Growth hormone enhances LNCaP prostate cancer cell motility

Endocrine Research

Volumn 40, Issue 2, 2015, Pages 97-105

  Nakonechnaya, Alona O ^a   Shewchuk, Brian M ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

Author keywords

Growth hormone; Metastasis; Motility; Prostate cancer; Signal transduction

Indexed keywords

APHIDICOLIN; CHEMOATTRACTANT; F ACTIN; GROWTH HORMONE; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PHOSPHATIDYLINOSITOL 3 KINASE; STAT5 PROTEIN; ACTIN; HUMAN GROWTH HORMONE;

ACTIN FILAMENT; ARTICLE; CANCER CELL MOTILITY; CELL ADHESION; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CELL SURVIVAL; CHEMOKINESIS; CHEMOTAXIS; CONTROLLED STUDY; CYTOPLASM; EXTRACELLULAR MATRIX; IMMUNOBLOTTING; LNCAP CELL LINE; METASTASIS; METASTASIS POTENTIAL; POLYMERIZATION; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TUMOR INVASION; WESTERN BLOTTING; CELL MOTION; DRUG EFFECTS; HUMAN; MALE; METABOLISM; PATHOLOGY; PROSTATE TUMOR; TUMOR CELL LINE;

ACTINS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; HUMAN GROWTH HORMONE; HUMANS; MALE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PROSTATIC NEOPLASMS; SIGNAL TRANSDUCTION;

EID: 84929379391     PISSN: 07435800     EISSN: 15324206     Source Type: Journal    
DOI: 10.3109/07435800.2014.966383     Document Type: Article

References (51)

