Plasminogen activator inhibitor-1 regulates LPS induced inflammation in rat macrophages through autophagy activation

Scientific World Journal

Volumn 2014, Issue , 2014, Pages

  Wang, Zhong Hui ^a   Ren, Wei Ying ^a   Zhu, Lei ^a   Hu, Li Juan ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BECLIN 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; PLASMINOGEN ACTIVATOR INHIBITOR 1; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, RAT; LC3 PROTEIN, RAT; MICROTUBULE ASSOCIATED PROTEIN; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE OVEREXPRESSION; GENE SILENCING; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE; MACROPHAGE CULTURE; NONHUMAN; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; RAT; REGULATORY MECHANISM; RESPIRATORY TRACT INFLAMMATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUPERNATANT; WESTERN BLOTTING; AGONISTS; ANIMAL; CELL LINE; DRUG EFFECTS; GENETICS; INFLAMMATION; METABOLISM; PHYSIOLOGY;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELL LINE; INFLAMMATION; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MACROPHAGES; MICROTUBULE-ASSOCIATED PROTEINS; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PLASMINOGEN ACTIVATOR INHIBITOR 1; RATS; RNA, MESSENGER; TOLL-LIKE RECEPTOR 4; TOR SERINE-THREONINE KINASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84929055256     PISSN: 23566140     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1155/2014/189168     Document Type: Article

References (39)

