Composite alginate and gelatin based bio-polymeric wafers containing silver sulfadiazine for wound healing

International Journal of Biological Macromolecules

Volumn 79, Issue , 2015, Pages 63-71

  Boateng, Joshua ^a   Burgos Amador, Rocio ^a   Okeke, Obinna ^a   Pawar, Harshavardhan ^a  

^a UNIVERSITY OF GREENWICH   (United Kingdom)

Author keywords

Bio polymeric; Wafers; Wound healing

Indexed keywords

ALGINIC ACID; AMIDE; BIOPOLYMER; GELATIN; POLYMER; SULFADIAZINE SILVER; UNCLASSIFIED DRUG; WAFER; DELAYED RELEASE FORMULATION; GLUCURONIC ACID; HEXURONIC ACID;

ARTICLE; CHRONIC WOUND; COMPOSITE MATERIAL; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG SOLUBILITY; FREEZE DRYING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDRATION; HYDROGEN BOND; IN VITRO STUDY; INFRARED SPECTROSCOPY; MECHANICAL HARDNESS; MOLECULAR INTERACTION; MUCOADHESION; PHYSICAL CHEMISTRY; PHYSICAL PARAMETERS; SCANNING ELECTRON MICROSCOPY; STATIC ELECTRICITY; WOUND HEALING; X RAY DIFFRACTION; CHEMICAL MODEL; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG EFFECTS; DRUG FORMULATION; DRUG RELEASE; HARDNESS; HUMAN; KINETICS;

BACTERIA (MICROORGANISMS);

ALGINATES; BIOPOLYMERS; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; DRUG LIBERATION; FREEZE DRYING; GELATIN; GLUCURONIC ACID; HARDNESS; HEXURONIC ACIDS; HUMANS; HYDROGEN BONDING; KINETICS; MODELS, CHEMICAL; SILVER SULFADIAZINE; STATIC ELECTRICITY; WOUND HEALING;

EID: 84929104452     PISSN: 01418130     EISSN: 18790003     Source Type: Journal    
DOI: 10.1016/j.ijbiomac.2015.04.048     Document Type: Article

References (34)

