Vaginal memory T cells induced by intranasal vaccination are critical for protective T cell recruitment and prevention of genital HSV-2 disease

Journal of Virology

Volumn 88, Issue 23, 2014, Pages 13699-13708

  Sato, Ayuko ^a   Suwanto, Aldina ^a   Okabe, Manami ^a   Sato, Shintaro ^a,e   Nochi, Tomonori ^b   Imai, Takahiko ^a,c   Koyanagi, Naoto ^a   Kunisawa, Jun ^a,d   Kawaguchi, Yasushi ^a   Kiyono, Hiroshi ^a,e  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c NIPPON INSTITUTE FOR BIOLOGICAL SCIENCE   (Japan)

^d NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HERPES SIMPLEX VACCINE; HERPES VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CERVICAL LYMPH NODE; CONTROLLED STUDY; EFFECTOR CELL; FEMALE; GENITAL HERPES; HERPES SIMPLEX VIRUS 2 INFECTION; INFECTION PREVENTION; LYMPHOCYTE MIGRATION; LYMPHOCYTE PROLIFERATION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; VAGINA MUCOSA; VIRAL CLEARANCE; VIRUS ENTRY; VIRUS STRAIN; ANIMAL; C57BL MOUSE; HERPES GENITALIS; HERPES SIMPLEX VIRUS 2; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; INTRANASAL DRUG ADMINISTRATION; MUCOSAL IMMUNITY; T LYMPHOCYTE; VAGINA;

HUMAN HERPESVIRUS 2;

ADMINISTRATION, INTRANASAL; ANIMALS; FEMALE; HERPES GENITALIS; HERPESVIRUS 2, HUMAN; HERPESVIRUS VACCINES; IMMUNITY, MUCOSAL; IMMUNOLOGIC MEMORY; MICE, INBRED C57BL; T-LYMPHOCYTES; VAGINA;

EID: 84911426229     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02279-14     Document Type: Article

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