Intratumoral injection of IFN-alpha dendritic cells after dacarbazine activates anti-tumor immunity: Results from a phase I trial in advanced melanoma

Journal of Translational Medicine

Volumn 13, Issue 1, 2015, Pages

  Rozera, Carmela ^a   Cappellini, Antonini G ^b   D'Agostino, Giuseppina ^a   Santodonato, Laura ^a   Castiello, Luciano ^a   Urbani, Francesca ^a   Macchia, Iole ^a   Aricò, Eleonora ^a   Casorelli, Ida ^c   Sestili, Paola ^a   Montefiore, Enrica ^a   Monque, Domenica ^a   Carlei, Davide ^a   Napolitano, Mariarosaria ^a   Rizza, Paola ^a   Moschella, Federica ^a   Buccione, Carla ^a   Belli, Roberto ^a   Proietti, Enrico ^a   Pavan, Antonio ^c   Marchetti, Paolo ^b,c   Belardelli, Filippo ^a   Capone, Imerio ^a   more..

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Advanced melanoma; Chemo immunotherapy; Dacarbazine; Dendritic cells

Indexed keywords

ALPHA INTERFERON; DACARBAZINE; DENDRITIC CELL VACCINE; GLYCOPROTEIN GP 100; MONOPHENOL MONOOXYGENASE; NY ESO 1 ANTIGEN; CANCER VACCINE; CTAG1B PROTEIN, HUMAN; MELANOCYTE PROTEIN PMEL 17; MEMBRANE PROTEIN; TUMOR ANTIGEN;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER IMMUNOTHERAPY; CLINICAL ARTICLE; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOCYTIC INFILTRATION; MALE; MELANOMA; MEMORY T LYMPHOCYTE; MIDDLE AGED; OVERALL SURVIVAL; PERIPHERAL BLOOD MONONUCLEAR CELL; PHASE 1 CLINICAL TRIAL; T LYMPHOCYTE; VITILIGO; CHEMICALLY INDUCED; CHEMISTRY; CLINICAL TRIAL; CONFOCAL MICROSCOPY; CYTOLOGY; DENDRITIC CELL; DRUG THERAPY; GENE EXPRESSION PROFILING; IMMUNOLOGY; IMMUNOTHERAPY; INTRALESIONAL DRUG ADMINISTRATION; METABOLISM; MONOCYTE; MONONUCLEAR CELL; MULTIMODALITY CANCER THERAPY; PROCEDURES;

ADULT; AGED; ANTIGENS, NEOPLASM; CANCER VACCINES; COMBINED MODALITY THERAPY; DACARBAZINE; DENDRITIC CELLS; DRUG THERAPY; FEMALE; GENE EXPRESSION PROFILING; GP100 MELANOMA ANTIGEN; HUMANS; IMMUNOTHERAPY; INJECTIONS, INTRALESIONAL; INTERFERON-ALPHA; LEUKOCYTES, MONONUCLEAR; MALE; MELANOMA; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; MIDDLE AGED; MONOCYTES; MONOPHENOL MONOOXYGENASE; VITILIGO;

EID: 84929410647     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/s12967-015-0473-5     Document Type: Article

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