-
1
-
-
0347320540
-
Actinic keratosis: Epidemiology and progression to squamous cell carcinoma
-
Lebwohl M: Actinic keratosis: epidemiology and progression to squamous cell carcinoma. Br J Dermatol 2003; 149(suppl 66):31-33.
-
(2003)
Br J Dermatol
, vol.149
, pp. 31-33
-
-
Lebwohl, M.1
-
2
-
-
0033928865
-
Epidemiology of actinic keratoses and squamous cell carcinoma
-
Salasche SJ: Epidemiology of actinic keratoses and squamous cell carcinoma. J Am Acad Dermatol 2000; 42:4-7.
-
(2000)
J Am Acad Dermatol
, vol.42
, pp. 4-7
-
-
Salasche, S.J.1
-
3
-
-
0033936811
-
The nature of solar keratosis: A critical review in historical perspective
-
Heaphy MR Jr, Ackerman AB: The nature of solar keratosis: a critical review in historical perspective. J Am Acad Dermatol 2000; 43:138-150.
-
(2000)
J Am Acad Dermatol
, vol.43
, pp. 138-150
-
-
Heaphy, M.R.1
Ackerman, A.B.2
-
4
-
-
34247376606
-
Actinic keratosis is an early in situ squamous cell carcinoma: A proposal for reclassification
-
Röwert-Huber J, Patel MJ, Forschner T, Ulrich C, Eberle J, Kerl H, Sterry W, Stockfleth E: Actinic keratosis is an early in situ squamous cell carcinoma: a proposal for reclassification. Br J Dermatol 2007; 156(suppl 3):8-12.
-
(2007)
Br J Dermatol
, vol.156
, pp. 8-12
-
-
Röwert-Huber, J.1
Patel, M.J.2
Forschner, T.3
Ulrich, C.4
Eberle, J.5
Kerl, H.6
Sterry, W.7
Stockfleth, E.8
-
5
-
-
33745010916
-
Solar (actinic) keratosis is squamous cell carcinoma
-
Ackerman AB, Mones JM: Solar (actinic) keratosis is squamous cell carcinoma. Br J Dermatol 2006; 155:9-22.
-
(2006)
Br J Dermatol
, vol.155
, pp. 9-22
-
-
Ackerman, A.B.1
Mones, J.M.2
-
6
-
-
0033940686
-
Clinical presentation of actinic keratoses and squamous cell carcinoma
-
Moy RL: Clinical presentation of actinic keratoses and squamous cell carcinoma. J Am Acad Dermatol 2000; 42:8-10.
-
(2000)
J Am Acad Dermatol
, vol.42
, pp. 8-10
-
-
Moy, R.L.1
-
8
-
-
84887326929
-
Euphorbia peplus: 18th-century insights on a 21st-century therapy
-
Nambudiri NS, Nambudiri VE: Euphorbia peplus: 18th-century insights on a 21st-century therapy. JAMA Dermatol 2013; 149:1081.
-
(2013)
JAMA Dermatol
, vol.149
, pp. 1081
-
-
Nambudiri, N.S.1
Nambudiri, V.E.2
-
9
-
-
84857448930
-
Dual mechanism of action of ingenol mebu-tate gel for topical treatment of actinic keratoses: Rapid lesion necrosis followed by lesion-specific immune response
-
Rosen RH, Gupta AK, Tyring SK: Dual mechanism of action of ingenol mebu-tate gel for topical treatment of actinic keratoses: rapid lesion necrosis followed by lesion-specific immune response. J Am Acad Dermatol 2012; 66:486-493.
-
(2012)
J Am Acad Dermatol
, vol.66
, pp. 486-493
-
-
Rosen, R.H.1
Gupta, A.K.2
Tyring, S.K.3
-
10
-
-
0017163186
-
Home treatment of basal cell carcinoma
-
Weedon D, Chicj J: Home treatment of basal cell carcinoma. Med J Aust 1976; 1: 928.
-
(1976)
Med J Aust
, vol.1
, pp. 928
-
-
Weedon, D.1
Chicj, J.2
-
11
-
-
12344290175
-
Antitumor activity of 3-ingenyl angelate: Plasma membrane and mitochondrial disruption and ne-crotic cell death
-
Ogbourne SM, Suhrbier A, Jones B, Cozzi SJ, Boyle GM, Morris M, McAlp-ine D, Johns J, Scott TM, Sutherland KP, Gardner JM, Le TT, Lenarczyk A, Ayl-ward JH, Parsons PG: Antitumor activity of 3-ingenyl angelate: plasma membrane and mitochondrial disruption and ne-crotic cell death. Cancer Res 2004; 64: 2833-2839.
