메뉴 건너뛰기




Volumn 13, Issue 1, 2014, Pages

Inhibiting CB1 receptors improves lipogenesis in an in vitro non-alcoholic fatty liver disease model

Author keywords

Endocannabinoids (ECs); Lipogenesis; Nonalcoholic fatty liver disease (NAFLD); Receptor cannabinoid (CB1,CB2)

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CARBOHYDRATE BINDING PROTEIN; CARBOHYDRATE RESPONSIVE ELEMENTS BINDING PROTEIN; FATTY ACID SYNTHASE; LIVER PYRUVATE KINASE; LIVER X RECEPTOR; MESSENGER RNA; OLEATE SODIUM; PALMITIC ACID; PYRUVATE KINASE; RETINOID X RECEPTOR; RIMONABANT; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; UNCLASSIFIED DRUG; CANNABINOID RECEPTOR ANTAGONIST; PIPERIDINE DERIVATIVE; PYRAZOLE DERIVATIVE;

EID: 84929331266     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-13-173     Document Type: Article
Times cited : (36)

References (25)
  • 1
    • 75949100553 scopus 로고    scopus 로고
    • End-stage nonalcoholic fatty liver disease: Evaluation of pathomorphologic features and relationship to cryptogenic cirrhosis from study of explant livers in a living donor liver transplant program
    • Nayak NC, Vasdev N, Saigal S, Soin AS: End-stage nonalcoholic fatty liver disease: evaluation of pathomorphologic features and relationship to cryptogenic cirrhosis from study of explant livers in a living donor liver transplant program. Hum Pathol. 2010, 41: 425-430. 10.1016/j.humpath.2009.06.021
    • (2010) Hum Pathol , vol.41 , pp. 425-430
    • Nayak, N.C.1    Vasdev, N.2    Saigal, S.3    Soin, A.S.4
  • 2
    • 79960109765 scopus 로고    scopus 로고
    • Pathophysiology of non-alcoholic steatohepatitis and basis for treatment
    • Pinzani M: Pathophysiology of non-alcoholic steatohepatitis and basis for treatment. Dig Dis. 2011, 29: 243-248. 10.1159/000323928
    • (2011) Dig Dis , vol.29 , pp. 243-248
    • Pinzani, M.1
  • 3
    • 78651352067 scopus 로고    scopus 로고
    • Prevalence, gender, ethnic variations, and prognosis of NASH
    • 20844903
    • Hashimoto E, Tokushige K: Prevalence, gender, ethnic variations, and prognosis of NASH. J Gastroenterol. 2011, 46 (Suppl 1): 63-69.
    • (2011) J Gastroenterol , vol.46 , pp. 63-69
    • Hashimoto, E.1    Tokushige, K.2
  • 6
    • 84884413612 scopus 로고    scopus 로고
    • Cannabinoid signaling and liver therapeutics
    • Mallat A, Teixeira-Clerc F, Lotersztajn S: Cannabinoid signaling and liver therapeutics. J Hepatol. 2013, 59: 891-896. 10.1016/j.jhep.2013.03.032
    • (2013) J Hepatol , vol.59 , pp. 891-896
    • Mallat, A.1    Teixeira-Clerc, F.2    Lotersztajn, S.3
  • 7
    • 70349309522 scopus 로고    scopus 로고
    • Endocannabinoid system: An overview of its potential in current medical practice
    • 1:CAS:528:DC%2BD1MXht1WhsbzP 19675519
    • Mouslech Z, Valla V: Endocannabinoid system: an overview of its potential in current medical practice. Neuro Endocrinol Lett. 2009, 30: 153-179.
    • (2009) Neuro Endocrinol Lett , vol.30 , pp. 153-179
    • Mouslech, Z.1    Valla, V.2
  • 8
    • 79551483215 scopus 로고    scopus 로고
    • Recent advances in the understanding of the role of the endocannabinoid system in liver diseases
