Utilizing magnetization transfer imaging to investigate tissue remodeling in a murine model of autosomal dominant polycystic kidney disease

Magnetic Resonance in Medicine

Volumn 75, Issue 4, 2016, Pages 1466-1473

  Kline, Timothy L ^a   Irazabal, Maria V ^a   Ebrahimi, Behzad ^a   Hopp, Katharina ^a   Udoji, Kelly N ^a   Warner, Joshua D ^a   Korfiatis, Panagiotis ^a   Mishra, Prasanna K ^b   Macura, Slobodan I ^b   Venkatesh, Sudhakar K ^a   Lerman, Lilach O ^a   Harris, Peter C ^a,b   Torres, Vicente E ^a   King, Bernard F ^a   Erickson, Bradley J ^a  

^a MAYO CLINIC   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

Author keywords

fibrosis; Gaussian mixture model; histology; in vivo imaging; quantitative MRI; skewness

Indexed keywords

DIAGNOSIS; GAUSSIAN DISTRIBUTION; HIGHER ORDER STATISTICS; HISTOLOGY; MAGNETIZATION; MAMMALS; PATHOLOGY; TISSUE;

FIBROSIS; GAUSSIAN MIXTURE MODEL; IN-VIVO IMAGING; QUANTITATIVE MRIS; SKEWNESS;

MAGNETIC RESONANCE IMAGING;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; HISTOLOGY; IMAGE ANALYSIS; IMAGE RECONSTRUCTION; KIDNEY FIBROSIS; KIDNEY MASS; KIDNEY POLYCYSTIC DISEASE; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; TISSUE REGENERATION; ANIMAL; C57BL MOUSE; DIAGNOSTIC IMAGING; IMAGE PROCESSING; KIDNEY; PROCEDURES;

ANIMALS; FEMALE; IMAGE PROCESSING, COMPUTER-ASSISTED; KIDNEY; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, INBRED C57BL; POLYCYSTIC KIDNEY, AUTOSOMAL DOMINANT;

EID: 84929431568     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.25701     Document Type: Article

References (30)