-
(2004)
Cancer Res
, vol.64
, pp. 2833-2839
-
-
Ogbourne, S.M.1
Suhrbier, A.2
Jones, B.3
Cozzi, S.J.4
Boyle, G.M.5
Morris, M.6
McAlp-Ine, D.7
Johns, J.8
Scott, T.M.9
Sutherland, K.P.10
Gardner, J.M.11
Le, T.T.12
Lenarczyk, A.13
Ayl-Ward, J.H.14
Parsons, P.G.15
-
12
-
-
33751583347
-
Neutrophils are a key component of the antitumor efficacy of topical chemotherapy with ingenol-3-angelate
-
Challacombe JM, Suhrbier A, Parsons PG, Jones B, Hampson P, Kavanagh D, Rainger GE, Morris M, Lord JM, Le TT, Hoang-Le D, Ogbourne SM: Neutrophils are a key component of the antitumor efficacy of topical chemotherapy with ingenol-3-angelate. J Immunol 2006; 177:8123-8132.
-
(2006)
J Immunol
, vol.177
, pp. 8123-8132
-
-
Challacombe, J.M.1
Suhrbier, A.2
Parsons, P.G.3
Jones, B.4
Hampson, P.5
Kavanagh, D.6
Rainger, G.E.7
Morris, M.8
Lord, J.M.9
Le, T.T.10
Hoang-Le, D.11
Ogbourne, S.M.12
-
13
-
-
84858289796
-
Ingenol mebutate field-directed treatment of UVB-damaged skin reduces lesion formation and removes mutant p53 patches
-
Cozzi SJ, Ogbourne SM, James C, Rebel HG, de Gruijl FR, Ferguson B, Gardner J, Lee TT, Larcher T, Suhrbier A: Ingenol mebutate field-directed treatment of UVB-damaged skin reduces lesion formation and removes mutant p53 patches. J Invest Dermatol 2012; 132:1263-1271.
-
(2012)
J Invest Dermatol
, vol.132
, pp. 1263-1271
-
-
Cozzi, S.J.1
Ogbourne, S.M.2
James, C.3
Rebel, H.G.4
De Gruijl, F.R.5
Ferguson, B.6
Gardner, J.7
Lee, T.T.8
Larcher, T.9
Suhrbier, A.10
-
14
-
-
12344274453
-
In-genol 3-angelate induces dual modes of cell death and differentially regulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in melanoma cells
-
Gillespie SK, Zhang XD, Hersey P: In-genol 3-angelate induces dual modes of cell death and differentially regulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in melanoma cells. Mol Cancer Ther 2004; 3:1651-1658.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 1651-1658
-
-
Gillespie, S.K.1
Zhang, X.D.2
Hersey, P.3
-
15
-
-
33750536856
-
Induction of senescence in diterpene ester-treated melanoma cells via protein kinase C-depen-dent hyperactivation of the mitogen-activated protein kinase pathway
-
Cozzi SJ, Parsons PG, Ogbourne SM, Pedley J, Boyle GM: Induction of senescence in diterpene ester-treated melanoma cells via protein kinase C-depen-dent hyperactivation of the mitogen-activated protein kinase pathway. Cancer Res 2006; 66:10083-10091.
-
(2006)
Cancer Res
, vol.66
, pp. 10083-10091
-
-
Cozzi, S.J.1
Parsons, P.G.2
Ogbourne, S.M.3
Pedley, J.4
Boyle, G.M.5
-
16
-
-
23744432856
-
PEP005, a selective small-molecule activator of protein kinase C, has potent antileukemic activity mediated via the delta isoform of PKC
-
Hampson P, Chahal H, Khanim F, Hayden R, Mulder A, Assi LK, Bunce CM, Lord JM: PEP005, a selective small-molecule activator of protein kinase C, has potent antileukemic activity mediated via the delta isoform of PKC. Blood 2005; 106:1362-1368.