    • Huang L, Quinn MA, Frampton GA, Golden LE, DeMorrow S: Recent advances in the understanding of the role of the endocannabinoid system in liver diseases. Dig Liver Dis. 2011, 43: 188-193. 10.1016/j.dld.2010.08.010
    • (2011) Dig Liver Dis , vol.43 , pp. 188-193
    • Huang, L.1    Quinn, M.A.2    Frampton, G.A.3    Golden, L.E.4    DeMorrow, S.5
  • 9
    • 45849112141 scopus 로고    scopus 로고
    • Endocannabinoid involvement in obesity and hepatic steatosis
    • Kunos G, Osei-Hyiaman D: Endocannabinoid involvement in obesity and hepatic steatosis. Am J Physiol Gastrointest Liver Physiol. 2008, 294 (5): G1101-G1104. 10.1152/ajpgi.00057.2008
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294 , Issue.5 , pp. G1101-G1104
    • Kunos, G.1    Osei-Hyiaman, D.2
  • 11
    • 79951797449 scopus 로고    scopus 로고
    • Cannabinoid receptor-2 selective antagonist negatively regulates receptor activator of nuclear factor kappa B ligand mediated osteoclastogenesis
    • 1:CAS:528:DC%2BC3MXkt1ajuro%3D
    • Geng DC, Xu YZ, Yang HL, Zhu GM, Wang XB, Zhu XS: Cannabinoid receptor-2 selective antagonist negatively regulates receptor activator of nuclear factor kappa B ligand mediated osteoclastogenesis. Chin Med J (Engl). 2011, 124: 586-590.
    • (2011) Chin Med J (Engl) , vol.124 , pp. 586-590
    • Geng, D.C.1    Xu, Y.Z.2    Yang, H.L.3    Zhu, G.M.4    Wang, X.B.5    Zhu, X.S.6
  • 12
    • 57649214103 scopus 로고    scopus 로고
    • Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)
    • Musso G, Gambino R, Cassader M: Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD). Prog Lipid Res. 2009, 48: 1-26. 10.1016/j.plipres.2008.08.001
    • (2009) Prog Lipid Res , vol.48 , pp. 1-26
    • Musso, G.1    Gambino, R.2    Cassader, M.3
  • 13
    • 79955612810 scopus 로고    scopus 로고
    • Endocannabinoid signaling and energy metabolism: A target for dietary intervention
    • Kim J, Li Y, Watkins BA: Endocannabinoid signaling and energy metabolism: a target for dietary intervention. Nutrition. 2011, 27: 624-632. 10.1016/j.nut.2010.11.003
    • (2011) Nutrition , vol.27 , pp. 624-632
    • Kim, J.1    Li, Y.2    Watkins, B.A.3
  • 14
    • 34548392209 scopus 로고    scopus 로고
    • Modulation of sterol regulatory element binding proteins (SREBPs) as potential treatments for non-alcoholic fatty liver disease (NAFLD)
    • Ahmed MH, Byrne CD: Modulation of sterol regulatory element binding proteins (SREBPs) as potential treatments for non-alcoholic fatty liver disease (NAFLD). Drug Discov Today. 2007, 12: 740-747. 10.1016/j.drudis.2007.07.009
    • (2007) Drug Discov Today , vol.12 , pp. 740-747
    • Ahmed, M.H.1    Byrne, C.D.2
  • 15
    • 37349081571 scopus 로고    scopus 로고
    • Role of ChREBP in hepatic steatosis and insulin resistance
    • Denechaud PD, Dentin R, Girard J, Postic C: Role of ChREBP in hepatic steatosis and insulin resistance. FEBS Lett. 2008, 9:582: 68-73.
    • (2008) FEBS Lett , vol.9582 , pp. 68-73
    • Denechaud, P.D.1    Dentin, R.2    Girard, J.3    Postic, C.4
  • 16
    • 79954596966 scopus 로고    scopus 로고
    • Liver x receptors in atherosclerosis and inflammation