1. Mogoşanua G.D., Grumezescu A.M. Natural and synthetic polymers for wounds and burns dressing. Int. J. Pharm. 2014, 463:127-136.
2. Pawar H.V., Tetteh J., Boateng J.S. Preparation, optimization and characterization of novel wound healing film dressings loaded with streptomycin and diclofenac. Colloids Surf., B: Biointerfaces 2013, 102:102-110.
3. Pawar H.V., Tetteh J., Boateng J.S. Multi functional medicated lyophilized wafer dressing for effective chronic wound healing. J. Pharm. Sci. 2014, 103(6):1720-1733.
4. Pereira R., Carvalho A., Vaz D.C., Gil M.H., Mendes A., Bártolo P. Development of novel alginate based hydrogel films for wound healing applications. Int. J. Biol. Macromol. 2013, 52:221-230.
5. Thomas A., Harding K.G., Moore K. Alginates from wound dressings activate human macrophages to secrete tumor necrosis factor-α. Biomaterials 2000, 21:1797-1802.
6. Boateng J.S., Matthews K.H., Stevens H.N.E., Eccleston G.M. Wound healing dressings and drug delivery systems: a review. J. Pharm. Sci. 2008, 97(8):2892-2923.
7. Saarai A., Kasparkova V., Sedlacek T., Saha P.A. Comparative study of crosslinked sodium alginate/gelatin hydrogels for wound dressing. Recent Researches in Geography Geology, Energy, Environment and Biomedicine 2011, 384-389. WSEAS Press, Greece. N. Mastorakis (Ed.).
8. + effects on multi-functional alginate dressings. Carbohydr. Polym. 2012, 87(2):1796-1802.
9. Moura L.I.F., Dias A.M.A., Carvalho E., de Sousa H.C. Recent advances on the development of wound dressings for diabetic foot ulcer treatment-a review. Acta Biomater. 2013, 9:7093-7114.
10. Panouille M., Larreta-Garde V. Gelation behavior of gelatin and alginate mixtures. Food Hydrocoll. 2008, 23:1074-1080.
11. Saarai A., Kasparkova V., Sedlacek A.T., Saha P. On the development and characterization of crosslinked sodium alginate/gelatin hydrogels. J. Mech. Behav. Biomed. Mater. 2013, 18:152-166.
12. Kuijpers A.J., Engbers G.H.M., Krijgsveld J., Zaat S.A.J., Dankert J., Feijen J. Cross-linking and characterization of gelatin matrices for biomedical applications. J. Biomater. Sci. Polym. Ed. 2000, 11(3):225-243.
13. Balakrishnam B., Mohanty M., Umaskankar P.R., Jayakrishnan A. Evaluation of an in situ forming hydrogel wound dressing based on oxidized alginate and gelatin. Biomaterials 2005, 26:6335-6342.
14. Boanini E., Rubini K., Panzovolta S., Bigi A. Chemico-physical characterization of gelatin films modified with oxidized alginate. Acta Biomater. 2010, 6:383-388.
15. Atiyeh B.S., Costagliola M., Hayek S.N., Dibo S.A. Effect of silver on burn wound infection control and healing: review of the literature. Burns 2007, 33:139-148.
16. Carter M.J., Tingley-Kelley K., Warriner R.A. Silver treatments and silver-impregnated dressings for the healing of leg wounds and ulcers: a systematic review and meta-analysis. J. Am. Acad. Dermatol. 2010, 63(4):668-679.
17. Watson N.F.S., Hodgkin W. Wound dressings. Surgery 2005, 23(2):52-55.
18. Ayensu I., Mitchell J.C., Boateng J.S. Effect of membrane dialysis on characteristics of lyophilized chitosan wafers for potential buccal delivery of proteins. Int. J. Biol. Macromol. 2012, 50:905-909.
19. Boateng J.S., Pawar H.V., Tetteh J. Polyox and carrageenan based composite film dressing containing anti-microbial and anti-inflammatory drugs for effective wound healing. Int. J. Pharm. 2013, 441(1-2):181-191.
20. Boateng J.S., Auffret A.D., Matthews K.H., Humphrey M.J., Stevens H.N.E., Eccleston G.M. Characterization of freeze-dried wafers and solvent evaporated films as potential drug delivery systems to mucosal surfaces. Int. J. Pharm. 2010, 389:24-31.
21. Dong Z., Wang Q., Du Y. Alginate/gelatin blend films and their properties for drug controlled release. J. Membr. Sci. 2006, 280:37-44.
22. Choi Y.S., Hong S.R., Lee Y.M., Song K.W., Park M.H., Nam Y.S. Study on gelatin-containing artificial skin: I. Preparation and characteristics of novel gelatin-alginate sponge. Biomaterials 1999, 20(5):409-417.
23. Devi N., Kakati D.K. Smart porous microparticles based on gelatin/sodium alginate polyelectrolyte complex. J. Food Eng. 2013, 117:193-204.
24. Li Y., Ji H., Cheng Q., Pan F., Jiang Z. Sodium alginate-gelatin polyelectrolyte complex membranes with both high water vapor permeance and high selectivity. J. Membr. Sci. 2011, 375(1-2):304-312.
25. Aziz Z., Abu S.F., Chong N.J. A systematic review of silver-containing dressings and topical silver agents (used with dressings) for burn wounds. Burns 2012, 38:307-318.
26. Liu G., Zhao X. Electroresponsive behavior of gelatin/alginate semi-interpenetrating polymer network membranes under direct-current electric field. J. Macromol. Sci. A: Pure Appl. Chem. 2006, 43:345-354.
27. Roy A., Bajpai J., Bajpai A.K. Development of calcium alginate-gelatin based microspheres for controlled release of endosulfan as a model pesticide. Indian J. Chem. Technol. 2009, 16:388-395.
28. Fajardo A.R., Lopes L.C., Caleare A.O., Britta E.A., Nakamura C.V., Rubira A.F., Muniz E.C. Silver sulfadiazine loaded chitosan/chondroitin sulfate films for a potential wound dressing application. Mater. Sci. Eng., C 2013, 33:588-595.
29. Singh B., Sharmab S., Dhimana A. Design of antibiotic containing hydrogel wound dressings: biomedical properties and histological study of wound healing. Int. J. Pharm. 2013, 457:82-91.
30. Salamat-Miller N., Chittchang M., Johnston T.P. The use of mucoadhesive polymers in buccal drug delivery. Adv. Drug Delivery Rev. 2005, 57:1666-1691.
31. Asane G.S., Nirmal S.A., Rasal K.B., Naik A.A., Mahadik M.S. Polymers for mucoadhesive drug delivery system: a current status. Drug Dev. Ind. Pharm. 2008, 34:1246-1266.
32. Roy S., Pal K., Anis A., Pramanik K., Prabhakar B. Polymers in mucoadhesive drug-delivery systems: a brief note. Des. Monomers Polym. 2009, 12:483-495.
33. Jiang L., Gao L., Wang X., Tang L., Ma J. The application of mucoadhesive polymers in nasal drug delivery. Drug Dev. Ind. Pharm. 2010, 36(3):323-336.
34. Howard S.C., Wlodkowski T.J., Rosenkranz H.S. Silver sulfadiazine: in vitro antibacterial activity. Antimicrob. Agents Chemother. 1973, 4(5):585-587.