A murine model of hyperdopaminergic state displays altered respiratory control

FASEB Journal

Volumn 21, Issue 7, 2007, Pages 1463-1471

  Vincent, Sandra G ^a   Waddell, Andrea E ^a   Caron, Marc G ^b   Walker, Julia K L ^b   Fisher, John T ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ADHD; Body temperature; Chemoreception; Circadian rhythm; DAT; Hypoxia; Respiration

Indexed keywords

CARBON DIOXIDE; DOPAMINE; DOPAMINE TRANSPORTER;

ANIMAL EXPERIMENT; ARTICLE; ATTENTION DEFICIT DISORDER; BODY TEMPERATURE; CONTROLLED STUDY; DOPAMINERGIC ACTIVITY; HYPERCAPNIA; HYPOXIA; INSPIRATORY CAPACITY; KNOCKOUT MOUSE; MOUSE; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RESPIRATION CONTROL; SIGNAL TRANSDUCTION; THERMOREGULATION;

ANIMALS; ANOXIA; BODY TEMPERATURE REGULATION; CIRCADIAN RHYTHM; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; MICE; MICE, KNOCKOUT; MODELS, ANIMAL; PHENOTYPE; RESPIRATION;

MURINAE; MUS;

EID: 34247599293     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.06-7248com     Document Type: Article

References (36)

