Oral delivery of wafers made from HBsAg-expressing maize germ induces long-term immunological systemic and mucosal responses

Vaccine

Volumn 33, Issue 25, 2015, Pages 2881-2886

  Hayden, Celine A ^a   Fischer, Maria E ^a   Andrews, Bryan L ^a   Chilton, Hayley C ^a   Turner, Debra D ^b   Walker, John H ^a   Tizard, Ian R ^b   Howard, John A ^a  

^a CALIFORNIA POLYTECHNIC STATE UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Anamnestic response; Bioencapsulation; Immunogenicity; Long term immune memory; Maize oral vaccine; Mucosal; Plant vaccine; Subunit vaccine; Supercritical fluid extraction

Indexed keywords

HEPATITIS B SURFACE ANTIGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; RECOMBINANT HEPATITIS B VACCINE; HEPATITIS B ANTIBODY; HEPATITIS B VACCINE; RECOMBINANT VACCINE; SECRETORY IMMUNOGLOBULIN; SUBUNIT VACCINE;

ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIGEN DETECTION; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; FECES ANALYSIS; IMMUNE RESPONSE; IMMUNOGENICITY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOLOGICAL MEMORY; LONG TERM MEMORY; MAIZE; MOUSE; MUCOSA; NONHUMAN; PRIORITY JOURNAL; SEXUALLY TRANSMITTED DISEASE; SUPERCRITICAL FLUID EXTRACTION; ANIMAL; BAGG ALBINO MOUSE; BLOOD; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; HEPATITIS B, CHRONIC; IMMUNOLOGY; MUCOSAL IMMUNITY; ORAL DRUG ADMINISTRATION; PROCEDURES; SECONDARY IMMUNIZATION; VACCINATION;

ADMINISTRATION, ORAL; ANIMALS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEPATITIS B ANTIBODIES; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; HEPATITIS B, CHRONIC; IMMUNITY, MUCOSAL; IMMUNIZATION, SECONDARY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN A, SECRETORY; IMMUNOGLOBULIN G; IMMUNOLOGIC MEMORY; MICE, INBRED BALB C; VACCINATION; VACCINES, SUBUNIT; VACCINES, SYNTHETIC; ZEA MAYS;

EID: 84929511152     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2015.04.080     Document Type: Article

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