-
(2005)
Blood
, vol.106
, pp. 1362-1368
-
-
Hampson, P.1
Chahal, H.2
Khanim, F.3
Hayden, R.4
Mulder, A.5
Assi, L.K.6
Bunce, C.M.7
Lord, J.M.8
-
17
-
-
56749156358
-
Antiproliferative activity of PEP005, a novel ingenol angelate that modulates PKC functions, alone and in combination with cytotoxic agents in human colon cancer cells
-
Benhadji KA, Serova M, Ghoul A, Cvit-kovic E, Le Tourneau C, Ogbourne SM, Lokiec F, Calvo F, Hammel P, Faivre S, Raymond E: Antiproliferative activity of PEP005, a novel ingenol angelate that modulates PKC functions, alone and in combination with cytotoxic agents in human colon cancer cells. Br J Cancer 2008; 99:1808-1815.
-
(2008)
Br J Cancer
, vol.99
, pp. 1808-1815
-
-
Benhadji, K.A.1
Serova, M.2
Ghoul, A.3
Cvit-Kovic, E.4
Le Tourneau, C.5
Ogbourne, S.M.6
Lokiec, F.7
Calvo, F.8
Hammel, P.9
Faivre, S.10
Raymond, E.11
-
18
-
-
67349105944
-
Im-munostimulatory cancer chemotherapy using local ingenol-3-angelate and synergy with immunotherapies
-
Le TT, Gardner J, Hoang-Le D, Schmidt CW, MacDonald KP, Lambley E, Schroder WA, Ogbourne SM, Suhrbier A: Im-munostimulatory cancer chemotherapy using local ingenol-3-angelate and synergy with immunotherapies. Vaccine 2009; 27:3053-3062.
-
(2009)
Vaccine
, vol.27
, pp. 3053-3062
-
-
Le, T.T.1
Gardner, J.2
Hoang-Le, D.3
Schmidt, C.W.4
MacDonald, K.P.5
Lambley, E.6
Schroder, W.A.7
Ogbourne, S.M.8
Suhrbier, A.9
-
19
-
-
77954949361
-
Novel antileukemic compound ingenol 3-angelate inhibits T cell apoptosis by activating protein kinase Ctheta
-
Lee WY, Hampson P, Coulthard L, Ali F, Salmon M, Lord JM, Scheel-Toellner D: Novel antileukemic compound ingenol 3-angelate inhibits T cell apoptosis by activating protein kinase Ctheta. J Biol Chem 2010; 285:23889-23898.
-
(2010)
J Biol Chem
, vol.285
, pp. 23889-23898
-
-
Lee, W.Y.1
Hampson, P.2
Coulthard, L.3
Ali, F.4
Salmon, M.5
Lord, J.M.6
Scheel-Toellner, D.7
-
20
-
-
34250644927
-
Circulating T cells in patients with untreated acute myelogenous leukemia are heterogeneous and can be activated through the CD3/TCR complex
-
Ersvaer E, Hampson P, Wendelbo Ø, Lord JM, Gjertsen BT, Bruserud Ø: Circulating T cells in patients with untreated acute myelogenous leukemia are heterogeneous and can be activated through the CD3/TCR complex. Hematology 2007; 12:199-207.
-
(2007)
Hematology
, vol.12
, pp. 199-207
-
-
Ersvaer, E.1
Hampson, P.2
Wendelbo Ø3
Lord, J.M.4
Gjertsen, B.T.5
Bruserud Ø6
-
21
-
-
44249099692
-
The anti-tumor agent, ingenol-3-angelate (PEP005), promotes the recruitment of cytotoxic neutrophils by activation of vascular endothelial cells in a PKC-delta dependent manner
-
Hampson P, Kavanagh D, Smith E, Wang K, Lord JM, Ed Rainger G: The anti-tumor agent, ingenol-3-angelate (PEP005), promotes the recruitment of cytotoxic neutrophils by activation of vascular endothelial cells in a PKC-delta dependent manner. Cancer Immunol Immunother 2008; 57:1241-1251.
-
(2008)
Cancer Immunol Immunother
, vol.57
, pp. 1241-1251
-
-
Hampson, P.1
Kavanagh, D.2
Smith, E.3
Wang, K.4
Lord, J.M.5
Ed Rainger, G.6
-
22
-
-
77953155672
-
The skin cancer chemotherapeutic agent ingenol-3-angelate (PEP005) is a substrate for the epidermal multidrug transporter (ABCB1) and targets tumor vasculature
-
Li L, Shukla S, Lee A, Garfield SH, Malo-ney DJ, Ambudkar SV, Yuspa SH: The skin cancer chemotherapeutic agent ingenol-3-angelate (PEP005) is a substrate for the epidermal multidrug transporter (ABCB1) and targets tumor vasculature. Cancer Res 2010; 70:4509-4519.
