Genome-wide analysis of body proportion classifies height-associated variants by mechanism of action and implicates genes important for skeletal development

American Journal of Human Genetics

Volumn 96, Issue 5, 2015, Pages 695-708

  Chan, Yingleong ^a,b,c   Salem, Rany M ^a,b,c   Hsu, Yu Han H ^a,b,c   McMahon, George ^d   Pers, Tune H ^a,b,c   Vedantam, Sailaja ^b,c   Esko, Tonu ^a,b,c,e   Guo, Michael H ^a,b,c   Lim, Elaine T ^a,b,c   Franke, Lude ^f   Smith, George Davey ^d   Strachan, David P ^g   Hirschhorn, Joel N ^a,b,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD UNIVERSITY   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

^e UNIVERSITY OF TARTU   (Estonia)

^f UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^g ST GEORGE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN BINDING PROTEIN 3; TRANSCRIPTION FACTOR T BET;

ADULT; AFRICAN AMERICAN; ALLELE; ANALYSIS; ANCESTRY GROUP; ANTHROPOMETRIC PARAMETERS; ARTICLE; BODY HEIGHT; BONE; BONE DEVELOPMENT; CARTILAGE; EMBRYO DEVELOPMENT; ENHANCER ENRICHMENT ANALYSIS; EUROPEAN; EUROPEAN AMERICAN; FEMALE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; GROWTH PLATE; HEAD LENGTH; HEREDITY; HERITABILITY; HUMAN; LEG LENGTH; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MULTIFACTORIAL INHERITANCE; PRIORITY JOURNAL; RATIO OF SITTING HEIGHT TO TOTAL HEIGHT; SINGLE NUCLEOTIDE POLYMORPHISM; SITTING HEIGHT RATIO; SPIN LENGTH; CAUCASIAN; CHROMOSOME MAP; GENETICS; GROWTH, DEVELOPMENT AND AGING; LEG; PHENOTYPE;

ADULT; AFRICAN AMERICANS; BODY HEIGHT; CHROMOSOME MAPPING; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LEG BONES; MALE; MIDDLE AGED; MULTIFACTORIAL INHERITANCE; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84929267622     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2015.02.018     Document Type: Article

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