1. Gonzalez,C., Almaraz, L., Obeso, A., and Rigual, R. (1994) Carotid-body chemoreceptors-from natural stimuli to sensory discharges. Phys. Rev. 74, 829-898
2. Zapata, P., and Torrealba, F. (1984) Blockade of dopamine-induced chemosensory inhibition by domperidone. Neurosci. Lett. 51, 359-364
3. Bisgard, G. E., Mitchell, R. A., and Herbert, D. A. (1979) Effects of dopamine, norepinephrine and 5-hydroxytryptamine on the carotid body of the dog. Respir. Physiol. 37, 61-80
4. Iturriaga, R., Larrain, C., and Zapata, P. (1994) Effects of Dopaminergic Blockade Upon Carotid Chemosensory Activity and Its Hypoxia-Induced Excitation. Brain Res. 663, 145-154
5. Huey, K. A., Brown, I. P., Jordan, M. C., and Powell, F. L. (2000) Changes in dopamine D(2)-receptor modulation of the hypoxic ventilatory response with chronic hypoxia. Respir. Physiol. 123, 177-187
6. Lawrence, A. J., Krstew, E., and Jarrott, B. (1995) Functional dopamine D2 receptors on rat vagal afferent neurones. Br. J. Pharmacol. 114, 1329-1334
7. Sapru, H. N. (1996) Carotid chemoreflex. Neural pathways and transmitters. Adv. Exp. Med. Biol. 410, 357-364
8. Goiny, M., Lagercrantz, H., Srinivasan, M., Ungerstedt, U., and Yamamoto, Y. 1991. Hypoxia-mediated in vivo release of dopamine in nucleus tractus solitarii of rabbits. J. Appl. Physiol. 70, 2395-2400
9. Huey, K. A., Low, M. J., Kelly, M. A., Juarez, R., Szewczak, J. M., and Powell, F. L. (2000) Ventilatory responses to acute and chronic hypoxia in mice: effects of dopamine D-2 receptors. J. Appl. Physiol. 89, 1142-1150
10. Barros, R.C., and Branco, L.G. (2002) Central dopamine modulates anapyrexia but not hyperventilation induced by hypoxia. J. Appl. Physiol 92, 975-981
11. Mortola, J. P., and Seifert, E. L. (2000) Hypoxic depression of circadian rhythms in adult rats. J. Appl. Physiol. 88, 365-368
12. Cox, B., Kerwin, R., and Lee, T. F. (1978) Dopamine receptors in the central thermoregulatory pathways of the rat. J. Physiol. 282, 471-483
13. Lin, M. T., Chandra, A., Tsay, B. L., and Chern, Y. F. (1982) Hypothalamic and striatal dopamine receptor activation inhibits heat production in the rat. Am. J. Physiol. 242, R471-R481
14. Giros, B., Jaber, M., Jones, S. R., Wightman, R. M., and Caron, M. G. (1996) Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379, 606-612
15. Gainetdinov, R. R., Wetsel, W. C., Jones, S. R., Levin, E. D., Jaber, M., and Caron, M. G. (1999) Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science 283, 397-401
16. Gainetdinov, R. R., and Caron, M. G. (2001) Genetics of childhood disorders: XXIV. ADHD, part 8: hyperdopaminergic mice as an animal model of ADHD. J. Am. Acad. Child Adolesc. Psych. 40, 380-382
17. Gainetdinov, R. R., Jones, S. R., and Caron, M. G. (1999) Functional hyperdopaminergia in dopamine transporter knockout mice. Biol. Psych. 46, 303-311
18. Olson, L. G., Hensley, M. J., and Saunders, N. A. (1982) Ventilatory responsiveness to hypercapnic hypoxia during dopamine infusion in humans. Am. Rev. Respir. Dis. 126, 783-787
19. Nielsen, A. M., and Bisgard, G. E. (1984) Differential effects on phrenic output of two dopamine agonists, apomorphine and bromocriptine. Eur. J. Pharmacol. 106, 69-78
20. Nielsen, A. M., and Bisgard, G. E. (1983) Dopaminergic modulation of respiratory timing mechanisms in carotid body-denervated dogs. Respir. Physiol. 53, 71-86
21. Czyzyk-Krzeska, M. F., Lawson, E. E., and Millhorn, D. E. (1992) Expression of D2 dopamine receptor mRNA in the arterial chemoreceptor afferent pathway. J. Auton. Nerv. Syst. 41, 31-39
22. Bairam, A., Dauphin, C., Rousseau, F., and Khandjian, E. W. (1996) Expression of dopamine D2-receptor mRNA isoforms at the peripheral chemoreflex afferent pathway in developing rabbits. Am. J. Respir. Cell Mol. Biol. 15, 374-381
23. Serebrovskaya, T. V., Karaban, I. N., Kolesnikova, E. E., Mishunina, T. M., Swanson, R. J., Beloshitsky, P. V., Ilyin, V. N., Krasuk, A. N., Safronova, O. S., and Kuzminskaya, L. A. (2000) Geriatric men at altitude: hypoxic ventilatory sensitivity and blood dopamine changes. Respiration 67, 253-260
24. Pedersen, M. E. F., Dorrington, K. L., and Robbins, P.A., (1999) Effects of dopamine and domperidone on ventilatory sensistivity to hypoxia after 8 h of isocapnic hypoxia. J. Appl. Physiol. 86, 222-229
25. Frappell, P., Lanthier, C., Baudinette, R. V., and Mortola, J. P. (1992) Metabolism and ventilation in acute hypoxia: a comparative analysis in small mammalian species. Am. J. Physiol. 262, R1040-R1046
26. Hsiao, C., Lahiri, S., and Mokashi, A. (1989) Peripheral and central dopamine receptors in respiratory control. Respir. Physiol. 76, 327-336
27. Smatresk, N.J., Pokorski, M., and Lahiri, S. (1983) Opposing effects of dopamine receptor blockade on ventilation and carotid chemoreceptor activity. J. Appl. Physiol. 54, 1567-1573
28. Jackson, D. M., and Simpson, W. T. 2000. The effect of dopamine on the rapidly adapting receptors in the dog lung. Pulmon. Pharm. Therap. 13, 39-42
29. Wisor, J. P., Nishino, S., Sora, I., Uhl, G. H., Mignot, E., and Edgar, D. M. (2001) Dopaminergic role in stimulant-induced wakefulness. J. Neurosci. 21, 1787-1794
30. Chervin, R. D., Archbold, K. H., Dillon, J.E., Panahi, P., Pituch, K. J., Dahl, R. E., and Guilleminault, C. (2002) Inattention, hyperactivity, and symptoms of sleep-disordered breathing. Pediatrics 109, 449-456
31. Brown, T. E., and McMullen, W. J., Jr. (2001) Attention deficit disorders and sleep/arousal disturbance. Ann. N. Y. Acad. Sci. 931, 271-286
32. Bradley, J. D., and Golden, C. J. (2001) Biological contributions to the presentation and understanding of attention-deficit/ hyperactivity disorder: a review. Clin. Psychol. Rev. 21, 907-929
33. Madras, B. K., Miller, G. M., and Fischman, A. J. (2005) The dopamine transporter and attention-deficit/hyperactivity disorder. Biol. Psychiatry 57, 1397-1409
34. Nigg, J. T. (2005) Neuropsychologic theory and findings in attention-deficit/hyperactivity disorder: the state of the field and salient challenges for the coming decade. Biol. Psychiatry 57, 1424-1435
35. Pliszka, S. R. (2005) The neuropsychopharmacology of attention-deficit/ hyperactivity disorder. Biol. Psychiatry 57, 1385-1390
36. Davids, E., Zhang, K., Tarazi, F. I., and Baldessarini, R. J. (2003) Animal models of attention-deficit hyperactivity disorder. Brain Res. Brain Res. Rev. 42, 1-21