Facilitating access to emotions: Neural signature of EMDR stimulation

PLoS ONE

Volumn 9, Issue 8, 2014, Pages

  Herkt, Deborah ^a   Tumani, Visal ^a   Grön, Georg ^a   Kammer, Thomas ^a   Hofmann, Arne ^b   Abler, Birgit ^a  

^a UNIVERSITY OF ULM   (Germany)

^b EMDR Institut Deutschland ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AMYGDALOID NUCLEUS; ARTICLE; AUDITORY STIMULATION; BEHAVIOR THERAPY; BRAIN FUNCTION; COGNITION; CONTROLLED STUDY; EMOTION; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HIPPOCAMPUS; HUMAN; IMAGE ANALYSIS; IMAGE PROCESSING; NEUROIMAGING; NORMAL HUMAN; OCCIPITAL CORTEX; PARAHIPPOCAMPAL GYRUS; POSTTRAUMATIC STRESS DISORDER; PREFRONTAL CORTEX; STIMULUS RESPONSE; TASK PERFORMANCE; THALAMUS; THALAMUS VENTRAL NUCLEUS; UNIVERSITY STUDENT; ADOLESCENT; EYE MOVEMENT; PHYSIOLOGY; PROCEDURES; QUESTIONNAIRE; YOUNG ADULT;

ACOUSTIC STIMULATION; ADOLESCENT; ADULT; EMOTIONS; EYE MOVEMENT DESENSITIZATION REPROCESSING; EYE MOVEMENTS; FEMALE; HUMANS; PREFRONTAL CORTEX; QUESTIONNAIRES; YOUNG ADULT;

EID: 84929473504     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106350     Document Type: Article

References (56)

