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Volumn 2014, Issue , 2014, Pages

Lenalidomide Induces Immunomodulation in Chronic Lymphocytic Leukemia and Enhances Antitumor Immune Responses Mediated by NK and CD4 T Cells

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; INTERLEUKIN 2; LENALIDOMIDE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; RITUXIMAB; ANTINEOPLASTIC AGENT; THALIDOMIDE;

EID: 84929235609     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/265840     Document Type: Article
Times cited : (53)

References (30)
  • 3
    • 33646755569 scopus 로고    scopus 로고
    • Cancer immunosurveillance and immunoediting: The roles of immunity in suppressing tumor development and shaping tumor immunogenicity
    • M. J. Smyth, G. P. Dunn, and R. D. Schreiber, "Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity, " Advances in Immunology, vol. 90, pp. 1-50, 2006.
    • (2006) Advances in Immunology , vol.90 , pp. 1-50
    • Smyth, M.J.1    Dunn, G.P.2    Schreiber, R.D.3
  • 4
    • 10844263473 scopus 로고    scopus 로고
    • Vδ1 T lymphocytes fromB-CLL patients recognizeULBP3 expressed on leukemic B cells and up-regulated by trans-retinoic acid
    • A. Poggi, C. Venturino, S. Catellani et al., "Vδ1 T lymphocytes fromB-CLL patients recognizeULBP3 expressed on leukemic B cells and up-regulated by trans-retinoic acid, " Cancer Research, vol. 64, no. 24, pp. 9172-9179, 2004.
    • (2004) Cancer Research , vol.64 , Issue.24 , pp. 9172-9179
    • Poggi, A.1    Venturino, C.2    Catellani, S.3
  • 5
    • 77957727208 scopus 로고    scopus 로고
    • Prognostic significance of CD8 and CD4 T cells in chronic lymphocytic leukemia
    • A. P. Gonzalez-Rodriguez, J. Contesti, L. Huergo-Zapico et al., "Prognostic significance of CD8 and CD4 T cells in chronic lymphocytic leukemia, " Leukemia & Lymphoma, vol. 51, no. 10, pp. 1829-1836, 2010.
    • (2010) Leukemia & Lymphoma , vol.51 , Issue.10 , pp. 1829-1836
    • Gonzalez-Rodriguez, A.P.1    Contesti, J.2    Huergo-Zapico, L.3
  • 6
    • 51749087317 scopus 로고    scopus 로고
    • The immunodeficiency of chronic lymphocytic leukaemia
    • A. D. Hamblin and T. J. Hamblin, "The immunodeficiency of chronic lymphocytic leukaemia, " The British Medical Bulletin, vol. 87, no. 1, pp. 49-62, 2008.
    • (2008) The British Medical Bulletin , vol.87 , Issue.1 , pp. 49-62
    • Hamblin, A.D.1    Hamblin, T.J.2
  • 7
    • 16444363534 scopus 로고    scopus 로고
    • Cellular and molecular signal transduction pathways modulated by rituximab (rituxan, anti-CD20 mAb) in non-Hodgkins lymphoma: Implications in chemosensitization and therapeutic intervention
    • A. R. Jazirehi and B. Bonavida, "Cellular and molecular signal transduction pathways modulated by rituximab (rituxan, anti-CD20 mAb) in non-Hodgkins lymphoma: Implications in chemosensitization and therapeutic intervention, " Oncogene, vol. 24, no. 13, pp. 2121-2143, 2005.
    • (2005) Oncogene , vol.24 , Issue.13 , pp. 2121-2143
    • Jazirehi, A.R.1    Bonavida, B.2
  • 8
    • 23844435619 scopus 로고    scopus 로고
    • Immunomodulatory drug CC-5013 or CC-4047 and rituximab enhance antitumor activity in a severe combined immunodeficient mouse lymphoma model
    • F. J. Hernandez-Ilizaliturri, N. Reddy, B. Holkova, E. Ottman, and M. S. Czuczman, "Immunomodulatory drug CC-5013 or CC-4047 and rituximab enhance antitumor activity in a severe combined immunodeficient mouse lymphoma model, " Clinical Cancer Research, vol. 11, no. 16, pp. 5984-5992, 2005.
