Integrated microfluidic card with taqman probes and high- resolution melt analysis to detect tuberculosis drug resistance mutations across 10 genes

mBio

Volumn 6, Issue 2, 2015, Pages

  Pholwat, Suporn ^a   Liu, Jie ^a   Stroup, Suzanne ^a   Gratz, Jean ^a   Banu, Sayera ^b   Mazidur Rahman, S M ^b   Ferdous, Sara Sabrina ^b   Foongladda, Suporn ^c   Boonlert, Duangjai ^c   Ogarkov, Oleg ^d,e   Zhdanova, Svetlana ^d   Kibiki, Gibson ^f   Heysell, Scott ^a   Houpt, Eric ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b International Centre for Diarrheal Diseases and Research   (Bangladesh)

^c MAHIDOL UNIVERSITY   (Thailand)

^d SCIENTIFIC CENTRE FOR FAMILY HEALTH AND HUMAN REPRODUCTION PROBLEMS   (Russian Federation)

^e Irkutsk TB Prevention Dispensary   (Russian Federation)

^f KILIMANJARO CLINICAL RESEARCH INSTITUTE   (Tanzania)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; CAPREOMYCIN; ETHAMBUTOL; ISONIAZID; KANAMYCIN; MOXIFLOXACIN; OFLOXACIN; PYRAZINAMIDE; RIFAMPICIN; STREPTOMYCIN; BACTERIAL DNA; OLIGONUCLEOTIDE PROBE; PRIMER DNA;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIUM CULTURE; CONTROLLED STUDY; EIS GENE; EMBB GENE; GENE MUTATION; GYRA GENE; GYRB GENE; HIGH RESOLUTION MELTING ANALYSIS; INHA GENE; INTERMETHOD COMPARISON; KATG GENE; MEASUREMENT ACCURACY; MICROFLUIDIC ANALYSIS; MOLECULAR PROBE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PNCA GENE; POLYMERASE CHAIN REACTION SYSTEM; PRIORITY JOURNAL; RPOB GENE; RPSL GENE; RRS GENE; SANGER SEQUENCING; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS; DEVICES; EVALUATION STUDY; GENETICS; GENOTYPING TECHNIQUE; LAB ON A CHIP; MICROBIAL SENSITIVITY TEST; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDE PROBE; POLYMERASE CHAIN REACTION; PROCEDURES; TRANSITION TEMPERATURE;

MYCOBACTERIUM TUBERCULOSIS;

DNA PRIMERS; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; GENOTYPING TECHNIQUES; LAB-ON-A-CHIP DEVICES; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDE PROBES; POLYMERASE CHAIN REACTION; TRANSITION TEMPERATURE;

EID: 84929381733     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.02273-14     Document Type: Article

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