The Relationship between Cognitive Reserve and Functional Ability is Mediated by Executive Functioning in Older Adults

Clinical Neuropsychologist

Volumn 29, Issue 1, 2015, Pages 67-81

  Puente, Antonio Nicolas ^a,c   Lindbergh, Cutter A ^a   Miller, L Stephen ^a,b  

^a University of Georgia   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ADLs; Aging; Cognitive reserve; Executive functioning; Functional ability; Older adults

Indexed keywords

AGED; COGNITION; COGNITIVE RESERVE; DAILY LIFE ACTIVITY; EXECUTIVE FUNCTION; FEMALE; GERIATRIC ASSESSMENT; HUMAN; MALE; NEUROPSYCHOLOGICAL TEST; PHYSIOLOGY; PROCEDURES; PSYCHOMOTOR PERFORMANCE;

ACTIVITIES OF DAILY LIVING; AGED; COGNITION; COGNITIVE RESERVE; EXECUTIVE FUNCTION; FEMALE; GERIATRIC ASSESSMENT; HUMANS; MALE; NEUROPSYCHOLOGICAL TESTS; PSYCHOMOTOR PERFORMANCE;

EID: 84929026311     PISSN: 13854046     EISSN: 17444144     Source Type: Journal    
DOI: 10.1080/13854046.2015.1005676     Document Type: Article

References (82)

