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Volumn 13, Issue 1, 2015, Pages 21-25

Cathinone neurotoxicity (“The “3Ms”)

(1)  Karch, Steven B a  

a NONE   (United States)

Author keywords

Cathinones; MDMA; MDVP; Methedrone; Methelone; Bath salts

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; 4' METHYLMETHCATHINONE; AMPHETAMINE; BENZODIAZEPINE; CANNABIS; CATHINONE; COCAINE; DESIGNER DRUG; DOPAMINE TRANSPORTER; METHAMPHETAMINE; METHYLENEDIOXYPYROVALERONE; METHYLONE; NORADRENALIN TRANSPORTER; OXAZEPAM; PSYCHOTROPIC AGENT; SEROTONIN 2A RECEPTOR; UNCLASSIFIED DRUG; ALKALOID;

EID: 84929335284     PISSN: 1570159X     EISSN: 18756190     Source Type: Journal    
DOI: 10.2174/1570159X13666141210225009     Document Type: Article
Times cited : (46)

References (43)
  • 1
    • 85039889876 scopus 로고    scopus 로고
    • Synthetic Cathinones (Bath Salts): An Emerging Domestic Threat
    • U.S. National Defense Intellegence Center. Synthetic Cathinones (Bath Salts): An Emerging Domestic Threat. Situation Report, 2011.
    • (2011) Situation Report
  • 3
    • 33845438736 scopus 로고    scopus 로고
    • European Union: Luxemberg
    • (EMCDDA), European Center for Drugs and Drug Addiction. The state of the drugs problem in Europe; European Union: Luxemberg, 2010.
    • (2010) The state of the drugs problem in Europe
  • 4
    • 78650726892 scopus 로고    scopus 로고
    • Clinical pattern of toxicity associated with the novel synthetic cathinone mephedrone
    • Wood, D. M.; Greene, S. L.; Dargan, P. I. Clinical pattern of toxicity associated with the novel synthetic cathinone mephedrone. EMJ, 2011, 28 (4), 280-2. doi:10.1136/emj.2010.092288
    • (2011) EMJ , vol.28 , Issue.4 , pp. 280-282
    • Wood, D.M.1    Greene, S.L.2    Dargan, P.I.3
  • 6
    • 77956642096 scopus 로고    scopus 로고
    • Analyses of secondgeneration 'legal highs' in the UK: Initial findings
    • Brandt, S.; Sunnall, H.; Measham, F.; Cole, J. Analyses of secondgeneration 'legal highs' in the UK: initial findings. Drug Test Anal., 2010, 2 (8), 377-382. DOI: 10.1002/dta.155
    • (2010) Drug Test Anal , vol.2 , Issue.8 , pp. 377-382
    • Brandt, S.1    Sunnall, H.2    Measham, F.3    Cole, J.4
  • 8
    • 78650470484 scopus 로고    scopus 로고
    • Case series of individuals with analytically confirmed acute mephedrone toxicity
    • Wood, D. M.; Davies, S.; Greene, S. L.; Button, J.; Holt, D. W.; Ramsey, J.; Dargan, P. Case series of individuals with analytically confirmed acute mephedrone toxicity. Clin. Toxicol. (Phila) 2010, 48 (9), 924-7. doi:10.3109/15563650.2010.531021
    • (2010) Clin. Toxicol. (Phila) , vol.48 , Issue.9 , pp. 924-927
    • Wood, D.M.1    Davies, S.2    Greene, S.L.3    Button, J.4    Holt, D.W.5    Ramsey, J.6    Dargan, P.7
  • 9
    • 81855175383 scopus 로고    scopus 로고
    • Mephedrone toxicity in a Scottish emergency department
    • Regan, L.; Mitchelson, M.; Macdonald, C. Mephedrone toxicity in a Scottish emergency department. EMJ, 2011, 28 (12), 1055-8. doi:10.1136/emj.2010.103093
    • (2011) EMJ , vol.28 , Issue.12 , pp. 1055-1058
    • Regan, L.1    Mitchelson, M.2    Macdonald, C.3
  • 10
    • 79960773236 scopus 로고    scopus 로고
