Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: First demonstration of remote ischemic perconditioning

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 292, Issue 4, 2007, Pages

  Schmidt, M R ^a,b   Smerup, M ^a   Konstantinov, I E ^b   Shimizu, M ^b   Li, J ^b   Cheung, M ^b   White, P A ^c   Kristiansen, S B ^a   Sorensen, K ^a   Dzavik, V ^d   Redington, A N ^b   Kharbanda, R K ^c,d,e  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c PAPWORTH HOSPITAL   (United Kingdom)

^d UNIVERSITY HEALTH NETWORK   (Canada)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Cardioprotection; Remote preconditioning

Indexed keywords

ADENOSINE TRIPHOSPHATE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; HEART ARRHYTHMIA; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART RATE; HEART VENTRICLE ENDDIASTOLIC PRESSURE; ISCHEMIA; LIMB ISCHEMIA; NONHUMAN; PRIORITY JOURNAL; REPERFUSION; SWINE; SYSTOLIC BLOOD PRESSURE;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIA; BODY TEMPERATURE; ELECTRIC COUNTERSHOCK; EXTREMITIES; GLYBURIDE; ISCHEMIA; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; POTASSIUM CHANNELS; SUS SCROFA; TOURNIQUETS; VENTRICULAR FUNCTION, LEFT; VENTRICULAR PRESSURE;

EID: 34147172678     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00617.2006     Document Type: Article

References (30)

