Age at onset mixture analysis and systematic comparison in schizophrenia spectrum disorders: Is the onset heterogeneity dependent on heterogeneous diagnosis?

Schizophrenia Research

Volumn 164, Issue 1-3, 2015, Pages 83-91

  Nowrouzi, Behdin ^a,b   Kamhi, Roy ^a   Hu, Jayi ^a   Kennedy, James L ^a,c   Matmari, Michelle ^a   De Luca, Vincenzo ^a,c  

^a CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^b LAURENTIAN UNIVERSITY   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Admixture analysis; Age at onset; Ethnicity; Schizophrenia; Winter birth

Indexed keywords

ADMIXTURE ANALYSIS; ADULT; ARTICLE; BIRTH; CANNABIS ADDICTION; CANNABIS USE; CONTROLLED STUDY; DSM-IV; ETHNICITY; FAMILY HISTORY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; ONSET AGE; PREDICTION; PRIORITY JOURNAL; PSYCHOSIS; SCHIZOPHRENIA SPECTRUM DISORDER; STATISTICAL ANALYSIS; STATISTICAL MODEL; VARIANCE; WINTER; ADOLESCENT; AGE DISTRIBUTION; AGED; BAYES THEOREM; MIDDLE AGED; NONPARAMETRIC TEST; RETROSPECTIVE STUDY; SCHIZOPHRENIA; YOUNG ADULT;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGE OF ONSET; AGED; BAYES THEOREM; FEMALE; HUMANS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SCHIZOPHRENIA; STATISTICS, NONPARAMETRIC; YOUNG ADULT;

EID: 84929281674     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2015.03.004     Document Type: Article

References (43)