    • National Poisons Information, S. Clinical characteristics of mephedrone toxicity reported to the U.K. National Poisons Information Service
    • James, D.; Adams, R. D.; Spears, R.; Cooper, G.; Lupton, D. J.; Thompson, J. P.; Thomas, S. H. National Poisons Information, S. Clinical characteristics of mephedrone toxicity reported to the U.K. National Poisons Information Service. EMJ, 2011, 28 (8), 686-9. doi:10.1136/emj.2010.096636
    • (2011) EMJ , vol.28 , Issue.8 , pp. 686-689
    • James, D.1    Adams, R.D.2    Spears, R.3    Cooper, G.4    Lupton, D.J.5    Thompson, J.P.6    Thomas, S.H.7
  • 11
    • 84872300823 scopus 로고    scopus 로고
    • Emergency department presentations in determining the effectiveness of drug control in the United Kingdom: Mephedrone (4-methylmethcathinone) control appears to be effective using this model
    • Wood, D. M.; Greene, S. L.; Dargan, P. I. Emergency department presentations in determining the effectiveness of drug control in the United Kingdom: mephedrone (4-methylmethcathinone) control appears to be effective using this model. EMJ, 2013, 30 (1), 70-1. doi:10.1136/emermed-2011-200747
    • (2013) EMJ , vol.30 , Issue.1 , pp. 70-71
    • Wood, D.M.1    Greene, S.L.2    Dargan, P.I.3
  • 12
    • 84870302484 scopus 로고    scopus 로고
    • New "Lethal highs": A case of a deadly cocktail of GHB and Mephedrone
    • Aromatario, M.; Bottoni, E.; Santoni, M.; Ciallella, C. New "Lethal highs": A case of a deadly cocktail of GHB and Mephedrone. Forensic Sci.Intl., 2012, 223 (1-3), e38-41
    • (2012) Forensic Sci.Intl , vol.223 , Issue.1-3 , pp. e38-e41
    • Aromatario, M.1    Bottoni, E.2    Santoni, M.3    Ciallella, C.4
  • 14
    • 79952442512 scopus 로고    scopus 로고
    • A case of extreme agitation and death after the use of mephedrone in The Netherlands
    • Lusthof, K. J.; Oosting, R.; Maes, A.; Verschraagen, M.; Dijkhuizen, A.; Sprong, A. G. A case of extreme agitation and death after the use of mephedrone in The Netherlands. Forensic Sci. Intl., 2011, 206 (1-3), e93-5. doi:10.1016/j.forsciint.2010.12.014
    • (2011) Forensic Sci. Intl , vol.206 , Issue.1-3 , pp. e93-e95
    • Lusthof, K.J.1    Oosting, R.2    Maes, A.3    Verschraagen, M.4    Dijkhuizen, A.5    Sprong, A.G.6
  • 15
    • 84901049623 scopus 로고    scopus 로고
    • Toxicological findings in a fatal multidrug intoxication involving mephedrone
    • Gerace, E.; Petrarulo, M.; Bison, F.; Salomone, A.; Vincenti, M. Toxicological findings in a fatal multidrug intoxication involving mephedrone. Forensic Sci. Int., 2014, 243C, 68-73. doi:10.1016/ j.forsciint.2014.04.038
    • (2014) Forensic Sci. Int , vol.243 C , pp. 68-73
    • Gerace, E.1    Petrarulo, M.2    Bison, F.3    Salomone, A.4    Vincenti, M.5
  • 16
    • 28744442954 scopus 로고    scopus 로고
    • Methylone and mCPP, two new drugs of abuse?
    • Bossong, M. G.; Van Dijk, J. P.; Niesink, R. J. Methylone and mCPP, two new drugs of abuse? Addict. Biol., 2005, 10 (4), 321-3. DOI: 10.1080/13556210500350794
    • (2005) Addict. Biol , vol.10 , Issue.4 , pp. 321-323
    • Bossong, M.G.1    Van Dijk, J.P.2    Niesink, R.J.3
  • 18
    • 77953475735 scopus 로고    scopus 로고