1. American Cancer Society. Cancer Facts & Figures 2013. Atlanta: American Cancer Society; 2013
2. Taichman RS, Loberg RD, Mehra R, Pienta KJ. The evolving biology and treatment of prostate cancer. J Clin Invest 2007;117: 2351-61
3. Galbraith SM, Duchesne GM. Androgens and prostate cancer: biology, pathology and hormonal therapy. Eur J Cancer 1997;33: 545-54
4. Wilson SS, Crawford ED. Controversies of androgen ablation therapy for metastatic prostate cancer. Curr Pharm Des 2006;12: 799-805
5. Banyard J, Zetter BR. The role of cell motility in prostate cancer. Cancer Metastasis Rev 1998;17:449-58
6. Evangelou AI, Winter SF, Huss WJ, et al. Steroid hormones, polypeptide growth factors, hormone refractory prostate cancer, and the neuroendocrine phenotype. J Cell Biochem 2004;91:671-83
7. Dirnhofer S, Berger C, Hermann M, et al. Coexpression of gonadotropic hormones and their corresponding FSH- and LH/CGreceptors in the human prostate. Prostate 1998;35:212-20
8. Reiter E, Hennuy B, Bruyninx M, et al. Hennen E, effects of pituitary hormones on the prostate. Prostate 1999;38:159-65
9. Reiter E, Kecha O, Hennuy B, et al. Growth hormone directly affects the function of the different lobes of the rat prostate. Endocrinology 1995;136:3338-45
10. Ruan W, Powell L-Braxton, Kopchick JJ, Kleinberg DL. Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development. Endocrinology 1999;140:1984-9
11. Lobie PE, Breipohl W, Aragon JG, Waters MJ. Cellular localization of the growth hormone receptor/binding protein in the male and female reproductive systems. Endocrinology 1990;126:2214-21
12. Reiter E, Bonnet P, Sente B, et al. Growth hormone and prolactin stimulate androgen receptor, insulin-like growth factor-I (IGF-I) and IGF-I receptor levels in the prostate of immature rats. Mol Cell Endocrinol 1992;88:77-87
13. Clemmons DR. Roles of insulin-like growth factor-I and growth hormone in mediating insulin resistance in acromegaly. Pituitary 2002;5:181-3
14. Jenkins PJ, Besser M. Clinical perspective: acromegaly and cancer: a problem. J Clin Endocrinol Metab 2001;86:2935-41
15. Slater MD, Murphy CR. Co-expression of interleukin-6 and human growth hormone in apparently normal prostate biopsies that ultimately progress to prostate cancer using low pH, high temperature antigen retrieval. J Mol Histol 2006;37:37-41
16. Fuhrman B, Barba M, Schunemann HJ, et al. Basal growth hormone concentrations in blood and the risk for prostate cancer: a case-control study. Prostate 2005;64:109-15
17. Wang Z, Luque RM, Kineman RD, et al. Disruption of growth hormone signaling retards prostate carcinogenesis in the Probasin/TAg rat. Endocrinology 2008;149:1366-76
18. Wang Z, Prins GS, Coschigano KT, et al. Disruption of growth hormone signaling retards early stages of prostate carcinogenesis in the C3(1)/T antigen mouse. Endocrinology 2005;146:5188-96
19. Ballesteros M, Leung KC, Ross RJ, et al. Distribution and abundance of messenger ribonucleic acid for growth hormone receptor isoforms in human tissues. J Clin Endocrinol Metab 2000; 85:2865-71
20. Untergasser G, Rumpold H, Hermann M, et al. Proliferative disorders of the aging human prostate: involvement of protein hormones and their receptors. Exp Gerontol 1999;34:275-87
21. van E Garderen, Schalken JA. Morphogenic and tumorigenic potentials of the mammary growth hormone/growth hormone receptor system. Mol Cell Endocrinol 2002;197:153-65
22. Weiss E-Messer, Merom O, Adi A, et al. Growth hormone (GH) receptors in prostate cancer: gene expression in human tissues and cell lines and characterization, GH signaling and androgen receptor regulation in LNCaP cells. Mol Cell Endocrinol 2004;220:109-23
23. Chopin LK, Veveris TL-Lowe, Philipps AF, Herington AC. Co-expression of GH and GHR isoforms in prostate cancer cell lines. Growth Horm IGF Res 2002;12:126-36
24. Nakonechnaya AO, Jefferson HS, Chen X, Shewchuk BM. Differential effects of exogenous and autocrine growth hormone on LNCaP prostate cancer cell proliferation and survival. J Cell Biochem 2013;114:1322-35
25. Wiedermann CJ, Reinisch N, Braunsteiner H. Stimulation of monocyte chemotaxis by human growth hormone and its deactivation by somatostatin. Blood 1993;82:954-60
26. Kaulsay KK, Mertani HC, Lee KO, Lobie PE. Autocrine human growth hormone enhancement of human mammary carcinoma cell spreading is Jak2 dependent. Endocrinology 2000;141:1571-84
27. Lacroix MC, Guibourdenche J, Fournier T, et al. Stimulation of human trophoblast invasion by placental growth hormone. Endocrinology 2005;146:2434-44
28. Bidosee M, Karry R, Weiss E-Messer, Barkey RJ. Growth hormone affects gene expression and proliferation in human prostate cancer cells. Int J Androl 2011;34:124-37
29. Biname F, Pawlak G, Roux P, Hibner U. What makes cells move: requirements and obstacles for spontaneous cell motility. Mol Biosyst 2010;6:648-61
30. Rodriguez LG, Wu X, Guan JL. Wound-healing assay. Methods Mol Biol 2005;294:23-9
31. Whelan JT, Kellogg A, Shewchuk BM, et al. Notch-1 signaling is lost in prostate adenocarcinoma and promotes PTEN gene expression. J Cell Biochem 2009;107:992-1001
32. Moutoussamy S, Kelly PA, Finidori J. Growth-hormone-receptor and cytokine-receptor-family signaling. Eur J Biochem 1998;255: 1-11
33. Carlier MF, Pantaloni D. Control of actin assembly dynamics in cell motility. J Biol Chem 2007;282:23005-9
34. Chesnokova V, Zhou C, Ben-Shlomo A, et al. Melmed, Growth hormone is a cellular senescence target in pituitary and nonpituitary cells. Proc Nat Acad Sci USA 2013;110:E3331-9
35. Hood JD, Cheresh DA. Role of integrins in cell invasion and migration. Nat Rev Cancer 2002;2:91-100
36. Gao CF, Xie Q, Su YL, et al. Proliferation and invasion: plasticity in tumor cells. Proc Natl Acad Sci USA 2005;102:10528-33
37. Hawkins PT, Eguinoa A, Qiu RG, et al. PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase. Curr Biol 1995;5:393-403
38. Wennstrom S, Hawkins P, Cooke F, et al. Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling. Curr Biol 1994;4:385-93
39. Etienne Manneville S, Hall A. Rho GTPases in cell biology. Nature 2002;420:629-35
40. Heasman SJ, Ridley AJ. Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat Rev Mol Cell Biol 2008;9:690-701
41. Schlaepfer DD, Mitra SK. Multiple connections link FAK to cell motility and invasion. Curr Opin Genet Dev 2004;14:92-101
42. Ilic D, Furuta Y, Kanazawa S, et al. Reduced cell motility and enhanced focal adhesion contact formation in cells from FAKdeficient mice. Nature 1995;377:539-44
43. Zhu T, Goh EL, Lobie PE. Growth hormone stimulates the tyrosine phosphorylation and association of p125 focal adhesion kinase (FAK) with JAK2. Fak is not required for stat-mediated transcription. J Biol Chem 1998;273:10682-9
44. Takahashi MO, Takahashi Y, Iida K, et al. Growth hormone stimulates tyrosine phosphorylation of focal adhesion kinase (p125(FAK)) and actin stress fiber formation in human osteoblast- like cells, Saos2. Biochem Biophys Res Commun 1999;263: 100-6
45. Yuan TC, Veeramani S, Lin MF. Neuroendocrine-like prostate cancer cells: neuroendocrine transdifferentiation of prostate adenocarcinoma cells. Endocr Relat Cancer 2007;14:531-47
46. Debidda M, Wang L, Zang H, et al. A role of STAT3 in Rho GTPase-regulated cell migration and proliferation. J Biol Chem 2005;280:17275-85
47. Gu L, Dagvadorj A, Lutz J, et al. Transcription factor Stat3 stimulates metastatic behavior of human prostate cancer cells in vivo, whereas Stat5b has a preferential role in the promotion of prostate cancer cell viability and tumor growth. Am J Pathol 2010; 176:1959-72
48. Abdulghani J, Gu L, Dagvadorj A, et al. Stat3 promotes metastatic progression of prostate cancer. Am J Pathol 2008;172:1717-28
49. Gu L, Vogiatzi P, Puhr M, et al. Stat5 promotes metastatic behavior of human prostate cancer cells in vitro and in vivo. Endocr Relat Cancer 2010;17:481-93
50. Ahonen TJ, Xie J, LeBaron MJ, Nevalainen I. Nevalainen, inhibition of transcription factor Stat5 induces cell death of human prostate cancer cells. J Biol Chem 2003;278:27287-92
51. Iglesias D-Gato, Chuan YC, Wikstrom P, et al. SOCS2 mediates the cross talk between androgen and growth hormone signaling in prostate cancer. Carcinogenesis 2014;35:24-33