1. Akanji A., Ohaeri J., Al-Shammri S., Fatania H. Apolipoprotein E polymorphism and clinical disease phenotypes in Arab patients with schizophrenia. Neuropsychobiology 2009, 60(2):67-72.
2. Akanji A.O., Ohaeri J.U., Al-Shammri S., Fatania H.R. Association of blood levels of C-reactive protein with clinical phenotypes in Arab schizophrenic patients. Psychiatry Res. 2009, 169(1):56-61.
3. Aleman A., Kahn R.S., Selten J.-P. Sex differences in the risk of schizophrenia: evidence from meta-analysis. Arch. Gen. Psychiatry 2003, 60(6):565-571.
4. Barnes A. Race, schizophrenia, and admission to state psychiatric hospitals. Adm. Policy Ment. Health Ment. Health Serv. Res. 2004, 31(3):241-252.
5. Byrne M., Agerbo E., Mortensen P.B. Family history of psychiatric disorders and age at first contact in schizophrenia: an epidemiological study. Br. J. Psychiatry 2002, 181(43):s19-s25.
6. Cantor-Graae E., Selten J.-P. Schizophrenia and migration: a meta-analysis and review. Am. J. Psychiatr. 2005, 162(1):12-24.
7. Chambers R.A., Krystal J.H., Self D.W. A neurobiological basis for substance abuse comorbidity in schizophrenia. Biol. Psychiatry 2001, 50(2):71-83.
8. Chen H., Chen J. The likelihood ratio test for homogeneity in finite mixture models. Can. J. Stat. 2001, 29(2):201-215.
9. Davies G., Welham J., Chant D., Torrey E.F., McGrath J. A systematic review and meta-analysis of Northern Hemisphere season of birth studies in schizophrenia. Schizophr. Bull. 2003, 29(3):587-593.
10. De Luca V., Zai C., de Souza R., Polsinelli G., Teo C., WONG A., LE FOIL B., KENNEDY J.L., SHINKAI T. Admixture analysis of age at onset in schizophrenia: genetic association study of 45 candidate loci. Schizophr. Res. 2012, 134(2-3):288-290.
11. Deb P. FMM: Stata Module to Estimate Finite Mixture Models 2007, Boston College Department of Economics: Statistical Software Components S456895, Boston, MA. 11 ed.
12. Deb P., Gallo W.T., Ayyagari P., Fletcher J.M., Sindelar J.L. The effect of job loss on overweight and drinking. J. Health Econ. 2011, 30:317-327.
13. DeLisi L.E. The significance of age of onset for schizophrenia. Schizophr. Bull. 1992, 18(2):209-215.
14. Di C.Z., Liang K.Y. Likelihood ratio testing for admixture models with application to genetic linkage analysis. Biometrics 2011, 67(4):1249-1259.
15. Dixon L. Dual diagnosis of substance abuse in schizophrenia: prevalence and impact on outcomes. Schizophr. Res. 1999, 35:S93-S100.
16. Eranti S., Maccabe J., Bundy H., Murray R. Gender difference in age at onset of schizophrenia: a meta-analysis. Psychol. Med. 2013, 43(01):155-167.
17. Fathalli F., Rouleau G.A., Xiong L., Tabbane K., Benkelfat C., Deguzman R., Zoltan D., Lal S., D'cruz S., Joober R. No association between the DRD3 Ser9Gly polymorphism and schizophrenia. Schizophr. Res. 2008, 98(1):98-104.
18. First M., Spitzer R., Gibbon M., Williams J. Structured Clinical Interview for DSM-IV-TR Axis I Disorders. SCID-I/P, 11/2002 revision 2002, Patient Edition.
19. Fraley C., Raferty A. MCLUST Version 3: an R Package for Normal Mixture Modelling and Model-based Clustering 2006, University of Washington, Seattle, University of Washington, Seattle.
20. Fraley C., Raftery A.E. MCLUST: software for model-based cluster analysis. J. Classif. 1999, 16(2):297-306.
21. Fraley C., Raftery A.E. Enhanced model-based clustering, density estimation, and discriminant analysis software: MCLUST. J. Classif. 2003, 20(2):263-286.
22. Hambrecht M., Häfner H. Substance abuse and the onset of schizophrenia. Biol. Psychiatry 1996, 40(11):1155-1163.
23. Hamshere M.L., Gordon-Smith K., Forty L., Jones L., Caesar S., Fraser C., Hyde S., Tredget J., Kirov G., Jones I. Age-at-onset in bipolar-I disorder: mixture analysis of 1369 cases identifies three distinct clinical sub-groups. J. Affect. Disord. 2009, 116(1):23-29.
24. Hong C.-J., Liu H.-C., Liu T.-Y., Liao D.-L., Tsai S.-J. Association studies of the adenosine A2a receptor (1976T>C) genetic polymorphism in Parkinson's disease and schizophrenia. J. Neural Transm. 2005, 112(11):1503-1510.
25. Joa I., Johannessen J.O., Langeveld J., Friis S., Melle I., Opjordsmoen S., Simonsen E., Vaglum P., McGlashan T., Larsen T.K. Baseline profiles of adolescent vs. adult-onset first-episode psychosis in an early detection program. Acta Psychiatr. Scand. 2009, 119(6):494-500.
26. Köhler S., van der Werf M., Hart B., Morrison G., McCreadie R., Kirkpatrick B., Verkaaik M., Krabbendam L., Verhey F., van Os J. Evidence that better outcome of psychosis in women is reversed with increasing age of onset: a population-based 5-year follow-up study. Schizophr. Res. 2009, 113(2):226-232.
27. Lee K.Y., Ahn Y.M., Joo E.-J., Joo Y.H., Chang J.S., Yoo H.Y., Kim Y.S. Partial evidence of an association between epidermal growth factor A61G polymorphism and age at onset in male schizophrenia. Neurosci. Res. 2006, 56(4):356-362.
28. Leung A., Chue P. Sex differences in schizophrenia, a review of the literature. Acta Psychiatr. Scand. 2000, 101(401):3-38.
29. Leung M., Psych C.M. Sex differences in schizophrenia, a review of the literature. Acta Psychiatr. Scand. 2000, 101(401):3-38.
30. Liu J.J., Norman R.M., Manchanda R., De Luca V. Admixture analysis of age at onset in schizophrenia: evidence of three subgroups in a first-episode sample. Gen. Hosp. Psychiatry 2013, 35:664-667.
31. Mortensen P.B., Pedersen C.B., Westergaard T., Wohlfahrt J., Ewald H., Mors O., et al. Effects of family history and place and season of birth on the risk of schizophrenia. N. Engl. J. Med. 1999, 340:603-608.
32. Niehaus D., Laurent C., Jordaan E., Koen L., Oosthuizen P., Keyter N., Muller J.E., Mbanga N., Deleuze J.F., Mallet J. Suicide attempts in an African schizophrenia population: an assessment of demographic risk factors. Suicide Life Threat. Behav. 2004, 34(3):320-327.
33. Nieratschker V., Frank J., Mühleisen T.W., Strohmaier J., Wendland J.R., Schumacher J., Treutlein J., Breuer R., Jamra R.A., Mattheisen M. The catechol-O-methyl transferase (COMT) gene and its potential association with schizophrenia: findings from a large German case-control and family-based sample. Schizophr. Res. 2010, 122(1):24-30.
34. Öngür D., Lin L., Cohen B.M. Clinical characteristics influencing age at onset in psychotic disorders. Compr. Psychiatry 2009, 50(1):13-19.
35. Otowa T., Tochigi M., Rogers M., Umekage T., Kato N., Sasaki T. Insertional polymorphism of endogenous retrovirus HERV-K115 in schizophrenia. Neurosci. Lett. 2006, 408(3):226-229.
36. Panariello F., O'Driscoll L., de Souza R.P., Tiwari A., Manchia M., Kennedy J., De Luca V. Age at onset in Canadian schizophrenia patients: admixture analysis. Schizophr. Res. 2010, 122(1-3):278.
37. Rabinowitz J., Levine S.Z., Häfner H. A population based elaboration of the role of age of onset on the course of schizophrenia. Schizophr. Res. 2006, 88(1):96-101.
38. Schürhoff F., Golmard J.L., Szöke A., Bellivier F., Berthier A., Méary A., Rouillon F., Leboyer M. Admixture analysis of age at onset in schizophrenia. Schizophr. Res. 2004, 71(1):35-41.
39. StataCorp Stata Statistical Software: Release 11.0 2009, Stata Corporation, College Station, TX.
40. Svensson A.C., Lichtenstein P., Sandin S., Öberg S., Sullivan P.F., Hultman C.M. Familial aggregation of schizophrenia: the moderating effect of age at onset, parental immigration, paternal age and season of birth. Scand. J. Public Health 2012, 40(1):43-50.
41. Torrey E.F., Miller J., Rawlings R., Yolken R.H. Seasonality of births in schizophrenia and bipolar disorder: a review of the literature. Schizophr. Res. 1997, 28:1-38.
42. Tsuang M. Schizophrenia: genes and environment. Biol. Psychiatry 2000, 47(3):210-220.
43. Vinokur D., Levine S., Roe D., Krivoy A., Fischel T. Age of onset group characteristics in forensic patients with schizophrenia. Eur. Psychiatry 2014, 29(3):149-152.