1. L. B. Ware and M. A. Matthay, "The acute respiratory distress syndrome, " The New England Journal of Medicine, vol. 342, no. 18, pp. 1334-1349, 2000.
2. M. S. Herridge, A. M. Cheung, C. M. Tansey, et al., "Oneyear outcomes in survivors of the acute respiratory distress syndrome, "The New England Journal of Medicine, vol. 348, no. 8, pp. 683-693, 2003.
3. C. Brun-Buisson, C. Minelli, G. Bertolini, et al., "Epidemiology and outcome of acute lung injury in European intensive care units. Results from the ALIVE study, " Intensive Care Medicine, vol. 30, pp. 51-61, 2004.
4. J.-D. Vassalli, A.-P. Sappino, and D. Belin, "The plasminogen activator/plasmin system, " Journal of Clinical Investigation, vol. 88, no. 4, pp. 1067-1072, 1991.
5. R. Renckens, J. J. T. H. Roelofs, P. I. Bonta, et al., "Plasminogen activator inhibitor type 1 is protective during severe Gramnegative pneumonia, " Blood, vol. 109, no. 4, pp. 1593-1601, 2007.
6. A. Sapru, M. A. Q. Curley, S. Brady, M. A. Matthay, and H. Flori, "Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury, " Intensive Care Medicine, vol. 36, no. 1, pp. 157-163, 2010.
7. W. P. Fay, "Plasminogen activator inhibitor 1, fibrin, and the vascular response to injury, " Trends in Cardiovascular Medicine, vol. 14, no. 5, pp. 196-202, 2004.
8. H. A. Chapman Jr., O. L. Stone, and Z. Vavrin, "Degradation of fibrin and elastin by intact human alveolar macrophages in vitro. Characterization of a plasminogen activator and its role in matrix degradation, "The Journal of Clinical Investigation, vol. 73, no. 3, pp. 806-815, 1984.
9. H. A. Chapman Jr. and O. L. Stone, "A fibrinolytic inhibitor of human alveolar macrophages: induction with endotoxin, " The American Review of Respiratory Disease, vol. 132, no. 3, pp. 569-575, 1985.
10. H. A. Chapman, X. Yang, L. Z. Sailor, and D. J. Sugarbaker, "Developmental expression of plasminogen activator inhibitor type 1 by human alveolar macrophages. Possible role in lung injury, " Journal of Immunology, vol. 145, no. 10, pp. 3398-3405, 1990.
11. I. Vadász, R. E. Morty, A. Olschewski, et al., "Thrombin impairs alveolar fluid clearance by promoting endocytosis of Na+, K+-ATPase, " American Journal of Respiratory Cell and Molecular Biology, vol. 33, no. 4, pp. 343-354, 2005.
12. L. B. Ware, M. A. Matthay, P. E. Parsons, et al., "Pathogenetic and prognostic significance of altered coagulation and fibrinolysis in acute lung injury/acute respiratory distress syndrome, " Critical Care Medicine, vol. 35, no. 8, pp. 1821-1828, 2007.
13. J. Ma, Q. Sun, R. Mi, and H. Zhang, "Avian influenza A virus H5N1 causes autophagy-mediated cell death through suppression ofmTOR signaling, " Journal of Genetics andGenomics, vol. 38, no. 11, pp. 533-537, 2011.
14. D. J. Klionsky and S. D. Emr, "Autophagy as a regulated pathway of cellular degradation, " Science, vol. 290, no. 5497, pp. 1717-1721, 2000.
15. E. H. Baehrecke, "Autophagy: dual roles in life and death?" Nature ReviewsMolecular Cell Biology, vol. 6, no. 6, pp. 505-510, 2005.
16. L. Yu, F. Wan, S. Dutta, et al., "Autophagic programmed cell death by selective catalase degradation, " Proceedings of the National Academy of Sciences of the United States of America, vol. 103, no. 13, pp. 4952-4957, 2006.
17. H. W. Virgin and B. Levine, "Autophagy genes in immunity, " Nature Immunology, vol. 10, no. 5, pp. 461-470, 2009.
18. Y. Xu, C. Jagannath, X. Liu, A. Sharafkhaneh, K. E. Kolodziejska, and N. T. Eissa, "Toll-like receptor 4 is a sensor for autophagy associated with innate immunity, " Immunity, vol. 27, no. 1, pp. 135-144, 2007.
19. J. Huang, V. Canadien, G. Y. Lamet al., "Activation of antibacterial autophagy byNADPHoxidases, " Proceedings of theNational Academy of Sciences of the United States of America, vol. 106, no. 15, pp. 6226-6231, 2009.
20. P. W. M. Hermans and J. A. Hazelzet, "Plasminogen activator inhibitor type 1 gene polymorphism and sepsis, " Clinical Infectious Diseases, vol. 41, supplement 7, pp. S453-S458, 2005.
21. C. Dellas and D. J. Loskutoff, "Historical analysis of PAI-I from its discovery to its potential role in cell motility and disease, " Thrombosis & Haemostasis, vol. 93, no. 4, pp. 631-640, 2005.
22. I. Kucharewicz, K. Kowal, W. Buczko, and A. Bodzentałukaszyk, "The plasmin system in airway remodeling, " Thrombosis Research, vol. 112, no. 1-2, pp. 1-7, 2004.
23. H. R. Lijnen, "Pleiotropic functions of plasminogen activator inhibitor-1, " Journal of Thrombosis and Haemostasis, vol. 3, no. 1, pp. 35-45, 2005.
24. S. Shetty, J. Padijnayayveetil, T. Tucker, D. Stankowska, and S. Idell, "The fibrinolytic system and the regulation of lung epithelial cell proteolysis, signaling, and cellular viability, " The American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 295, no. 6, pp. L967-L975, 2008.
25. P. Prabhakaran, L. B. Ware, K. E. White, M. T. Cross, M. A. Matthay, and M. A. Olman, "Elevated levels of plasminogen activator inhibitor-1 in pulmonary edema fluid are associated with mortality in acute lung injury, " American Journal of Physiology-Lung Cellular andMolecular Physiology, vol. 285, no. 1, pp. L20-L28, 2003.
26. I. Tsangaris, A. Tsantes, S. Bonovas, et al., "The impact of the PAI-1 4G/5G polymorphism on the outcome of patients with ALI/ARDS, " Thrombosis Research, vol. 123, no. 6, pp. 832-836, 2009.
27. K. Yao, C. Sun, W. Xu, and R. Wu, "Lipopolysaccharide upregulates the expression of Toll-like receptor 4 in human vascular endothelial cells, " ChineseMedical Journal, vol. 115, no. 2, pp. 286-289, 2002.
28. F. Hua, W. Ren, and L. Zhu, "Plasminogen activator inhibitor type-1 deficiency exaggerates LPS-induced acute lung injury through enhancing Toll-like receptor 4 signaling pathway, " Blood Coagulation & Fibrinolysis, vol. 22, no. 6, pp. 480-486, 2011.
29. I. Kotani, A. Sato, H. Hayakawa, T. Urano, Y. Takada, and A. Takada, "Increased procoagulant and antifibrinolytic actvities in the lungs with idiopathic pulmonary fibrosis, " Thrombosis Research, vol. 77, no. 6, pp. 493-504, 1995.
30. B. Levine and G. Kroemer, "Autophagy in the pathogenesis of disease, " Cell, vol. 132, no. 1, pp. 27-42, 2008.
31. G. Cavallini, A. Donati, M. Taddei, and E. Bergamini, "Evidence for selective mitochondrial autophagy and failure in aging, " Autophagy, vol. 3, no. 1, pp. 26-27, 2007.
32. N. Mizushima, T. Yoshimori, and B. Levine, "Methods in mammalian autophagy research, " Cell, vol. 140, no. 3, pp. 313-326, 2010.
33. D. J. Klionsky, H. Abeliovich, P. Agostinis, et al., "Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes, " Autophagy, vol. 4, no. 2, pp. 151-175, 2008.
34. Q. Sun, W. Fan, and Q. Zhong, "Regulation of Beclin 1 in autophagy, " Autophagy, vol. 5, no. 5, pp. 713-716, 2009.
35. Y. Uchiyama, M. Shibata, M. Koike, K. Yoshimura, and M. Sasaki, "Autophagy-physiology and pathophysiology, " Histochemistry and Cell Biology, vol. 129, no. 4, pp. 407-420, 2008.
36. J. Harris, S. S. Master, S. A. de Haro, et al., "Th1-Th2 polarisation and autophagy in the control of intracellular mycobacteria by macrophages, " Veterinary Immunology and Immunopathology, vol. 128, no. 1-3, pp. 37-43, 2009.
37. N. Mizushima, "Autophagy: process and function, " Genes & Development, vol. 21, no. 22, pp. 2861-2873, 2007.
38. K. Inoki, M. N. Corradetti, and K. L. Guan, "Dysregulation of the TSC-mTOR pathway in human disease, " Nature Genetics, vol. 37, no. 1, pp. 19-24, 2005.
39. C. H. Eng, K. Yu, J. Lucas, E. White, and R. T. Abraham, "Ammonia derived from glutaminolysis is a diffusible regulator of autophagy, " Science Signaling, vol. 3, no. 119, p. ra31, 2010.