    • Im SS, Osborne TF: Liver x receptors in atherosclerosis and inflammation. Circ Res. 2011, 108: 996-1001. 10.1161/CIRCRESAHA.110.226878
    • (2011) Circ Res , vol.108 , pp. 996-1001
    • Im, S.S.1    Osborne, T.F.2
  • 18
    • 80051504630 scopus 로고    scopus 로고
    • Cannabinoid receptor type 1 (CB1R) signaling regulates hepatic gluconeogenesis via induction of endoplasmic reticulum-bound transcription factor cAMP-responsive element-binding protein H (CREBH) in primary hepatocytes
    • Chanda D, Kim DK, Li T, Kim YH, Koo SH, Lee CH, Chiang JY, Choi HS: Cannabinoid receptor type 1 (CB1R) signaling regulates hepatic gluconeogenesis via induction of endoplasmic reticulum-bound transcription factor cAMP-responsive element-binding protein H (CREBH) in primary hepatocytes. J Biol Chem. 2011, 286 (32): 27971-27979. 10.1074/jbc.M111.224352
    • (2011) J Biol Chem , vol.286 , Issue.32 , pp. 27971-27979
    • Chanda, D.1    Kim, D.K.2    Li, T.3    Kim, Y.H.4    Koo, S.H.5    Lee, C.H.6    Chiang, J.Y.7    Choi, H.S.8
  • 19
    • 40149088797 scopus 로고    scopus 로고
    • The blind men 'see' the elephant-the many faces of fatty liver disease
    • Sanal MG: The blind men 'see' the elephant-the many faces of fatty liver disease. World J Gastroenterol. 2008, 14: 831-844. 10.3748/wjg.14.831
    • (2008) World J Gastroenterol , vol.14 , pp. 831-844
    • Sanal, M.G.1
  • 20
    • 77950681221 scopus 로고    scopus 로고
    • Role of cannabinoids in the development of fatty liver (steatosis)
    • Purohit V, Rapaka R, Shurtleff D: Role of cannabinoids in the development of fatty liver (steatosis). AAPS J. 2010, 12: 233-237. 10.1208/s12248-010-9178-0
    • (2010) AAPS J , vol.12 , pp. 233-237
    • Purohit, V.1    Rapaka, R.2    Shurtleff, D.3
  • 21
    • 66649085214 scopus 로고    scopus 로고
    • Minireview: Endocannabinoids and their receptors as targets for obesity therapy
    • De Kloet AD, Woods SC: Minireview: endocannabinoids and their receptors as targets for obesity therapy. Endocrinology. 2009, 150: 2531-2536. 10.1210/en.2009-0046
    • (2009) Endocrinology , vol.150 , pp. 2531-2536
    • De Kloet, A.D.1    Woods, S.C.2
  • 23
    • 34548642096 scopus 로고    scopus 로고
    • Rimonabant as a novel therapeutic option for nonalcoholic steatohepatitis
    • Banasch M, Goetze O, Schmidt WE, Meier JJ: Rimonabant as a novel therapeutic option for nonalcoholic steatohepatitis. Liver Int. 2007, 27: 1152-1155. 10.1111/j.1478-3231.2007.01555.x
    • (2007) Liver Int , vol.27 , pp. 1152-1155
    • Banasch, M.1    Goetze, O.2    Schmidt, W.E.3    Meier, J.J.4
  • 24
    • 79251488405 scopus 로고    scopus 로고
    • Cannabinoid receptor 1 and 2 agonists increase lipid accumulation in hepatocytes
    • De Gottardi A, Spahr L, Ravier-Dall'Antonia F, Hadengue A: Cannabinoid receptor 1 and 2 agonists increase lipid accumulation in hepatocytes. Liver Int. 2010, 30: 1482-1489. 10.1111/j.1478-3231.2010.02298.x
    • (2010) Liver Int , vol.30 , pp. 1482-1489
    • De Gottardi, A.1    Spahr, L.2    Ravier-Dall'Antonia, F.3    Hadengue, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.