1. Bisson J, Andrew M (2007) Psychological treatment of post-traumatic stress disorder (PTSD). Cochrane Database Syst Rev: CD003388.
2. Watts BV, Schnurr PP, Mayo L, Young-Xu Y, Weeks WB, et al. (2013) Meta-analysis of the efficacy of treatments for posttraumatic stress disorder. J Clin Psychiatry 74: e541-550.
3. Shapiro F (1995) Eye Movement Desensitization and Reprocessing. Basic principles, protocols, and procedures. New York: Guilford Press.
4. Shapiro F (2002) EMDR 12 years after its introduction: Past and future research. Journal of Clinical Psychology 58: 1-22.
5. Cahill SP, Carrigan MH, Frueh BC (1999) Does EMDR work? And if so, why?: a critical review of controlled outcome and dismantling research. J Anxiety Disord 13: 5-33. (Pubitemid 29191676)
6. Lee CW, Cuijpers P (2013) A meta-analysis of the contribution of eye movments in processing emotional memories. Journal of Behavioral Therapy and Experimental Psychiatry 44: 231-239.
7. Maxfield L (2008) Considering mechanisms of action in EMDR. Journal of EMDR Practice and Research 2: 234-238.
8. van den Hout MA, Engelhard IM, Rijkeboer MM, Koekebakker J, Hornsveld H, et al. (2011) EMDR: eye movements superior to beeps in taxing working memory and reducing vividness of recollections. Behav Res Ther 49: 92-98.
9. Lansing K, Amen DG, Hanks C, Rudy L (2005) High-resolution brain SPECT imaging and eye movement desensitization and reprocessing in police officers with PTSD. Journal of Neuropsychiatry and Clinical Neuroscience 17: 526-532. (Pubitemid 41790054)
10. Pagani M, Högberg G, Salmaso D, Nardo D, Tärnell B, et al. (2007) Effects of EMDR psychotherapy on 99mTc-HMPAO distribution in occupation-related post-traumatic stress disorder. Nuclear Medicine Communications 28: 757-765. (Pubitemid 47345706)
11. Servan-Schreiber D, Schooler J, Dew MA, Carter C, Bartone P (2006) Eye movement desensitization and reprocessing for posttraumatic stress disorder: a pilot blinded, randomized study of stimulation type. Psychother Psychosom 75: 290-297. (Pubitemid 44200476)
12. Pagani M, Di Lorenzo G, Verardo AR, Nicolais G, Monaco L, et al. (2011) Pre-, intra- and post-treatment EEG imaging of EMDR-Methodology and preliminary results from a single case. Journal of EMDR Practice and Research 5: 42-56.
13. Pagani M, Di Lorenzo G, Verardo AR, Nicolais G, Monaco L, et al. (2012) Neurobiology of EMDR-EEG imaging of treatment efficacy. PloS One 7: e45753.
14. Nijenhuis ER, van der Hart O (2011) Dissociation in trauma: a new definition and comparison with previous formulations. J Trauma Dissociation 12: 416-445.
15. van der Hart O, Nijenhuis ER, Steele K (2005) Dissociation: An insufficiently recognized major feature of complex posttraumatic stress disorder. J Trauma Stress 18: 413-423. (Pubitemid 46421957)
16. van der Kolk B (2000) Posttraumatic stress disorder and the nature of trauma. Dialogues Clin Neurosci 2: 7-22.
17. Bradley R, Greene J, Russ E, Dutra L, Westen D (2005) A multidimensional meta-analysis of psychotherapy for PTSD. Am J Psychiatry 162: 214-227. (Pubitemid 40216198)
18. Ho MSK, Lee CW (2012) Cognitive behaviour therapy versus eye movement desensitization and reprocessing for post-traumatic disorder - is it all in the homework then? Revue européenne de psychologie appliquée 62: 253-260.
19. Van Etten ML, Taylor S (1998) Comparative Efficacy of Treatments for Post-traumatic Stress Disorder: A Meta-Analysis. Clinical Psychology and Psychotherapy 5: 126-144. (Pubitemid 128499454)
20. Sprang G (2001) The Use of Eye Movement Desensitization and Reprocessing (EMDR) in the Treatment of Traumatic Stress and Complicated Mourning: Psychological and Behavioral Outcomes. Research on Social Work Practice 11: 300-320.
21. Korn DL, Leeds AM (2002) Preliminary Evidence of Efficacy for EMDR Resource Development and Installation in the Stabilization Phase of Treatment of Complex Posttraumatic Stress Disorder. Journal of Clinical Psychology 58: 1465-1487. (Pubitemid 35416767)
22. Staudinger MR, Erk S, Abler B, Walter H (2009) Cognitive reappraisal modulates expected value and prediction error encoding in the ventral striatum. Neuroimage 47: 713-721.
23. van den Hout MA, Rijkeboer MM, Engelhard IM, Klugkist I, Hornsveld H, et al. (2012) Tones inferior to eye movements in the EMDR treatment of PTSD. Behav Res Ther 50: 275-279.
24. Bender VA, Bender KJ, Brasier DJ, Feldman DE (2006) Two coincidence detectors for spike timing-dependent plasticity in somatosensory cortex. J Neurosci 26: 4166-4177. (Pubitemid 44315376)
25. Holscher C, Anwyl R, Rowan MJ (1997) Stimulation on the positive phase of hippocampal theta rhythm induces long-term potentiation that can Be depotentiated by stimulation on the negative phase in area CA1 in vivo. J Neurosci 17: 6470-6477. (Pubitemid 27329918)
26. Lanius RA, Vermetten E, Loewenstein RJ, Brand B, Schmahl C, et al. (2010) Emotion modulation in PTSD: Clinical and neurobiological evidence for a dissociative subtype. Am J Psychiatry 167: 640-647.
27. Moser DA, Aue T, Wang Z, Rusconi Serpa S, Favez N, et al. (2013) Limbic brain responses in mothers with post-traumatic stress disorder and comorbid dissociation to video clips of their children. Stress 16: 493-502.