    • (2005) Clinical Cancer Research , vol.11 , Issue.16 , pp. 5984-5992
    • Hernandez-Ilizaliturri, F.J.1    Reddy, N.2    Holkova, B.3    Ottman, E.4    Czuczman, M.S.5
  • 9
    • 33750607347 scopus 로고    scopus 로고
    • A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma
    • P. G. Richardson, E. Blood, C. S. Mitsiades et al., "A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma, " Blood, vol. 108, no. 10, pp. 3458-3464, 2006.
    • (2006) Blood , vol.108 , Issue.10 , pp. 3458-3464
    • Richardson, P.G.1    Blood, E.2    Mitsiades, C.S.3
  • 10
    • 13444256401 scopus 로고    scopus 로고
    • Efficacy of lenalidomide in myelodysplastic syndromes
    • A. List, S. Kurtin, D. J. Roe et al., "Efficacy of lenalidomide in myelodysplastic syndromes, " The New England Journal of Medicine, vol. 352, no. 6, pp. 549-557, 2005.
    • (2005) The New England Journal of Medicine , vol.352 , Issue.6 , pp. 549-557
    • List, A.1    Kurtin, S.2    Roe, D.J.3
  • 11
    • 33947243663 scopus 로고    scopus 로고
    • Clinical efficacy of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia: Results of a phase II study
    • A. Chanan-Khan, K. C. Miller, L. Musial et al., "Clinical efficacy of lenalidomide in patients with relapsed or refractory chronic lymphocytic leukemia: results of a phase II study, " Journal of Clinical Oncology, vol. 24, no. 34, pp. 5343-5349, 2006.
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.34 , pp. 5343-5349
    • Chanan-Khan, A.1    Miller, K.C.2    Musial, L.3
  • 12
    • 74949083498 scopus 로고    scopus 로고
    • Efficacy of lenalidomide in patients with chronic lymphocytic leukemia with high-risk cytogenetics
    • T. Sher, K. C. Miller, D. Lawrence et al., "Efficacy of lenalidomide in patients with chronic lymphocytic leukemia with high-risk cytogenetics, " Leukemia and Lymphoma, vol. 51, no. 1, pp. 85-88, 2010.
    • (2010) Leukemia and Lymphoma , vol.51 , Issue.1 , pp. 85-88
    • Sher, T.1    Miller, K.C.2    Lawrence, D.3
  • 13
    • 45949100928 scopus 로고    scopus 로고
    • Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia
    • A. Ferrajoli, B. N. Lee, E. J. Schlette et al., "Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia, " Blood, vol. 111, no. 11, pp. 5291-5297, 2008.
    • (2008) Blood , vol.111 , Issue.11 , pp. 5291-5297
    • Ferrajoli, A.1    Lee, B.N.2    Schlette, E.J.3
  • 15
    • 34447292863 scopus 로고    scopus 로고
    • Multiple myeloma: A prototypic disease model for the characterization and therapeutic targeting of interactions between tumor cells and their local microenvironment
    • C. S. Mitsiades, N. S. Mitsiades, P. G. Richardson, N. C. Munshi, and K. C. Anderson, "Multiple myeloma: a prototypic disease model for the characterization and therapeutic targeting of interactions between tumor cells and their local microenvironment, " Journal of Cellular Biochemistry, vol. 101, no. 4, pp. 950-968, 2007.
    • (2007) Journal of Cellular Biochemistry , vol.101 , Issue.4 , pp. 950-968
    • Mitsiades, C.S.1    Mitsiades, N.S.2    Richardson, P.G.3    Munshi, N.C.4    Anderson, K.C.5
  • 16
    • 34547474047 scopus 로고    scopus 로고
    • Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q-syndrome patients
    • A. Pellagatti, M. Jadersten, A.-M. Forsblom et al., "Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q-syndrome patients, " Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 27, pp. 11406-11411, 2007.
