Tonic zinc inhibits spontaneous firing in dorsal cochlear nucleus principal neurons by enhancing glycinergic neurotransmission

Neurobiology of Disease

Volumn 81, Issue , 2015, Pages 14-19

  Perez Rosello, Tamara ^a   Anderson, Charles T ^a   Ling, Cindy ^a   Lippard, Stephen J ^b   Tzounopoulos, Thanos ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Auditory brainstem; Dorsal cochlear nucleus; Glycinergic neurotransmission; Spontaneous firing; Vesicular zinc transporter; Zinc

Indexed keywords

CHELATING AGENT; STRYCHNINE; UNCLASSIFIED DRUG; ZINC; ZINC CHELATING AGENT ZX1; ZINC TRANSPORTER; ZINC TRANSPORTER ZNT3; AMINO ACID RECEPTOR AFFECTING AGENT; CARRIER PROTEIN; GLYCINE; MEMBRANE PROTEIN; PYRIDINE DERIVATIVE; SLC30A3 PROTEIN, MOUSE; SULFANILIC ACID DERIVATIVE; ZX1 CHELATING AGENT;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DORSAL COCHLEAR NUCLEUS; INHIBITORY POSTSYNAPTIC POTENTIAL; MOUSE; NERVE CELL MEMBRANE POTENTIAL; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; SPINDLE CELL; SPONTANEOUS FIRING; TINNITUS; VOLTAGE CLAMP TECHNIQUE; ACTION POTENTIAL; ANIMAL; COCHLEAR NUCLEUS; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; DRUG INTERACTION; GENETICS; IN VITRO STUDY; INSTITUTE FOR CANCER RESEARCH MOUSE; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; NEWBORN; PATCH CLAMP TECHNIQUE;

ACTION POTENTIALS; ANIMALS; ANIMALS, NEWBORN; CARRIER PROTEINS; CHELATING AGENTS; COCHLEAR NUCLEUS; DRUG INTERACTIONS; GLYCINE; GLYCINE AGENTS; IN VITRO TECHNIQUES; INHIBITORY POSTSYNAPTIC POTENTIALS; MEMBRANE PROTEINS; MICE; MICE, INBRED ICR; MICE, KNOCKOUT; NEURONS; PATCH-CLAMP TECHNIQUES; PYRIDINES; STRYCHNINE; SULFANILIC ACIDS; ZINC;

EID: 84929423015     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2015.03.012     Document Type: Article

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