Neuronal hyperactivity accelerates depletion of neural stem cells and impairs hippocampal neurogenesis

Cell Stem Cell

Volumn 16, Issue 5, 2015, Pages 488-503

  Sierra, Amanda ^a,b,c   Martín Suárez, Soraya ^a   Valcárcel Martín, Roberto ^a   Pascual Brazo, Jesús ^e   Aelvoet, Sarah Ann ^d   Abiega, Oihane ^a   Deudero, Juan J ^e   Brewster, Amy L ^e   Bernales, Irantzu ^c   Anderson, Anne E ^e   Baekelandt, Veerle ^d   Maletić Savatić, Mirjana ^e   Encinas, Juan M ^a,b,c  

^a ACHUCARRO BASQUE CENTER FOR NEUROSCIENCE   (Spain)

^b BASQUE FOUNDATION FOR SCIENCE   (Spain)

^c UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^d UNIVERSITY OF LEUVEN   (Belgium)

^e TEXAS CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KAINIC ACID;

ADULT; AGING; ANIMAL CELL; ARTICLE; ASTROCYTE; CELL ACTIVATION; CELL FUNCTION; CELL PROLIFERATION; CELL RENEWAL; CELLULAR PARAMETERS; DAUGHTER CELL; DENTATE GYRUS; ELECTRODE IMPLANTATION; ELECTROENCEPHALOGRAPHY; EPILEPSY; EPILEPTIC DISCHARGE; HIPPOCAMPUS; HYPERACTIVITY; INFLAMMATION; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEURAL STEM CELL DEPLETION; NEURONAL HYPERACTIVITY; NONHUMAN; PRIORITY JOURNAL; SEIZURE; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; CYTOLOGY; DISEASE MODEL; HUMAN; PATHOPHYSIOLOGY; PHYSIOLOGY; RESTLESSNESS;

ADULT; ANIMALS; ASTROCYTES; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EPILEPSY; HIPPOCAMPUS; HUMANS; KAINIC ACID; MICE; MICE, INBRED C57BL; NEURAL STEM CELLS; NEUROGENESIS; PSYCHOMOTOR AGITATION;

EID: 84929167162     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2015.04.003     Document Type: Article

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