    • (2007) Proceedings of the National Academy of Sciences of the United States of America , vol.104 , Issue.27 , pp. 11406-11411
    • Pellagatti, A.1    Jadersten, M.2    Forsblom, A.-M.3
  • 17
    • 80055021878 scopus 로고    scopus 로고
    • Biological effects and clinical significance of lenalidomide-induced tumour flare reaction in patients with chronic lymphocytic leukaemia: In vivo evidence of immune activation and antitumour response
    • A. A. Chanan-Khan, K. Chitta, N. Ersing et al., "Biological effects and clinical significance of lenalidomide-induced tumour flare reaction in patients with chronic lymphocytic leukaemia: in vivo evidence of immune activation and antitumour response, " British Journal of Haematology, vol. 155, no. 4, pp. 457-467, 2011.
    • (2011) British Journal of Haematology , vol.155 , Issue.4 , pp. 457-467
    • Chanan-Khan, A.A.1    Chitta, K.2    Ersing, N.3
  • 18
    • 70349150560 scopus 로고    scopus 로고
    • Lenalidomide-induced upregulation of CD80 on tumor cells correlates with T-cell activation, the rapid onset of a cytokine release syndrome and leukemic cell clearance in chronic lymphocytic leukemia
    • G. Aue, N. Njuguna, X. Tian et al., "Lenalidomide-induced upregulation of CD80 on tumor cells correlates with T-cell activation, the rapid onset of a cytokine release syndrome and leukemic cell clearance in chronic lymphocytic leukemia, " Haematologica, vol. 94, no. 9, pp. 1266-1273, 2009.
    • (2009) Haematologica , vol.94 , Issue.9 , pp. 1266-1273
    • Aue, G.1    Njuguna, N.2    Tian, X.3
  • 19
    • 80051928145 scopus 로고    scopus 로고
    • Treatmentwith lenalidomide modulates T-cell immunophenotype and cytokine production in patients with chronic lymphocytic leukemia
    • B.-N. Lee, H. Gao, E. N. Cohen et al., "Treatmentwith lenalidomide modulates T-cell immunophenotype and cytokine production in patients with chronic lymphocytic leukemia, " Cancer, vol. 117, no. 17, pp. 3999-4008, 2011.
    • (2011) Cancer , vol.117 , Issue.17 , pp. 3999-4008
    • Lee, B.-N.1    Gao, H.2    Cohen, E.N.3
  • 20
    • 33745961875 scopus 로고    scopus 로고
    • Enhancement of ligand-dependent activation of human natural killer T cells by lenalidomide: Therapeutic implications
    • D. H. Chang, N. Liu, V. Klimek et al., "Enhancement of ligand-dependent activation of human natural killer T cells by lenalidomide: Therapeutic implications, " Blood, vol. 108, no. 2, pp. 618-621, 2006.
    • (2006) Blood , vol.108 , Issue.2 , pp. 618-621
    • Chang, D.H.1    Liu, N.2    Klimek, V.3
  • 22
    • 46749132717 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug
    • A. G. Ramsay, A. J. Johnson, A. M. Lee et al., "Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug, " Journal of Clinical Investigation, vol. 118, no. 7, pp. 2427-2437, 2008.
    • (2008) Journal of Clinical Investigation , vol.118 , Issue.7 , pp. 2427-2437
    • Ramsay, A.G.1    Johnson, A.J.2    Lee, A.M.3
  • 23
    • 74949135128 scopus 로고    scopus 로고
    • Thalidomide and lenalidomide as new therapeutics for the treatment of chronic lymphocytic leukemia
    • F. T. Awan, A. J. Johnson, R. Lapalombella et al., "Thalidomide and lenalidomide as new therapeutics for the treatment of chronic lymphocytic leukemia, " Leukemia and Lymphoma, vol. 51, no. 1, pp. 27-38, 2010.
