Plasminogen activator inhibitor type-1 deficiency exaggerates LPS-induced acute lung injury through enhancing Toll-like receptor 4 signaling pathway

Blood Coagulation and Fibrinolysis

Volumn 22, Issue 6, 2011, Pages 480-486

  Hua, Feng ^a,b   Ren, Weiying ^a   Zhu, Lei ^a  

^a FUDAN UNIVERSITY   (China)

^b HUZHOU CENTRAL HOSPITAL   (China)

Author keywords

acute lung injury; inflammation; lipopolysaccharide; plasminogen activator inhibitor 1; Toll like receptor 4

Indexed keywords

INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 3; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; STRESS ACTIVATED PROTEIN KINASE; SUPPRESSOR OF CYTOKINE SIGNALING 1; TOLL LIKE RECEPTOR 4;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; HISTOPATHOLOGY; LUNG FLUID; LUNG PARENCHYMA; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UPREGULATION; WESTERN BLOTTING;

ACUTE LUNG INJURY; ANIMALS; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; CYTOKINES; DOWN-REGULATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; INTUBATION, INTRATRACHEAL; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PLASMINOGEN ACTIVATOR INHIBITOR 1; SIGNAL TRANSDUCTION; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TOLL-LIKE RECEPTOR 4; UP-REGULATION;

EID: 80052098746     PISSN: 09575235     EISSN: 14735733     Source Type: Journal    
DOI: 10.1097/MBC.0b013e328346ef56     Document Type: Article

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