28. Radloff LS (1977) The CES-D scale: A self-report depression scale for research in the general population. Appl Psychol Measurement 1: 385-401.
29. Hautzinger M, Bailer M (1993) Allgemeine Depressionsskala (ADS). Weinheim: Beltz.
30. Laux L, Glanzmann P, Schaffner P, Spielberger CD (1981) Das Stait-Trait-Angstinventar. Weinheim, Germany: Beltz.
31. Gross JJ, John OP (2003) Individual differences in two emotion regulation processes: implications for affect, relationships, and well-being. J Pers Soc Psychol 85: 348-362. (Pubitemid 37394968)
32. Abler B, Kessler H (2009) Emotion Regulation Questionnaire - Eine deutsche Fassung des ERQ von Gross & John. Diagnostica 55: 144-152.
33. Erk S, Walter H, Abler B (2008) Age-related physiological responses to emotion anticipation and exposure. Neuroreport 19: 447-452. (Pubitemid 351301603)
34. Abler B, Erk S, Herwig U, Walter H (2007) Anticipation of aversive stimuli activates extended amygdala in unipolar depression. J Psychiatr Res 41: 511-522. (Pubitemid 46242139)
35. Erk S, Abler B, Walter H (2006) Cognitive modulation of emotion anticipation. Eur J Neurosci 24: 1227-1236. (Pubitemid 44268153)
36. Abler B, Hofer C, Walter H, Erk S, Hoffmann H, et al. (2010) Habitual emotion regulation strategies and depressive symptoms in healthy subjects predict fMRI brain activation patterns related to major depression. Psychiatry Res 183: 105-113.
37. Lohr JM, Lilienfeld SO, Tolin DF, Herbert JD (1999) Eye Movement Desensitization and Reprocessing: an analysis of specific versus nonspecific treatment factors. J Anxiety Disord 13: 185-207. (Pubitemid 29191685)
38. Lohr JM, Tolin DF, Lilienfeld SO (1998) Efficacy of eye movement desensitization and reprocessing: implications for behavior therapy. Behav Ther 29: 123-156. (Pubitemid 28141256)
39. Hornsveld HK, Houtveen J, Vroomen M, Aalbers I, Kapteijn I, et al. (2011) Evaluating the effect of eye movements on positive memories such as those used in Resource Development and Installation. Journal of EMDR Practice and Research 5: 146-155.
40. Van den Hout M, Engelhard IM, Smeets MAM, Horsnveld H, Hoogeveen E, et al. (2010) Counting during recall: Taxing of working memory and reduced vividness and emotionality of negative memories. Applied Cognitive Psychology 24: 303-311.
41. Andrade J, Kavanagh D, Baddeley A (1997) Eye-movements and visual imagery: a working memory approach to the treatment of post-traumatic stress disorder. Br J Clin Psychol 36 (Pt 2): 209-223. (Pubitemid 27234601)
42. Barrowcliff AL, Gray NS, Freeman TCA, Mac-Culloch MJ (2004) Eye movements reduce the vividness, emotional valence and electrodermal arousal associated with negative autobiographical memories. J Forensic Psychiatry Psychol 15: 325-345. (Pubitemid 38867884)
43. Van den Hout M, Engelhard IM (2012) How does EMDR work? J Exp Psychopathol 3: 724-738.
44. Clarke R, Johnstone T (2013) Prefrontal inhibition of threat processing reduces working memory interference. Front Hum Neurosci 7: 228.
45. Anderson MC, Ochsner KN, Kuhl B, Cooper J, Robertson E, et al. (2004) Neural systems underlying the suppression of unwanted memories. Science 303: 232-235. (Pubitemid 38057573)
46. Phan KL, Wager T, Taylor SF, Liberzon I (2002) Functional neuroanatomy of emotion: a meta-analysis of emotion activation studies in PET and fMRI. Neuroimage 16: 331-348. (Pubitemid 34852450)
47. Etkin A, Wager TD (2007) Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. Am J Psychiatry 164: 1476-1488. (Pubitemid 350069724)
48. Lanius RA, Bluhm R, Lanius U, Pain C (2006) A review of neuroimaging studies in PTSD: heterogeneity of response to symptom provocation. J Psychiatr Res 40: 709-729. (Pubitemid 44486243)
49. Bingel U, Tracey I (2008) Imaging CNS modulation of pain in humans. Physiology (Bethesda) 23: 371-380.
50. Tracey I (2008) Imaging pain. Br J Anaesth 101: 32-39.
51. Sprenger T, Valet M, Woltmann R, Zimmer C, Freynhagen R, et al. (2006) Imaging pain modulation by subanesthetic S-(+)-ketamine. Anesth Analg 103: 729-737. (Pubitemid 44548951)
52. Wagner KJ, Sprenger T, Kochs EF, Tolle TR, Valet M, et al. (2007) Imaging human cerebral pain modulation by dose-dependent opioid analgesia: a positron emission tomography activation study using remifentanil. Anesthesiology 106: 548-556. (Pubitemid 46662221)
53. van der Kolk BA, Pelcovitz D, Roth S, Mandel FS, McFarlane A, et al. (1996) Dissociation, somatization, and affect dysregulation: the complexity of adaptation of trauma. Am J Psychiatry 153: 83-93. (Pubitemid 26230447)
54. Foa EB, Kozak MJ (1986) Emotional processing of fear: exposure to corrective information. Psychol Bull 99: 20-35.
55. Shin LM, Orr SP, Carson MA, Rauch SL, Macklin ML, et al. (2004) Regional cerebral blood flow in the amygdala and medial prefrontal cortex during traumatic imagery in male and female Vietnam veterans with PTSD. Arch Gen Psychiatry 61: 168-176. (Pubitemid 38146551)
56. Lanius RA, Williamson PC, Boksman K, Densmore M, Gupta M, et al. (2002) Brain activation during script-driven imagery induced dissociative responses in PTSD: a functional magnetic resonance imaging investigation. Biol Psychiatry 52: 305-311. (Pubitemid 35245969)