Neuroimaging studies of interoception and self-awareness

Neuroimaging of Consciousness

Volumn , Issue , 2013, Pages 207-224

  Garfinkel, Sarah N ^a   Nagai, Yoko ^a   Seth, Anil K ^a   Critchley, Hugo D ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84929561587     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-642-37580-4_11     Document Type: Chapter

References (78)

1. Bharat R, Kavia C, Dasgupta R, Fowler CJ (2005) Functional imaging and the central control of the bladder. J Comp Neurol 493:27-32
2. Blanke O (2012) Multisensory brain mechanisms of bodily self-consciousness. Nat Rev Neurosci 13:556-571
3. Burgess PW, Scott SK, Frith CD (2003) The role of the rostral frontal cortex (area 10) in prospective memory: a lateral versus medial dissociation. Neuropsychologia 41:906-918
4. Cannon WB (1927) Bodily changes in pain, hunger, fear and rage: an account of recent researches into the function of emotional excitement. D. Appleton, New York
5. Craig AD (2002) How do you feel? Interoception: the sense of the physiological condition of the body. Nat Rev Neurosci 3:655-666
6. Craig AD (2003) Interoception: the sense of the physiological condition of the body. Curr Opin Neurobiol 13:500-505
7. Craig AD (2009) How do you feel - now? The anterior insula and human awareness. Nat Rev Neurosci 10:59-70
8. Craig AD (2010) The sentient self. Brain Struct Funct 214:563-577
9. Creswell JD, Way BM, Eisenberger NI, Lieberman MD (2007) Neural correlates of dispositional mindfulness during affect labeling. Psychosom Med 69:560-565
10. Critchley HD (2004) The human cortex responds to an interoceptive challenge. Proc Natl Acad Sci U S A 101:6333-6334
11. Critchley HD (2009) Psychophysiology of neural, cognitive and affective integration: fMRI and autonomic indicants. Int J Psychophysiol 73:88-94
12. Critchley HD, Mathias CJ, Josephs O, O'Doherty J, Zanini S, Dewar BK, Cipolotti L, Shallice T, Dolan RJ (2003) Human cingulate cortex and autonomic control: converging neuroimaging and clinical evidence. Brain 126:2139-2152
13. Critchley HD, Wiens S, Rotshtein P, Ohman A, Dolan RJ (2004) Neural systems supporting interoceptive awareness. Nature Neurosci 7(2):189-195
14. Damasio AR, Tranel D, Damasio HC (1991) Somatic markers and the guidance of behavior: theory and preliminary testing. In: Levin HS, Eisenberg HM, Benton AL (eds) Frontal lobe function and dysfunction. Oxford University Press, New York
15. Devue C, Bredart S (2011) The neural correlates of visual self-recognition. Conscious Cogn 20:40-51
16. Drevets WC, Bogers W, Raichle ME (2002) Functional anatomical correlates of antidepressant drug treatment assessed using PET measures of regional glucose metabolism. Eur Neuropsychopharmacol 12:527-544
17. Farb N A S, Segal Z V, Mayberg H, Bean J, McKeon D, Fatima Z, Anderson AK (2007) Attending to the present: mindfulness meditation reveals distinct neural modes of self-reference. Soc Cogn Affect Neurosci 2:313-322
18. Fleming SM, Weil RS, Nagy Z, Dolan RJ, Rees G (2010) Relating introspective accuracy to individual differences in brain structure. Science 329:1541-1543
19. Frith CD (2012) The role of metacognition in human social interactions. Philos Trans R Soc B-Biological Sci 367:2213-2223
20. Gallagher HL, Frith CD (2003) Functional imaging of 'theory of mind'. Trends Cogn Sci 7:77-83
21. Gallup GG (1982) Self-awareness and the emergence of mind in primates. Am J Primatol 2:237-248
22. Gallup GG, Capper SA (1970) Preference for mirror-image stimulation in finches (Passerdomesticus-domesticus) and parakeets (Melopsittacus-undulatus). Anim Behav 18:621-624
23. Gianaros PJ, van der Veen FM, Jennings JR (2004) Regional cerebral blood flow correlates with heart period and high-frequency heart period variability during working-memory tasks: implications for the cortical and subcortical regulation of cardiac autonomic activity. Psychophysiology 41:521-530
24. Goldin PR, Gross JJ (2010) Effects of mindfulness-based stress reduction (MBSR) on emotion regulation in social anxiety disorder. Emotion 10:83-91
25. Gray MA, Rylander K, Harrison NA, Wallin BG, Critchley HD (2009) Following one's heart: cardiac rhythms gate central initiation of sympathetic reflexes. J Neurosci 29:1817-1825
26. Gross JJ (1998) Antecedent- and response-focused emotion regulation: divergent consequences for experience, expression, and physiology. J Pers Soc Psychol 74:224-237