1. Ecder T, Fick-Brosnahan G, Schrier RW,. Polycystic kidney disease. diseases of the kidney and urinary tract. Philadelphia, PA: Lippincott Williams & Wilkins; 2006.
2. Gabow PA,. Autosomal dominant polycystic kidney disease. New Engl J Med 1993; 329: 332-342.
3. Harris PC, Torres VE,. Polycystic kidney disease. Annu Rev Med 2009; 60: 321-337.
4. Okada H, Ban S, Nagao S, Takahashi H, Suzuki H, Neilson EG,. Progressive renal fibrosis in murine polycystic kidney disease: an immunohistochemical observation. Kidney Int 2000; 58: 587-597.
5. Norman J,. Fibrosis and progression of autosomal dominant polycystic kidney disease (ADPKD). Biochim Biophys Acta 2011; 1812: 1327-1336.
6. Helal I, Fick-Brosnahan GM, Reed-Gitomer B, Schrier RW,. Glomerular hyperfiltration: definitions, mechanisms and clinical implications. Nat Rev Nephrol 2012; 8: 293-300.
7. Bae KT, Grantham JJ,. Imaging for the prognosis of autosomal dominant polycystic kidney disease. Nat Rev Nephrol 2010; 6: 96-106.
8. Chapman AB, Wei W,. Imaging approaches to patients with polycystic kidney disease. Semin Nephrol 2011; 31: 237-244.
9. Grantham JJ, Torres VE, Chapman AB, et al., Volume progression in polycystic kidney disease. New Engl J Med 2006; 354: 2122-2130.
10. Wallace DP, Hou YP, Huang ZL, Nivens E, Savinkova L, Yamaguchi T, Bilgen M,. Tracking kidney volume in mice with polycystic kidney disease by magnetic resonance imaging. Kidney Int 2008; 73: 778-781.
11. Dousset V, Grossman RI, Ramer KN, Schnall MD, Young LH, Gonzalez-Scarano F, Lavi E, Cohen JA,. Experimental allergic encephalomyelitis and multiple sclerosis: lesion characterization with magnetization transfer imaging. Radiology 1992; 182: 483-491.
12. Pike GB, De Stefano N, Narayanan S, Worsley KJ, Pelletier D, Francis GS, Antel JP, Arnold DL,. Multiple sclerosis: magnetization transfer MR imaging of white matter before lesion appearance on T2-weighted images. Radiology 2000; 215: 824-830.
13. Outwater E, Schnall MD, Braitman LE, Dinsmore BJ, Kressel HY,. Magnetization transfer of hepatic lesions: evaluation of a novel contrast technique in the abdomen. Radiology 1992; 182: 535-540.
14. Adler J, Swanson SD, Schmiedlin-Ren P, Higgins PD, Golembeski CP, Polydorides AD, McKenna BJ, Hussain HK, Verrot TM, Zimmermann EM,. Magnetization transfer helps detect intestinal fibrosis in an animal model of Crohn disease. Radiology 2011; 259: 127-135.
15. Ge Y, Grossman RI, Udupa JK, Babb JS, Kolson DL, McGowan JC,. Magnetization transfer ratio histogram analysis of gray matter in relapsing-remitting multiple sclerosis. Am J Neuroradiol 2001; 22: 470-475.
16. Phillips MD, Grossman RI, Miki Y, Wei L, Kolson DL, van Buchem MA, Polansky M, McGowan JC, Udupa JK,. Comparison of T2 lesion volume and magnetization transfer ratio histogram analysis and of atrophy and measures of lesion burden in patients with multiple sclerosis. Am J Neuroradiol 1998; 19: 1055-1060.
17. Ebrahimi B, Macura SI, Knudsen BE, Grande JP, Lerman LO,. Fibrosis detection in renal artery stenosis mouse model using magnetization transfer MRI. Proc SPIE 2013; 8672: 867.
18. Kajander S, Kallio T, Alanen A, Komu M, Forsstrom J,. Imaging end-stage kidney disease in adults. Low-field MR imaging with magnetization transfer vs. ultrasonography. Acta Radiol 2000; 41: 357-360.
19. Ito K, Hayashida M, Izumitani S, Fujimine T, Onishi T, Genba K,. Magnetisation transfer MR imaging of the kidney: evaluation at 3.0 T in association with renal function. Eur Radiol 2013; 23: 2315-2319.
20. Hopp K, Ward CJ, Hommerding CJ, Nasr SH, Tuan HF, Gainullin VG, Rossetti S, Torres VE, Harris PC,. Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity. J Clin Invest 2012; 122: 4257-4273.
21. Rossetti S, Kubly VJ, Consugar MB, et al., Incompletely penetrant PKD1 alleles suggest a role for gene dosage in cyst initiation in polycystic kidney disease. Kidney Int 2009; 75: 848-855.
22. Vujic M, Heyer CM, Ars E, et al., Incompletely penetrant PKD1 alleles mimic the renal manifestations of ARPKD. J Am Soc Nephrol 2010; 21: 1097-1102.
23. Hopp K, Hommerding CJ, Wang X, Ye H, Harris PC, Torres VE,. Tolvaptan plus Pasireotide shows enhanced efficacy in a PKD1 model. J Am Soc Nephrol 2015; 26: 39-47.
24. Reynolds D,. Gaussian mixture models. In:, Li S, Jain A, editors. Encyclopedia of biometrics. New York, NY: Springer; 2009. p 659-663.
25. Tao Y, Kim J, Schrier RW, Edelstein CL,. Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease. J Am Soc Nephrol 2005; 16: 46-51.
26. Warner JD, Irazabal MV, Krishnamurthi G, King BF, Torres VE, Erickson BJ,. Supervised segmentation of polycystic kidneys: a new application for stereology data. J Digit Imaging 2014; 27: 514-519.
27. Thoeny HC, De Keyzer F, Oyen RH, Peeters RR,. Diffusion-weighted MR imaging of kidneys in healthy volunteers and patients with parenchymal diseases: initial experience. Radiology 2005; 235: 911-917.
28. Li LP, Halter S, Prasad PV,. Blood oxygen level-dependent MR imaging of the kidneys. Magn Reson Imaging C 2008; 16: 613-625.
29. Maril N, Margalit R, Mispelter J, Degani H,. Functional sodium magnetic resonance imaging of the intact rat kidney. Kid Int 2004; 65: 927-935.
30. Dresner MA, Rose GH, Rossman PJ, Muthupillai R, Manduca A, Ehman RL,. Magnetic resonance elastography of skeletal muscle. J Magn Reson Imaging 2001; 13: 269-276.