1. Alvarez, J. A., & Emory, E. (2006). Executive function and the frontal lobes: A meta-analytic review. Neuropsychology Review, 16, 17-42. doi:10.1007/s11065-006-9002-x
2. American Psychiatric Association (2004). Diagnostic and statistical manual of mental disorders text revision (4th ed.). Arlington, VA: American Psychiatric Publishing Inc.
3. Army Individual Test Battery. (1944). Manual of directions and scoring. Washington, DC: War Department, Adjutant General's Office.
4. Artero, S., Touchon, J., & Ritchie, K. (2001). Disability and mild cognitive impairment: A longitudinal population-based study. International Journal of Geriatric Psychiatry, 16, 1092-1097. doi:10.1002/gps.477
5. Avlund, K., Damsgaard, M. T., & Osler, M. (2004). Social position and functional decline among non-disabled old men and women. European Journal of Public Health, 14, 212-216.
6. Baker, D. W., Sudano, J. J., Albert, J. M., Borawski, E. A., & Dor, A. (2001). Lack of health insurance and decline in overall health in late middle age. The New England Journal of Medicine, 345, 1106-1112.
7. Ball, J. D., Hart, R. P., Stutts, M. L., Turf, E., & Barth, J. T. (2007). Comparative utility of Barona formulae, WTAR demographic algorithms, and WRAT-3 reading for estimating premorbid ability in a diverse research sample. The Clinical Neuropsychologist, 21, 422-433.
8. Barberger-Gateau, P., Fabrigoule, C., Rouch, I., Letenneur, L., & Dartigues, J. F. (1999). Neuropsychological correlates of self-reported performance in instrumental activities of daily living and prediction of dementia. The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences, 54, 293-303.
9. Baron, R. M., & Kenny, D. A. (1986). The Moderator-Mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. Journal of Personality and Social Psychology, 51, 1173-1182.
10. Basak, C., Boot, W. R., Voss, M. W., & Kramer, A. F. (2008). Can training in a real-time strategy video game attenuate cognitive decline in older adults? Psychology and Aging, 23, 765-777.
11. Bedard, M., Squire, L., Minthorn-Biggs, M. B., Molloy, D. W., Dubois, S., O'Donnell, M., & Lever, J. A. (2003). Validity of self-reports in dementia research. Clinical Gerontologist, 26, 155-163.
12. Bell-McGinty, S., Podell, K., Franzen, M., Baird, A. D., & Williams, M. J. (2002). Standard measures of executive function in predicting instrumental activities of daily living in older adults. International Journal of Geriatric Psychiatry, 17, 828-834. doi:10.1002/gps.646
13. Benton, A. L., & Hamsher, K. (1976). Multilingual aphasia examination. Iowa City, IA: University of Iowa.
14. Bherer, L., Kramer, A. F., Peterson, M. S., Colcombe, S., Erickson, K., & Becic, E. (2005). Training effects on dual-task performance: Are there age-related differences in plasticity of attentional control? Psychology and Aging, 20, 695-709.
15. Bickel, H., & Kurz, A. (2009). Education, occupation, and dementia: The Bavarian school sisters study. Dementia and Geriatric Cognitive Disorders, 27, 548-556. doi:10.1159/000227781
16. Borys, S. V., Spitz, H. H., & Dorans, B. A. (1982). Tower of Hanoi performance of retarded young adults and non-retarded children as a function of solution length and goal state. Journal of Experimental Child Psychology, 33, 87-110.
17. Burton, C. L., Strauss, E., Hultsch, D. F., & Hunter, M. A. (2006). Cognitive functioning and everyday problem solving in older adults. The Clinical Neuropsychologist, 20, 432-452. doi:10.1080/13854040590967063
18. Cahn-Weiner, D. A., Boyle, P. A., & Malloy, P. F. (2002). Tests of executive function predict instrumental activities of daily living in community-dwelling older individuals. Applied Neuropsychology, 9, 187-191. doi:10.1207/S15324826AN0903-8
19. Cahn-Weiner, D. A., Malloy, P. F., Boyle, P. F., Marran, M., & Salloway, S. (2000). Prediction of functional status from neuropsychological tests in community-dwelling elderly individuals. The Clinical Neuropsychologist, 14, 187-195. doi:10.1076/1385-4046(200005)14:2;1-Z; FT187
20. Carlson, M. C., Saczynski, J. S., Rebok, G. W., Seeman, T., Glass, T. A., McGill, S., ... Fried, L. P. (2008). Exploring the effects of an 'Everyday' activity program on executive function and memory in older adults: Experience corps. The Gerontologist, 48, 793-801.
21. Cohen, J. (1988). Statistical power analysis for the behavioral sciences. Hillsdale, NJ: Erlbaum.
22. Cohen, J., Cohen, P., West, S., & Aiken, L. (2002). Applied multiple regression/correlation analysis behavioral sciences (3rd ed.). New York, NY: Taylor & Francis.
23. Cohen, R. A., Bloom, B., Simpson, G, & Parsons, P.E. (1997). Access to health care. Part 3: Older adults. National Center for Health Statistics. (DHHS publication; no. (PHS) 97-1526). Washington, DC: U.S. Government Printing Office.
24. Colcombe, S., & Kramer, A. (2003). Fitness effects on the cognitive function of older adults: A meta-analytic study. Psychological Science, 14, 125-130.
25. Dahlin, E., Nyberg, L., Bäckman, L., & Neely, A. S. (2008). Plasticity of executive functioning in young and older adults: Immediate training gains, transfer and long-term maintenance. Psychology and Aging, 23, 720-730.
26. Delis, D. C., Kaplan, E., & Kramer, J. H. (2001). Delis-Kaplan executive function system technical manual. San Antonio, TX: The Psychological Corporation.
27. Dubowitz, T., Heron, M., Bird, C. E., Lurie, N., Finch, B. K., Basurto-Davila, R., ... Escarce, J. J. (2008). Neighborhood socioeconomic status and fruit and vegetable intake among White, Blacks, and Mexican-Americans in the United States. The American Journal of Clinical Nutrition, 87, 1883-1891.
28. Fratiglioni, L., Paillard-Borg, S., & Winblad, B. (2004). An active and socially integrated lifestyle in late life might protect against dementia. The Lancet Neurology, 3, 343-353.
29. Gill, T. M., Williams, C. S., Richardson, E. D., & Tinetti, M. E. (1996). Impairments in physical performance and cognitive status as predisposing factors for functional dependence among non-disabled older persons. Journal of Gerontology, 51A, M283-M288.
30. Gross, A. L., Rebok, G. W., Unverzagt, F. W., Willis, S. L., & Brandt, J. (2012). Word list memory predicts everyday function and problem-solving in the elderly: Results from the ACTIVE Cognitive Intervention Trial. Neuropsychological, Development, and Cognition Section B Aging, Neuropsychology and Cognition, 18, 129-146. doi:10.1080/13825585.2010.516814.Word