-
(2010)
Cancer Res
, vol.70
, pp. 4509-4519
-
-
Li, L.1
Shukla, S.2
Lee, A.3
Garfield, S.H.4
Malo-Ney, D.J.5
Ambudkar, S.V.6
Yuspa, S.H.7
-
23
-
-
58249101137
-
PEP005 (ingenol mebutate) gel, a novel agent for the treatment of actinic keratosis: Results of a randomized, double-blind, vehicle-controlled, multicentre, phase IIa study
-
Siller G, Gebauer K, Welburn P, Kat-samas J, Ogbourne SM: PEP005 (ingenol mebutate) gel, a novel agent for the treatment of actinic keratosis: results of a randomized, double-blind, vehicle-controlled, multicentre, phase IIa study. Australas J Dermatol 2009; 50:16-22.
-
(2009)
Australas J Dermatol
, vol.50
, pp. 16-22
-
-
Siller, G.1
Gebauer, K.2
Welburn, P.3
Kat-Samas, J.4
Ogbourne, S.M.5
-
24
-
-
65749118370
-
Randomized, double-blind, double-dummy, vehicle-controlled study of ingenol mebutate gel 0.025 and 0.05% for actinic keratosis
-
Anderson L, Schmieder GJ, Werschler WP, Tschen EH, Ling MR, Stough DB, Katsamas J: Randomized, double-blind, double-dummy, vehicle-controlled study of ingenol mebutate gel 0.025 and 0.05% for actinic keratosis. J Am Acad Dermatol 2009; 60:934-943.
-
(2009)
J Am Acad Dermatol
, vol.60
, pp. 934-943
-
-
Anderson, L.1
Schmieder, G.J.2
Werschler, W.P.3
Tschen, E.H.4
Ling, M.R.5
Stough, D.B.6
Katsamas, J.7
-
25
-
-
84863229834
-
Ingenol mebutate gel for actinic keratosis
-
Lebwohl M, Swanson N, Anderson LL, Melgaard A, Xu Z, Berman B: Ingenol mebutate gel for actinic keratosis. N Engl J Med 2012; 366:1010-1019.
-
(2012)
N Engl J Med
, vol.366
, pp. 1010-1019
-
-
Lebwohl, M.1
Swanson, N.2
Anderson, L.L.3
Melgaard, A.4
Xu, Z.5
Berman, B.6
-
26
-
-
84879374046
-
Long-term follow-up study of ingenol mebutate gel for the treatment of actinic keratoses
-
Lebwohl M, Shumack S, Stein Gold L, Melgaard A, Larsson T, Tyring SK: Long-term follow-up study of ingenol mebutate gel for the treatment of actinic keratoses. JAMA Dermatol 2013; 149: 666-670.
-
(2013)
JAMA Dermatol
, vol.149
, pp. 666-670
-
-
Lebwohl, M.1
Shumack, S.2
Stein Gold, L.3
Melgaard, A.4
Larsson, T.5
Tyring, S.K.6
-
27
-
-
80054019728
-
Factors related to pain during routine photodynamic therapy: A descriptive study of 301 patients
-
Miller IM, Nielsen JS, Lophaven S, Jem-ec GB: Factors related to pain during routine photodynamic therapy: a descriptive study of 301 patients. J Eur Acad Dermatol Venereol 2011; 25:1275-1281.
-
(2011)
J Eur Acad Dermatol Venereol
, vol.25
, pp. 1275-1281
-
-
Miller, I.M.1
Nielsen, J.S.2
Lophaven, S.3
Jem-Ec, G.B.4
-
29
-
-
84881601345
-
Network meta-analysis of the outcome 'participant complete clearance' in nonimmunosup-pressed participants of eight interventions for actinic keratosis: A follow-up on a Cochrane review
-
Gupta AK, Paquet M: Network meta-analysis of the outcome 'participant complete clearance' in nonimmunosup-pressed participants of eight interventions for actinic keratosis: a follow-up on a Cochrane review. Br J Dermatol 2013; 169:250-259.
-
(2013)
Br J Dermatol
, vol.169
, pp. 250-259
-
-
Gupta, A.K.1
Paquet, M.2
|