27. Gusnard DA, Raichle ME (2001) Searching for a baseline: functional imaging and the resting human brain. Nat Rev Neurosci 2:685-694
28. Gusnard DA, Akbudak E, Shulman GL, Raichle ME (2001) Medial prefrontal cortex and self-referential mental activity: relation to a default mode of brain function. Proc Natl Acad Sci U S A 98:4259-4264
29. Harrison NA, Singer T, Rotshtein P, Dolan RJ, Critchley HD (2006) Pupillary contagion: central mechanisms engaged in sadness processing. Soc Cogn Affect Neurosci 1:5-17
30. Harrison NA, Brydon L, Walker C, Gray MA, Steptoe A, Dolan RJ, Critchley HD (2009) Neural origins of human sickness in interoceptive responses to in flammation. Biol Psychiatry 66:415-422
31. Harrison NA, Gray MA, Gianaros PJ, Critchley HD (2010) The embodiment of emotional feelings in the brain. J Neurosci 30:12878-12884
32. Herwig U, Kaffenberger T, Schell C, Jäncke L, Brühl AB (2012) Neutral activity associated with self-reflection. BMC Neurosci 13:52
33. Hobday DI, Aziz Q, Thacker N, Hollander I, Jackson A, Thompson DG (2001) A study of the cortical processing of ano-rectal sensation using functional MRI. Brain 124:361-368
34. Holzel BK, Carmody J, Evans KC, Hoge EA, Dusek JA, Morgan L, Pitman RK, Lazar SW (2010) Stress reduction correlates with structural changes in the amygdala. Soc Cogn Affect Neurosci 5:11-17
35. Holzel BK, Lazar SW, Gard T, Schuman-Olivier Z, Vago DR, Ott U (2011) How does mindfulness meditation work? Proposing mechanisms of action from a conceptual and neural perspective. Perspect Psychol Sci 6:537-559
36. Ivanovski B, Malhi GS (2007) The psychological and neurophysiological concomitants of mindfulness forms of meditation. Acta Neuropsychiatrica 19:76-91
37. Johansen-Berg H, Gutman DA, Behrens T E J, Matthews PM, Rushworth M F S, Katz E, Lozano AM, Mayberg HS (2008) Anatomical connectivity of the subgenual cingulate region targeted with deep brain stimulation for treatment-resistant depression. Cereb Cortex 18:1374-1383
38. Kabat-Zinn J (2003) Mindfulness-based interventions in context: past, present, and future. Clin Psychol-Sci Pract 10:144-156
39. Kaplan JT, Aziz-Zadeh L, Uddin LQ, Iacoboni M (2008) The self across the senses: an fMRI study of self-face and self-voice recognition. Soc Cogn Affect Neurosci 3:218-223
40. Karnath HO, Baier B (2010) Right insula for our sense of limb ownership and self-awareness of actions. Brain Struct Funct 214:411-417
41. Katkin ES, Wiens S, Ohman A (2001) Nonconscious fear conditioning, visceral perception, and the development of gut feelings. Psychol Sci 12:366-370
42. Kircher T T J, Senior C, Phillips ML, Rabe-Hesketh S, Benson PJ, Bullmore ET, Brammer M, Simmons A, Bartels M, David AS (2001) Recognizing one's own face. Cognition 78:B1-B15
43. Lange CG, James W (1967) The emotions. By Carl Georg Lange and William James, etc. (Edited by Knight Dunlap.-Reprinted.). Hafner Publishing Co, New York/London
44. Lazar SW, Bush G, Gollub RL, Fricchione GL, Khalsa G, Benson H (2000) Functional brain mapping or the relaxation response and meditation. Neuroreport 11:1581-1585
45. Lazarus RS (1991) Progress on a cognitive motivational relational theory of emotion. Am Psychol 46:819-834
46. Lemogne C, Delaveau P, Freton M, Guionnet S, Fossati P (2012) Medial prefrontal cortex and the self in major depression. J Affect Disord 136:e1-e11
47. Luders E, Toga AW, Lepore N, Gaser C (2009) The underlying anatomical correlates of long-term meditation: larger hippocampal and frontal volumes of gray matter. Neuroimage 45:672-678
48. Luders E, Clark K, Narr KL, Toga AW (2011) Enhanced brain connectivity in long-term meditation practitioners. Neuroimage 57(4):1308-1316
49. Lutz A, Slagter HA, Dunne JD, Davidson RJ (2008) Cognitive-emotional interactions - attention regulation and monitoring in meditation. Trends Cogn Sci 12:163-169
50. Mayberg HS, Liotti M, Brannan SK, McGinnis S, Mahurin RK, Jerabek PA, Silva JA, Tekell JL, Martin CC, Lancaster JL, Fox PT (1999) Reciprocal limbic-cortical function and negative mood: converging PET findings in depression and normal sadness. Am J Psychiatry 156:675-682
51. Medford N, Critchley HD (2010) Conjoint activity of anterior insular and anterior cingulate cortex: awareness and response. Brain Struct Funct 214:535-549
52. Miele DB, Wager TD, Mitchell JP, Metcalfe J (2011) Dissociating neural correlates of action monitoring and metacognition of agency. J Cogn Neurosci 23:3620-3636
