Admixture analysis of age at onset in schizophrenia: Evidence of three subgroups in a first-episode sample

General Hospital Psychiatry

Volumn 35, Issue 6, 2013, Pages 664-667

  Liu, Jerome J ^a   Norman, Ross M G ^b   Manchanda, Raul ^b   De Luca, Vincenzo ^c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Admixture analysis; Age at onset; Recall bias; Schizophrenia

Indexed keywords

ACADEMIC ACHIEVEMENT; ADMIXTURE ANALYSIS; AGE DISTRIBUTION; ANALYTIC METHOD; ARTICLE; CANADA; CLINICAL FEATURE; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DRUG ABUSE; DSM-IV; HERITABILITY; MARRIAGE; MODEL; NEUROBIOLOGY; ONSET AGE; SCHIZOPHRENIA; SEX DIFFERENCE;

ADMIXTURE ANALYSIS; AGE AT ONSET; RECALL BIAS; SCHIZOPHRENIA;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGE OF ONSET; CANADA; COHORT STUDIES; EDUCATIONAL STATUS; FEMALE; HUMANS; MALE; MARITAL STATUS; MODELS, STATISTICAL; SCHIZOPHRENIA; SEX DISTRIBUTION; SUBSTANCE-RELATED DISORDERS; YOUNG ADULT;

EID: 84887065145     PISSN: 01638343     EISSN: 18737714     Source Type: Journal    
DOI: 10.1016/j.genhosppsych.2013.07.002     Document Type: Article

References (21)

1. DeLisi L.E. The significance of age of onset for schizophrenia. Schizophr Bull 1992, 18(2):209-215.
2. Ongür D., Lin L., Cohen B.M. Clinical characteristics influencing age at onset in psychotic disorders. Compr Psychiatry 2009, 50:13-19.
3. De Hert M., Wampers M., Jendricko T., et al. Effects of cannabis use on age at onset in schizophrenia and bipolar disorder. Schizophr Res 2011, 126:270-276.
4. Esterberg M.L., Trotman H.D., Holtzman C., et al. The impact of a family history of psychosis on age-at-onset and positive and negative symptoms of schizophrenia: a meta-analysis. Schizophr Res 2010, 120:121-130.
5. Rabinowitz J., Levine S.Z., Häfner H. A population based elaboration of the role of age of onset on the course of schizophrenia. Schizophr Res 2006, 88(1-3):96-101.
6. Häfner H., an der Heiden W., Behrens S., Gattaz W.F., Hambrecht M., Löffler W., et al. Causes and consequences of the gender difference in age at onset of schizophrenia. Schizophr Bull 1998, 24(1):99-113.
7. Luoma S., Hakko H., Ollinen T., et al. Association between age at onset and clinical features of schizophrenia: the Northern Finland 1966 birth cohort study. Eur Psychiatry 2008, 23:331-335.
8. Mattai A.K., Hill J.L., Lenroot R.K. Treatment of early-onset schizophrenia. Curr Opin Psychiatry 2010, 23:304-310.
9. Schürhoff F., Golmard J.L., Szoke A., et al. Admixture analysis of age at onset in schizophrenia. Schizophr Res 2004, 71:35-41.
10. Hollis C. Adolescent schizophrenia. Adv Psychiatry 2000, 6:83-92.
11. Panariello F., O'Driscoll L., de Souza R.P., et al. Age at onset in Canadian schizophrenia patients: admixture analysis. Schizophr Res 2010, 122:278-279.
12. Vinokur D., Levine S.Z., Roe D., Krivoy A., Fischel T. Age of onset group characteristics in forensic patients with schizophrenia. Eur Psychiatry. 2013, doi:pii: S0924-9338(12)00142-3. 10.1016/j.eurpsy.2012.11.006. [Epub ahead of print].
13. Norman R.M., Malla A.K., Manchanda R., et al. Does treatment delay predict occupational functioning in first-episode psychosis?. Schizophr Res 2007, 91:259-262.
14. Prevention and early intervention program for psychoses. PEPP screening and assessment manual (part 1) [Internet]. London (ON): PEPP; [cited 2012 Jul 29]. Available from: http://pepp.ca/images/pmodule1.pdf.
15. Norman R.M.G., Malla A.K. Course of onset and relapse schedule: interview and coding instruction guide 2002, Prevention and early intervention program for psychoses, London.
16. Häfner H., Riecher-Rössler A., Hambrecht M., et al. IRAOS: an instrument for the assessment of onset and early course of schizophrenia. Schizophr Res 1992, 6:209-223.
17. Javaid N., Kennedy J.L., De Luca V. Ethnicity and age at onset in bipolar spectrum disorders. CNS Spectr 2011, 16:6.
18. Hambrecht M., Hafner H. Cannabis, vulnerability, and the onset of schizophrenia: an epidemiological perspective. Aust N Z J Psychiatry 2000, 34:468-475.
19. Gureje O., Bamidele R.W. Gender and schizophrenia: association of age at onset with antecedent, clinical and outcome features. Aust N Z J Psychiatry 1998, 32:415-423.
20. Häfner H., Hambrecht M., Löffler W., et al. Is schizophrenia a disorder of all ages? A comparison of first episodes and early course across the life-cycle. Psychol Med 1998, 28:351-365.
21. Delorme R., Golmard J., Chabane N., et al. Admixture analysis of age at onset in obsessive-compulsive disorder. Psychol Med 2005, 35:237-243.