Effects of mood stabilizers on oxidative stress-induced cell death signaling pathways in the brains of rats subjected to the ouabain-induced animal model of mania. Mood stabilizers exert protective effects against ouabain-induced activation of the cell death pathway.

Journal of Psychiatric Research

Volumn 65, Issue , 2015, Pages 63-70

  Valvassori, Samira S ^a   Resende, Wilson R ^a   Lopes Borges, Jéssica ^a   Mariot, Edemilson ^a   Dal Pont, Gustavo C ^a   Vitto, Marcelo F ^b   Luz, Gabrielle ^b   de Souza, Claudio T ^b   Quevedo, João ^a,c  

^a UNIVERSIDADE DO EXTREMO SUL CATARINENSE   (Brazil)

^b UNIVERSITY OF SOUTHERN SANTA CATARINA   (Brazil)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Bax; Bcl 2; Bipolar disorder; Ouabain; Oxidative stress; P53

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); LITHIUM; OUABAIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; SODIUM CHLORIDE; SUPEROXIDE; VALPROIC ACID; ENZYME INHIBITOR; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANQUILIZER;

ADULT; AMYGDALOID NUCLEUS; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMICAL ANALYSIS; BRAIN HOMOGENATE; CELL ACTIVATION; CELL DENSITY; CONTROLLED STUDY; CORPUS STRIATUM; FRONTAL CORTEX; GLIA CELL; HIPPOCAMPUS; IMMUNOBLOTTING; LIPID PEROXIDATION; LOCOMOTION; MALE; MANIA; MITOCHONDRION; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; OPEN FIELD TEST; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REPEATED DRUG DOSE; SIGNAL TRANSDUCTION; SUBMITOCHONDRIAL PARTICLE; TREATMENT DURATION; ANALYSIS OF VARIANCE; ANIMAL; BIPOLAR DISORDER; BRAIN; CELL DEATH; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; DRUG INTERACTION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; METABOLISM; MOTOR ACTIVITY; PATHOLOGY; WISTAR RAT;

ANALYSIS OF VARIANCE; ANIMALS; ANTIMANIC AGENTS; BIPOLAR DISORDER; BRAIN; CELL DEATH; DISEASE MODELS, ANIMAL; DRUG INTERACTIONS; ENZYME INHIBITORS; INJECTIONS, INTRAVENTRICULAR; MALE; MITOCHONDRIA; MOTOR ACTIVITY; OUABAIN; OXIDATIVE STRESS; RATS; RATS, WISTAR; SUPEROXIDES; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 84929510396     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2015.04.009     Document Type: Article

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