    • (2010) Leukemia and Lymphoma , vol.51 , Issue.1 , pp. 27-38
    • Awan, F.T.1    Johnson, A.J.2    Lapalombella, R.3
  • 24
    • 69949096727 scopus 로고    scopus 로고
    • Mechanism of action of lenalidomide in hematological malignancies
    • article 36
    • V. Kotla, S. Goel, S. Nischal et al., "Mechanism of action of lenalidomide in hematological malignancies, " Journal of Hematology and Oncology, vol. 2, no. 12, article 36, 2009.
    • (2009) Journal of Hematology and Oncology , vol.2 , Issue.12
    • Kotla, V.1    Goel, S.2    Nischal, S.3
  • 25
    • 51649123319 scopus 로고    scopus 로고
    • Lenalidomide enhances natural killer cell andmonocyte-mediated antibody-dependent cellular cytotoxicity of rituximab-treated CD20+ tumor cells
    • L. Wu, M. Adams, T. Carter et al., "Lenalidomide enhances natural killer cell andmonocyte-mediated antibody-dependent cellular cytotoxicity of rituximab-treated CD20+ tumor cells, " Clinical Cancer Research, vol. 14, no. 14, pp. 4650-4657, 2008.
    • (2008) Clinical Cancer Research , vol.14 , Issue.14 , pp. 4650-4657
    • Wu, L.1    Adams, M.2    Carter, T.3
  • 26
    • 50349083290 scopus 로고    scopus 로고
    • Lenalidomide enhances tumor killing in vitro during ADCC mediated by Trastuzumab, Cetuximab, and Rituximab
    • J. B. Bartlett, "Lenalidomide enhances tumor killing in vitro during ADCC mediated by Trastuzumab, Cetuximab, and Rituximab, " Journal of Clinical Oncology, vol. 25, p. 3023, 2007.
    • (2007) Journal of Clinical Oncology , vol.25 , pp. 3023
    • Bartlett, J.B.1
  • 27
    • 79955515528 scopus 로고    scopus 로고
    • Tumor flare reaction associated with lenalidomide treatment in patients with chronic lymphocytic leukemia predicts clinical response
    • A. Chanan-Khan, K. C. Miller, D. Lawrence et al., "Tumor flare reaction associated with lenalidomide treatment in patients with chronic lymphocytic leukemia predicts clinical response, " Cancer, vol. 117, no. 10, pp. 2127-2135, 2011.
    • (2011) Cancer , vol.117 , Issue.10 , pp. 2127-2135
    • Chanan-Khan, A.1    Miller, K.C.2    Lawrence, D.3
  • 28
    • 45149100665 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: A report from the international workshop on chronic lymphocytic leukemia updating the national cancer institute-working group 1996 guidelines
    • M. Hallek, B. D. Cheson, D. Catovsky et al., "Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the international workshop on chronic lymphocytic leukemia updating the national cancer institute-working group 1996 guidelines, " Blood, vol. 111, no. 12, pp. 5446-5456, 2008.
    • (2008) Blood , vol.111 , Issue.12 , pp. 5446-5456
    • Hallek, M.1    Cheson, B.D.2    Catovsky, D.3
  • 29
    • 19944430437 scopus 로고    scopus 로고
    • Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: Clinical application
    • T. Hayashi, T. Hideshima, M. Akiyama et al., "Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application, " The British Journal of Haematology, vol. 128, no. 2, pp. 192-203, 2005.
    • (2005) The British Journal of Haematology , vol.128 , Issue.2 , pp. 192-203
    • Hayashi, T.1    Hideshima, T.2    Akiyama, M.3
  • 30
    • 67649979853 scopus 로고    scopus 로고
    • HDAC3 represses the expression of NKG2D ligands ULBPs in epithelial tumour cells: Potential implications for the immunosurveillance of cancer
    • A. Lopez-Soto, A. R. Folgueras, E. Seto, and S. Gonzalez, "HDAC3 represses the expression of NKG2D ligands ULBPs in epithelial tumour cells: potential implications for the immunosurveillance of cancer, " Oncogene, vol. 28, no. 25, pp. 2370-2382, 2009.
    • (2009) Oncogene , vol.28 , Issue.25 , pp. 2370-2382
    • Lopez-Soto, A.1    Folgueras, A.R.2    Seto, E.3    Gonzalez, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.