    • Beta-keto amphetamines: Studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography-mass spectrometry
    • Meyer, M. R.; Wilhelm, J.; Peters, F. T.; Maurer, H. H. Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography-mass spectrometry. Anal. Bioanal. Chem., 2010, 397 (3), 1225-33. DOI 10.1007/s00216-010-3636-5
    • (2010) Anal. Bioanal. Chem , vol.397 , Issue.3 , pp. 1225-1233
    • Meyer, M.R.1    Wilhelm, J.2    Peters, F.T.3    Maurer, H.H.4
  • 19
    • 84878256611 scopus 로고    scopus 로고
    • In vitro metabolism and pharmacokinetic studies on methylone
    • Pedersen, A. J.; Petersen, T. H.; Linnet, K. In vitro metabolism and pharmacokinetic studies on methylone. Drug Metab. Dispos., 2013, 41 (6), 1247-55. doi: 10.1124/dmd.112.050880
    • (2013) Drug Metab. Dispos , vol.41 , Issue.6 , pp. 1247-1255
    • Pedersen, A.J.1    Petersen, T.H.2    Linnet, K.3
  • 20
    • 33746882802 scopus 로고    scopus 로고
    • Metabolism of the recently encountered designer drug, methylone, in humans and rats
    • Kamata, H. T.; Shima, N.; Zaitsu, K.; Kamata, T.; Miki, A.; Nishikawa, M.; Katagi, M.; Tsuchihashi, H. Metabolism of the recently encountered designer drug, methylone, in humans and rats. Xenobiotica, 2006, 36 (8), 709-23. doi: 10.1080/ 00498250600780191
    • (2006) Xenobiotica , vol.36 , Issue.8 , pp. 709-723
    • Kamata, H.T.1    Shima, N.2    Zaitsu, K.3    Kamata, T.4    Miki, A.5    Nishikawa, M.6    Katagi, M.7    Tsuchihashi, H.8
  • 21
    • 84857748270 scopus 로고    scopus 로고
    • Death Following Recreational Use of Designer Drug "Bath Salts" Containing 3, 4- Methylenedioxypyrovalerone (MDPV)
    • Murray, B. L.; Murphy, C. M.; Beuhler, M. C. Death Following Recreational Use of Designer Drug "Bath Salts" Containing 3, 4- Methylenedioxypyrovalerone (MDPV). J. Med. Toxicol., 2012, 8 (1), 69-75. DOI10.1007/s13181-011-0196-9
    • (2012) J. Med. Toxicol , vol.8 , Issue.1 , pp. 69-75
    • Murray, B.L.1    Murphy, C.M.2    Beuhler, M.C.3
  • 23
    • 34548140526 scopus 로고    scopus 로고
    • Changing times: DNA resequencing and the "nearly normal heart"
    • Karch, S. Changing times: DNA resequencing and the "nearly normal heart". J. Forensic Leg. Med., 2007, 14(7), 389-97. doi:10.1016/j.jflm.2007.04.008
    • (2007) J. Forensic Leg. Med , vol.14 , Issue.7 , pp. 389-397
    • Karch, S.1
  • 26
    • 84857801325 scopus 로고    scopus 로고
    • Lethal serotonin syndrome after methylone and butylone ingestion
    • Warrick, B. J.; Wilson, J.; Hedge, M.; Freeman, S.; Leonard, K.; Aaron, C. Lethal serotonin syndrome after methylone and butylone ingestion. J. Med. Toxicol., 2012, 8 (1), 65-8. DOI10.1007/s13181- 011-0199-6
    • (2012) J. Med. Toxicol , vol.8 , Issue.1 , pp. 65-68
    • Warrick, B.J.1    Wilson, J.2    Hedge, M.3    Freeman, S.4    Leonard, K.5    Aaron, C.6
  • 27
    • 84878374163 scopus 로고    scopus 로고
    • An integrated pharmacokinetic and pharmacodynamic study of a new drug of abuse, methylone, a synthetic cathinone sold as "bath salts"
