Emergence of clonal hematopoiesis in the majority of patients with acquired aplastic anemia

Cancer Genetics

Volumn 208, Issue 4, 2015, Pages 115-128

  Babushok, Daria V ^a,b   Perdigones, Nieves ^b   Perin, Juan C ^b   Olson, Timothy S ^b   Ye, Wenda ^b   Roth, Jacquelyn J ^a,b   Lind, Curt ^b,c   Cattier, Carine ^b   Li, Yimei ^c   Hartung, Helge ^b   Paessler, Michele E ^b   Frank, Dale M ^a   Xie, Hongbo M ^b   Cross, Shanna ^b   Cockroft, Joshua D ^b   Podsakoff, Gregory M ^b   Monos, Dimitrios ^b,c   Biegel, Jaclyn A ^b,c   Mason, Philip J ^b   Bessler, Monica ^a,b  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Aplastic anemia; Bone marrow failure; Clonal hematopoiesis; MDS; Myelodysplastic syndrome

Indexed keywords

HLA ANTIGEN CLASS 1; STAT5B PROTEIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CAMK2G PROTEIN, HUMAN; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL GLYCAN-CLASS A PROTEIN; STAT5 PROTEIN; STAT5B PROTEIN, HUMAN;

ADULT; APLASTIC ANEMIA; ARTICLE; CALCIUM ION CALMODULIN DEPENDENT PROTEIN KINASE II GAMMA GENE; CHILD; CLINICAL ARTICLE; CLONAL VARIATION; COMPARATIVE WHOLE EXOME SEQUENCING; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE ASSOCIATION; DISEASE DURATION; FEMALE; GENE; GENE FREQUENCY; GENE FUNCTION; GENE IDENTIFICATION; HEMATOPOIESIS; HUMAN; IMMUNE RESPONSE; IMMUNOREGULATION; MALE; MIDDLE AGED; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; MYELODYSPLASTIC SYNDROME; PIGA GENE; PRESCHOOL CHILD; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SOMATIC MUTATION; STAT5B GENE; TRANSCRIPTION REGULATION; ADOLESCENT; BLOOD; DNA SEQUENCE; EXOME; GENETICS; INFANT; MOLECULAR GENETICS; MUTATION; SINGLE NUCLEOTIDE POLYMORPHISM; YOUNG ADULT;

ADOLESCENT; ADULT; ANEMIA, APLASTIC; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CHILD; CHILD, PRESCHOOL; EXOME; FEMALE; HEMATOPOIESIS; HUMANS; INFANT; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; MYELODYSPLASTIC SYNDROMES; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; YOUNG ADULT;

EID: 84929292068     PISSN: 22107762     EISSN: 22107770     Source Type: Journal    
DOI: 10.1016/j.cancergen.2015.01.007     Document Type: Article

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