215-262, 1999.
    • (1999) Physiol Rev , vol.79 , pp. 215-262
    • Swynghedauw, B.1
  • 52
    • 79957514836 scopus 로고    scopus 로고
    • Mechanical coupling between myofibroblasts and cardiomyocytes slows electric conduction in fibrotic cell monolayers
    • Thompson SA, Copeland CR, Reich DH, Tung L. Mechanical coupling between myofibroblasts and cardiomyocytes slows electric conduction in fibrotic cell monolayers. Circulation 123: 2083-2093, 2011.
    • (2011) Circulation , vol.123 , pp. 2083-2093
    • Thompson, S.A.1    Copeland, C.R.2    Reich, D.H.3    Tung, L.4
  • 53
    • 79955014340 scopus 로고    scopus 로고
    • The cardiac fibroblast: Functional and electrophysiological considerations in healthy and diseased hearts
    • Vasquez C, Benamer N, Morley GE. The cardiac fibroblast: functional and electrophysiological considerations in healthy and diseased hearts. J Cardiovasc Pharmacol 57: 380-388, 2011.
    • (2011) J Cardiovasc Pharmacol , vol.57 , pp. 380-388
    • Vasquez, C.1    Benamer, N.2    Morley, G.E.3
  • 54
    • 0026695388 scopus 로고
    • Developmental increases in the inwardly rectifying potassium current of rat ventricular myocytes
    • Wahler GM. Developmental increases in the inwardly rectifying potassium current of rat ventricular myocytes. Am J Physiol Cell Physiol 262: C1266-C1272, 1992.
    • (1992) Am J Physiol Cell Physiol , vol.262
    • Wahler, G.M.1
  • 55
    • 68049093192 scopus 로고    scopus 로고
    • Cardiac alternans induced by fibroblast-myocyte coupling: Mechanistic insights from computational models
    • Xie Y, Garfinkel A, Weiss JN, Qu Z. Cardiac alternans induced by fibroblast-myocyte coupling: mechanistic insights from computational models. Am J Physiol Heart Circ Physiol 297: H775-H784, 2009.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297
    • Xie, Y.1    Garfinkel, A.2    Weiss, J.N.3    Qu, Z.4
  • 56
    • 34547931078 scopus 로고    scopus 로고
    • Modeling tissue morphogenesis and cancer in 3D
    • Yamada KM, Cukierman E. Modeling tissue morphogenesis and cancer in 3D. Cell 130: 601-610, 2007.
    • (2007) Cell , vol.130 , pp. 601-610
    • Yamada, K.M.1    Cukierman, E.2
  • 57
    • 79959893606 scopus 로고    scopus 로고
    • Regulator of G protein signaling 2 is a functionally important negative regulator of angiotensin II-induced cardiac fibroblast responses
    • Zhang P, Su J, King ME, Maldonado AE, Park C, Mende U. Regulator of G protein signaling 2 is a functionally important negative regulator of angiotensin II-induced cardiac fibroblast responses. Am J Physiol Heart Circ Physiol 301: H147-H156, 2011.
    • (2011) Am J Physiol Heart Circ Physiol , vol.301
    • Zhang, P.1    Su, J.2    King, M.E.3    Maldonado, A.E.4    Park, C.5    Mende, U.6


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