53. Nagai Y, Critchley HD, Featherstone E, Trimble MR, Dolan RJ (2004) Activity in ventromedial prefrontal cortex covaries with sympathetic skin conductance level (SCL): a physiological account of a "default mode" of brain function. Neuroimage 22:243-251
54. Northoff G, Heinzel A, Greck M, Bennpohl F, Dobrowolny H, Panksepp J (2006) Self-referential processing in our brain - a meta-analysis of imaging studies on the self. Neuroimage 31:440-457
55. Ochsner KN, Gross JJ (2005) The cognitive control of emotion. Trends Cogn Sci 9:242-249
56. Parvizi J, Damasio A (2001) Consciousness and the brainstem. Cognition 79:135-160
57. Paulus MP, Stein MB (2006) An insular view of anxiety. Biol Psychiatry 60:383-387
58. Paus T, Koski L, Caramanos Z, Westbury C (1998) Regional differences in the effects of task difficulty and motor output on blood flow response in the human anterior cingulate cortex: a review of 107 PET activation studies. Neuroreport 9:R37-R47
59. Platek SM, Keenan JP, Gallup GG, Mohamed FB (2004) Where am I? The neurological correlates of self and other. Cogn Brain Res 19:114-122
60. Pollatos O, Kirsch W, Schandry R (2005) Brain structures involved in interoceptive awareness and cardioafferent signal processing: a dipole source localization study. Hum Brain Mapp 26:54-64
61. Pollatos O, Herbert BM, Kaufmann C, Auer DP, Schandry R (2007) Interoceptive awareness, anxiety and cardiovascular reactivity to isometric exercise. Int J Psychophysiol 65:167-173
62. Ramasubbu R, Masalovich S, Gaxiola I, Peltier S, Holtzheimer PE, Heim C, Goodyear B, Macqueen G, Mayberg HS (2011) Differential neural activity and connectivity for processing one's own face: a preliminary report. Psychiatry Res-Neuroimaging 194:130-140
63. Schachter S, Singer JE (1962) Cognitive, social, and physiological determinants of emotional state. Psychol Rev 69:379-399
64. Schandry R (1981) Heart beat perception and emotional experience. Psychophysiology 18:483-488
65. Schilbach L, Bzdok D, Timmermans B, Fox PT, Laird AR, Vogeley K, Eickhoff SB (2012) Introspective minds: using ALE meta-analyses to study commonalities in the neural correlates of emotional processing, social & unconstrained cognition. Plos One 7:e30920
66. Seth AK, Suzuki K, Critchley HD (2011) An interoceptive predictive coding model of conscious presence. Front Psychol 2:395
67. Sherrington CS (1948) The integrative action of the nervous system. Cambridge University Press, Cambridge
68. Sperduti M, Martinelli P, Piolino P (2012) A neurocognitive model of meditation based on activation likelihood estimation (ALE) meta-analysis. Conscious Cogn 21:269-276
69. Sui J, Han SH (2007) Self-construal priming modulates neural substrates of self-awareness. Psychol Sci 18:861-866
70. Tsakiris M, Tajadura-Jimenez A, Costantini M (2011) Just a heartbeat away from one's body: interoceptive sensitivity predicts malleability of body-representations. Proc Biol Sci 278:2470-2476
71. van der Meer L, Costafreda S, Aleman A, David AS (2010) Self-reflection and the brain: a theoretical review and meta-analysis of neuroimaging studies with implications for schizophrenia. Neurosci Biobehav Rev 34:935-946
72. Wager TD, Waugh CE, Lindquist M, Noll DC, Fredrickson BL, Taylor SF (2009) Brain mediators of cardiovascular responses to social threat: part I: Reciprocal dorsal and ventral sub-regions of the medial prefrontal cortex and heart-rate reactivity. Neuroimage 47(3):821-835
73. Wagner G, Sinsel E, Sobanski T, Kohler S, Marinou V, Mentzel HJ, Sauer H, Schlosser R G M (2006) Cortical inefficiency in patients with unipolar depression: an event-related MRI study with the stroop task. Biol Psychiatry 59:958-965
74. Wagner G, Koch K, Schachtzabel C, Peikert G, Schultz CC, Reichenbach JR, Sauer H, Schlosser RG (2012) Self-referential processing influences functional activation during cognitive control: an fMRI study. Soc Cogn Affect Neurosci. Epub ahead of print. doi: 10.1093/scan/nss074
75. Whitehead WE, Drescher VM (1980) Perception of gastric contractions and self-control of gastric motility. Psychophysiology 17:552-558
76. Whitehead WE, Drescher VM, Heiman P, Blackwell B (1977) Relation of heart-rate control to heartbeat perception. Biofeedback Self Regul 2:371-392
77. Wiens S, Mezzacappa ES, Katkin ES (2000) Heartbeat detection and the experience of emotions. Cogn Emotion 14:417-427
78. Zaki J, Davis JI, Ochsner KN (2012) Overlapping activity in anterior insula during interoception and emotional experience. Neuroimage 62:493-499