Morphine may enhance the cardioprotection induced by remote ischemic perconditioning

International Journal of Cardiology

Volumn 187, Issue 1, 2015, Pages 443-444

  Lu, Yao ^a   Hu, Jun ^b   Dong, Chunshan ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b Tongling People's Hospital of Anhui Province   (China)

Author keywords

Ischemia reperfusion injury; Morphine; Perconditioning

Indexed keywords

ANGIOTENSIN II; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MORPHINE; PROTEIN TYROSINE KINASE; STAT5 PROTEIN; TROPONIN I;

APOPTOSIS; CARDIOVASCULAR PROCEDURE; GENERAL PATHOLOGICAL PARAMETERS; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HUMAN; INFARCT SIZE; INTRACELLULAR SIGNALING; LETTER; MOLECULAR DYNAMICS; NONHUMAN; OXIDATIVE STRESS; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; PROTEIN FUNCTION; REMOTE ISCHEMIC PERCONDITIONING; REPERFUSION INJURY; RISK PATHWAY; SIGNAL TRANSDUCTION; ST SEGMENT; TRANSIENT CAROTID ISCHEMIA; ANIMAL; CAROTID ARTERY; HEART INFARCTION PREVENTION; INTRACELLULAR FLUID; MALE; METABOLISM; PHYSIOLOGY; PROCEDURES;

ANIMALS; CAROTID ARTERIES; INTRACELLULAR FLUID; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALE; MYOCARDIAL INFARCTION; SIGNAL TRANSDUCTION;

EID: 84929213263     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2015.03.363     Document Type: Article

References (7)

1. I. Andreadou, S.I. Bibli, E. Mastromanolis, et al., Transient carotid ischemia as a remote conditioning stimulus for myocardial protection in anesthetized rabbits: insights into intracellular signaling, Int. J. Cardiol. 184C (2015) 140-151.
2. M.R. Schmidt, M. Smerup, I.E. Konstantinov, et al., Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning, Am. J. Physiol. Heart Circ. Physiol. 292 (2007) H1883-H1890.
3. E.R. Gross, A.K. Hsu, G.J. Gross, Opioid-induced cardioprotection occurs via glycogen synthase kinase beta inhibition during reperfusion in intact rat hearts, Circ. Res. 94 (2004) 960-966.
4. I. Rentoukas, G. Giannopoulos, A. Kaoukis, et al., Cardioprotective role of remote ischemic periconditioning in primary percutaneous coronary intervention: enhancement by opioid action, JACC Cardiovasc. Interv. 3 (2010) 49-55.
5. Y. Lu, C.S. Dong, J.M. Yu, et al., Morphine reduces the threshold of remote ischemic preconditioning against myocardial ischemia and reperfusion injury in rats: the role of opioid receptors, J. Cardiothorac. Vasc. Anesth. 26 (2012) 403-406.
6. Y.C. Xu, F.S. Xue, X. Liao, et al., Combined morphine and limb remote ischaemia postconditioning may produce an enhanced cardioprotection, Med. Hypotheses 73 (2009) 302-305.
7. S. de Zeeuw, T.W. Lameris, D.J. Duncker, et al., Cardioprotection in pigs by exogenous norepinephrine but not by cerebral ischemia-induced release of endogenous norepinephrine, Stroke 32 (2001) 767-774.