    • Lopez-Arnau, R.; Martinez-Clemente, J.; Carbo, M.; Pubill, D.; Escubedo, E.; Camarasa, J. An integrated pharmacokinetic and pharmacodynamic study of a new drug of abuse, methylone, a synthetic cathinone sold as "bath salts". Prog. Neuropsychopharmacol. Biol. Psychiatry, 2013, 45, 64-72. doi:10.1016/j.pnpbp. 2013.04.007
    • (2013) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.45 , pp. 64-72
    • Lopez-Arnau, R.1    Martinez-Clemente, J.2    Carbo, M.3    Pubill, D.4    Escubedo, E.5    Camarasa, J.6
  • 29
    • 84908505909 scopus 로고    scopus 로고
    • Pharmacology of novel synthetic stimulants structurally related to the "bath salts" constituent 3, 4- methylenedioxypyrovalerone (MDPV)
    • Marusich, J. A.; Antonazzo, K. R.; Wiley, J. L.; Blough, B. E.; Partilla, J. S.; Baumann, M. H. Pharmacology of novel synthetic stimulants structurally related to the "bath salts" constituent 3, 4- methylenedioxypyrovalerone (MDPV). Neuropharmacology, 2014. doi:10.1016/j.neuropharm.2014.02.016
    • (2014) Neuropharmacology
    • Marusich, J.A.1    Antonazzo, K.R.2    Wiley, J.L.3    Blough, B.E.4    Partilla, J.S.5    Baumann, M.H.6
  • 30
    • 84894025288 scopus 로고    scopus 로고
    • Sudden death after sustained restraint following self-administration of the designer drug alpha-pyrrolidinovalerophenone
    • Nagai, H.; Saka, K.; Nakajima, M.; Maeda, H.; Kuroda, R.; Igarashi, A.; Tsujimura-Ito, T.; Nara, A.; Komori, M.; Yoshida, K., Sudden death after sustained restraint following self-administration of the designer drug alpha-pyrrolidinovalerophenone. Intl. J. Cardiol., 2014, 172 (1), 263-5. doi:10.1016/j.ijcard.2013.12.262
    • (2014) Intl. J. Cardiol , vol.172 , Issue.1 , pp. 263-265
    • Nagai, H.1    Saka, K.2    Nakajima, M.3    Maeda, H.4    Kuroda, R.5    Igarashi, A.6    Tsujimura-Ito, T.7    Nara, A.8    Komori, M.9    Yoshida, K.10
  • 33
    • 38949206676 scopus 로고    scopus 로고
    • Methamphetamine-associated acute left ventricular dysfunction: A variant of stress-induced cardiomyopathy
    • Srikanth, S.; Barua, R.; Ambrose, J. Methamphetamine-associated acute left ventricular dysfunction: a variant of stress-induced cardiomyopathy. Cardiology, 2008, 109 (3), 188-92. DOI:10.1159/ 000106681
    • (2008) Cardiology , vol.109 , Issue.3 , pp. 188-192
    • Srikanth, S.1    Barua, R.2    Ambrose, J.3
  • 34
    • 84875250918 scopus 로고    scopus 로고
    • Analysis of synthetic cathinones commonly found in bath salts in human performance and postmortem toxicology: Method development, drug distribution and interpretation of results
    • Marinetti, L. J.; Antonides, H. M. Analysis of synthetic cathinones commonly found in bath salts in human performance and postmortem toxicology: method development, drug distribution and interpretation of results. J. Anal. Toxicol., 2013, 37 (3), 135-46. doi: 10.1093/jat/bks136
    • (2013) J. Anal. Toxicol , vol.37 , Issue.3 , pp. 135-146
    • Marinetti, L.J.1    Antonides, H.M.2
  • 35
    • 84886747021 scopus 로고    scopus 로고
    • Deaths involving methylenedioxypyrovalerone (MDPV) in Upper East Tennessee
    • Wright, T. H.; Cline-Parhamovich, K.; Lajoie, D.; Parsons, L.; Dunn, M.; Ferslew, K. E. Deaths involving methylenedioxypyrovalerone (MDPV) in Upper East Tennessee. J. Forensic Sci., 2013, 58 (6), 1558-62. DOI: 10.1111/1556- 4029.12260