1. Addison PD, Neligan PC, Ashrafpour H, Khan A, Zhong A, Moses M, Forrest CR, Pang CY. Noninvasive remote ischemic preconditioning for global protection of skeletal muscle against infarction. Am J Physiol Heart Circ Physiol 285: H1435-H1443, 2003.
2. Birnbaum Y, Hale SL, Kloner RA. Ischemic preconditioning at a distance: reduction of myocardial infarct size by partial reduction of blood supply combined with rapid stimulation of the gastrocnemius muscle in the rabbit. Circulation 96: 1641-1646, 1997.
3. Cheung MM, Konstantinov IE, Kharbanda R, Redington A. Remote ischemic preconditioning reduces myocardial injury in children undergoing open heart surgery. Circulation 110: S568-S569, 2004.
4. Dawson JR, Gibson DG. Left ventricular filling and early diastolic function at rest and during angina in patients with coronary artery disease. Br Heart J 61: 248-257, 1989.
5. Gho BC, Schoemaker RG, van den Doel MA, Duncker DJ, Verdouw PD. Myocardial protection by brief ischemia in noncardiac tissue. Circulation 94: 2193-2200, 1996.
6. Gunaydin B, Cakici I, Soncul H, Kalaycioglu S, Cevik C, Sancak B, Kanzik I, Karadenizli Y. Does remote organ ischaemia trigger cardiac preconditioning during coronary artery surgery? Pharmacol Res 41: 493-496, 2000.
7. Heusch G. Postconditioning: old wine in a new bottle? J Am Coll Cardiol 44: 1111-1112, 2004.
8. Kerendi F, Kin H, Halkos ME, Jiang R, Zatta AJ, Zhao ZQ, Guyton RA, Vinten-Johansen J. Remote postconditioning. Brief renal ischemia and reperfusion applied before coronary artery reperfusion reduces myocardial infarct size via endogenous activation of adenosine receptors. Basic Res Cardiol 100: 404-412, 2005.
9. Kharbanda RK, Mortensen UM, White PA, Kristiansen SB, Schmidt MR, Hoschtitzky JA, Vogel M, Sorensen K, Redington AN, MacAllister R. Transient limb ischemia induces remote ischemic preconditioning in vivo. Circulation 106: 2881-2883, 2002.
10. Konstantinov IE, Arab S, Kharbanda RK, Li J, Cheung MM, Cherepanov V, Downey GP, Liu PP, Cukerman E, Coles JG, Redington AN. The remote ischemic preconditioning stimulus modifies inflammatory gene expression in humans. Physiol Genomics 19: 143-150, 2004.
11. ATP channel-dependent mechanism. Transplantation 79: 1691-1695, 2005.
12. ATP channel-dependent mechanism. Am J Physiol Heart Circ Physiol 288: H1252-H1256, 2005.
13. Liem DA, Verdouw PD, Ploeg H, Kazim S, Duncker DJ. Sites of action of adenosine in interorgan preconditioning of the heart. Am J Physiol Heart Circ Physiol 283: H29-H37, 2002.
14. Loukogeorgakis SP, Panagiotidou AT, Broadhead MW, Donald A, Deanfield JE, MacAllister RJ. Remote ischemic preconditioning provides early and late protection against endothelial ischemia-reperfusion injury in humans: role of the autonomic nervous system. J Am Coll Cardiol 46: 450-456, 2005.
15. Mahaffey KW, Granger CB, Nicolau JC, Ruzyllo W, Weaver WD, Theroux P, Hochman JS, Filloon TG, Mojcik CF, Todaro TG, Armstrong PW. Effect of pexelizumab, an anti-C5 complement antibody, as adjunctive therapy to fibrinolysis in acute myocardial infarction: the COMPlement inhibition in myocardial infarction treated with thromboLYtics (COMPLY) trial. Circulation 108: 1176-1183, 2003.
16. Mehta SR, Yusuf S, Diaz R, Zhu J, Pais P, Xavier D, Paolasso E, Ahmed R, Xie C, Kazmi K, Tai J, Orlandini A, Pogue J, Liu L. Effect of glucose-insulin-potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction: the CREATE-ECLA randomized controlled trial. JAMA 293: 437-446, 2005.
17. ATP channels in hindlimb remote ischemic preconditioning of skeletal muscle against infarction. Am J Physiol Heart Circ Physiol 288: H559-H567, 2005.
18. Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74: 1124-1136, 1986.
19. Ovize M, Aupetit JF, Rioufol G, Loufoua J, Andre-Fouet X, Minaire Y, Faucon G. Preconditioning reduces infarct size but accelerates time to ventricular fibrillation in ischemic pig heart. Am J Physiol Heart Circ Physiol 269: H72-H79, 1995.
20. Pell TJ, Baxter GF, Yellon DM, Drew GM. Renal ischemia preconditions myocardium: role of adenosine receptors and ATP-sensitive potassium channels. Am J Physiol Heart Circ Physiol 275: H1542-H1547, 1998.
21. Piper HM, Meuter K, Schafer C. Cellular mechanisms of ischemia-reperfusion injury. Ann Thorac Surg 75: S644-S648, 2003.
22. Przyklenk K, Darling CE, Dickson EW, Whittaker P. Cardioprotection "outside the box" - the evolving paradigm of remote preconditioning. Basic Res Cardiol 98: 149-157, 2003.
23. Schmidt MR, Kristiansen SB, White P, Smerup M, Botker HE, Vogel M, Hjortdal V, Sorensen K, Redington A. Glucose-insulin infusion improves cardiac function during fetal tachycardia. J Am Coll Cardiol 43: 445-452, 2004.
24. Schulz R, Rose J, Heusch G. Involvement of activation of ATP-dependent potassium channels in ischemic preconditioning in swine. Am J Physiol Heart Circ Physiol 267: H1341-H1352, 1994.
25. Staat P, Rioufol G, Piot C, Cottin Y, Cung TT, L'Huillier I, Aupetit JF, Bonnefoy E, Finet G, Andre-Fouet X, Ovize M. Postconditioning the human heart. Circulation 112: 2143-2148, 2005.
26. Theroux P, Chaitman BR, Danchin N, Erhardt L, Meinertz T, Schroeder JS, Tognoni G, White HD, Willerson JT, Jessel A. Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations. Main results of the GUARDIAN trial Guard During Ischemia Against Necrosis (GUARDIAN) Investigators. Circulation 102: 3032-3038, 2000.
27. Vassalle M, Lin CI. Calcium overload and cardiac function. J Biomed Sci 11: 542-565, 2004.
28. Vinten-Johansen J, Yellon DM, Opie LH. Postconditioning: a simple, clinically applicable procedure to improve revascularization in acute myocardial infarction. Circulation 112: 2085-2088, 2005.
29. Wu ZK, Iivainen T, Pehkonen E, Laurikka J, Tarkka MR. Ischemic preconditioning suppresses ventricular tachyarrhythmias after myocardial revascularization. Circulation 106: 3091-3096, 2002.
30. Zhao ZQ, Corvera JS, Halkos ME, Kerendi F, Wang NP, Guyton RA, Vinten-Johansen J. Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning. Am J Physiol Heart Circ Physiol 285: H579-H588, 2003.