    • (2013) J. Forensic Sci , vol.58 , Issue.6 , pp. 1558-1562
    • Wright, T.H.1    Cline-Parhamovich, K.2    Lajoie, D.3    Parsons, L.4    Dunn, M.5    Ferslew, K.E.6
  • 37
    • 84897407845 scopus 로고    scopus 로고
    • Intracellular Signaling and Approaches to the Treatment of Schizophrenia and Associated Cognitive Impairment
    • Snyder, G. L.; Vanover, K. E. Intracellular Signaling and Approaches to the Treatment of Schizophrenia and Associated Cognitive Impairment. Curr. Pharm. Design, 2014, 20(31), 5093- 103. DOI: 10.2174/1381612819666131216115417
    • (2014) Curr. Pharm. Design , vol.20 , Issue.31 , pp. 5093-5103
    • Snyder, G.L.1    Vanover, K.E.2
  • 39
    • 84875244963 scopus 로고    scopus 로고
    • Mephedrone does not damage dopamine nerve endings of the striatum, but enhances the neurotoxicity of methamphetamine, amphetamine, and MDMA
    • Angoa-Perez, M.; Kane, M. J.; Briggs, D. I.; Francescutti, D. M.; Sykes, C. E.; Shah, M. M.; Thomas, D. M.; Kuhn, D. M. Mephedrone does not damage dopamine nerve endings of the striatum, but enhances the neurotoxicity of methamphetamine, amphetamine, and MDMA. J. Neurochem., 2013, 125 (1), 102-10. DOI: 10.1111/jnc.12114
    • (2013) J. Neurochem , vol.125 , Issue.1 , pp. 102-110
    • Angoa-Perez, M.1    Kane, M.J.2    Briggs, D.I.3    Francescutti, D.M.4    Sykes, C.E.5    Shah, M.M.6    Thomas, D.M.7    Kuhn, D.M.8
  • 40
    • 0036312970 scopus 로고    scopus 로고
    • Dopamine transport function is elevated in cocaine users
    • Mash, D. C.; Pablo, J.; Ouyang, Q.; Hearn, W. L.; Izenwasser, S. Dopamine transport function is elevated in cocaine users. J. Neurochem., 2002, 81 (2), 292-300. DOI: 10.1046/j.1471-4159. 2002.00820.x
    • (2002) J. Neurochem , vol.81 , Issue.2 , pp. 292-300
    • Mash, D.C.1    Pablo, J.2    Ouyang, Q.3    Hearn, W.L.4    Izenwasser, S.5
  • 42
    • 34247599293 scopus 로고    scopus 로고
    • A murine model of hyperdopaminergic state displays altered respiratory control
    • Vincent, S. G.; Waddell, A. E.; Caron, M. G.; Walker, J. K.; Fisher, J. T. A murine model of hyperdopaminergic state displays altered respiratory control. FASEB, 2007, 21 (7), 1463-71. doi:10.1096/fj. 06-7248com
    • (2007) FASEB , vol.21 , Issue.7 , pp. 1463-1471
    • Vincent, S.G.1    Waddell, A.E.2    Caron, M.G.3    Walker, J.K.4    Fisher, J.T.5
  • 43
    • 84867841572 scopus 로고    scopus 로고
    • Contrasting effects of dmethamphetamine, 3, 4-methylenedioxymethamphetamine, 3, 4- methylenedioxypyrovalerone, and 4-methylmethcathinone on wheel activity in rats
    • Huang, P. K.; Aarde, S. M.; Angrish, D.; Houseknecht, K. L.; Dickerson, T. J.; Taffe, M. A. Contrasting effects of dmethamphetamine, 3, 4-methylenedioxymethamphetamine, 3, 4- methylenedioxypyrovalerone, and 4-methylmethcathinone on wheel activity in rats. Drug Alcohol Depend., 2012, 126 (1-2), 168- 75. doi:10.1016/j.drugalcdep.2012.05.011
    • (2012) Drug Alcohol Depend , vol.126 , Issue.1-2 , pp. 168-175
    • Huang, P.K.1    Aarde, S.M.2    Angrish, D.3    Houseknecht, K.L.4    Dickerson, T.J.5    Taffe, M.A.6


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