31. Hoeymans, N., Wouters, E. R., Feskens, E. J., van den Bos, G. A., & Kromhout, D. (1997). Reproducibility of performance-based and self-reported measures of functional status. The Journals of Gerontology Series A, Biological Sciences and Medical Sciences, 52, 363-368.
32. Hughes, J. P., McDowell, M. A., & Brody, D. J. (2008). Leisure-time physical activity among US adults 60 or more years of age: Results from NHANES 1999-2004. Journal of Physical Activity and Health, 5, 347-358.
33. Hung, W. W., Ross, J. S., Boockvar, K. S., & Siu, A. L. (2011). Recent trends in chronic disease, impairment and disability among older adults in the United States. BMC Geriatrics, 11(47), 1-12.
34. Janssen, I., Heymsfield, S. B., & Ross, R. (2002). Low relative skeletal muscle mass is associated with functional impairment and physical disability. Journal of American Geriatric Society, 50, 889-896.
35. Jefferson, A., Paul, R. H., Ozonoff, A., & Cohen, R. A. (2006). Evaluating elements of executive functioning as predictors of instrumental activities of daily living (IADLs). Archives of Clinical Neuropsychology, 21, 311-320.
36. Kinsella, K. & Wan, H. (2009). U.S. Census bureau: international International population reports, An Aging World: 2008. Washington, DC: U.S. Government Printing Office.
37. Laukkanen, P., Kauppinen, M., Era, P., & Heikkinen, E. (1993). Factors related to coping with physical and instrumental activities of daily living among people born in 1904-1923. International Journal of Geriatric Psychiatry, 8, 287-296.
38. Lee, S., Buring, J., Cook, N., & Grodstein, F. (2007). The relation of education and income to cognitive function among professional women. Neuroepidemiology, 26, 93-101.
39. Lee, Y. (2000). The predictive value of self assessed general, physical, and mental health on functional decline and mortality in older adults. Journal of Epidemiology and Community Health, 54, 123-129.
40. Lewis, M. S., & Miller, L. S. (2007). Executive control functioning and functional ability in older adults. The Clinical Neuropsychologist, 21, 274-285. doi:10.1080/13854040500519752
41. Lezak, M., Howieson, D. B., Bigler, E. D., & Tranel, D. (2012). Neuropsychological Assessment (5th ed.). New York, NY: Oxford University Press.
42. Li, C. Y., Wu, S. C., & Wen, S. W. (2000). Longest held occupation in a lifetime and risk of disability in activities of daily living. Occupational and Environmental Medicine, 57, 550-554.
43. Loewenstein, D. A., & Bates, B. C. (1989). The direct assessment of functional status (DAFS): Manual for administration and scoring. Unpublished manuscript.
44. Mitchell, M., & Miller, L. S. (2008a). Prediction of functional status in older adults: The ecological validity of four Delis-Kaplan Executive Function System tests. Journal of Clinical and Experimental Neuropsychology, 30, 683-690. doi:10.1080/13803390701679893
45. Mitchell, M., & Miller, L. S. (2008b). Executive functioning and observed versus self-reported measures of functional ability. The Clinical Neuropsychologist, 22, 471-479. doi:10.1080/13854040701336436
46. Mitchell, M. B., Shaughnessy, L. W., Shirk, S. D., Yang, F. M., & Atri, A. (2012). Neuropsychological test performance and cognitive reserve in healthy aging and the Alzheimer's disease spectrum: A theoretically driven factor analysis. Journal of the International Neuropsychological Society, 18, 1071-1080.
47. Myers, A. M., Holliday, P. J., Harvey, K. A., & Hutchinson, K. S. (1993). Functional performance measures: Are they superior to self-assessments? Journal of Gerontology, 48, M196-M206.
48. Paterson, D. H., & Warburton, D. E. (2010). Physical activity and functional limitations in older adults: A systematic review related to Canada's Physical Activity Guidelines. The International Journal of Behavioral Nutrition and Physical Activity, 7, 1-22. doi:10.1186/1479-5868-7-38
49. Parker, M. G., Thorslund, M., & Lundberg, O. (1994). Physical function and social class among Swedish oldest old. Journal of Gerontology: Social Sciences, 49, S196-S201.
50. Pereira, F. S., Yassuda, M. S., Oliveira, A. M., & Forlenza, O. V. (2008). Executive dysfunction correlates with impaired functional status in older adults with varying degrees of cognitive impairment. International Psychogeriatrics, 20, 1104-1115. doi:10.1017/S1041610208007631
51. Petrella, J. K., Miller, L. S., & Cress, M. E. (2004). Leg extensor power, cognition, and functional performance in independent and marginally dependent older adults. Age and Ageing, 33, 342-348. doi:10.1093/ageing/afh055
52. Plehn, K., Marcopulos, B. A., & McLain, C. A. (2004). The relationship between neuropsychological test performance, social functioning, and instrumental activities of daily living in a sample of rural older adults. The Clinical Neuropsychologist, 18, 101-113. doi:10.1080/13854040490507190
53. Preacher, K. J., & Hayes, A. (2004). SPSS and SAS procedures for estimating indirect effects in simple mediation models. Behavioral Research Methods, Instruments, & Computers, 36, 717-731.
54. Reed, B. R., Mungas, D., Farias, S. T., Harvey, D., Beckett, L., Widaman, K., ... DeCarli, C. (2010).0 Measuring cognitive reserve based on the decomposition of episodic memory variance. Brain, 133, 2196-2209.
55. Roldán-Tapia, L., Garica, J., Cánovas, R., & León, I. (2012). Cognitive reserve, age and their relation to attentional and executive functions. Applied Neuropsychology, 19, 2-8.
56. Roos, P. A., & Treiman, D. J. (1980). DOT scales for the 1970 Census classification. In A. R. Miller, D. J. Treiman, P. S. Cain, & P. A. Roos (Eds.), Work, jobs, and occupations: A critical review of occupational titles. Washington, DC: National Academy Press.
57. Royall, D. R., Chiodo, L. K., & Polk, M. J. (2000). Correlates of disability among elderly retirees with 'subclinical' cognitive impairment. The Journals of Gerontology Series A, Biological Sciences and Medical Sciences, 55, M541-M546.
58. Ruff, R. M. (1988). Ruff Figural Fluency Test, professional manual. Odessa, FL: Psychological Assessment Resources.
59. Scarmeas, N., & Stern, Y. (2003). Cognitive reserve and lifestyle. Journal of Clinical and Experimental Neuropsychology, 25, 625-633.
60. Scarmeas, N., Stern, Y., Tang, M.-X., Mayeux, R., & Luchsinger, J. A. (2006). Mediterranean diet and risk for Alzheimer's disease. Annals of Neurology, 59, 912-921.
61. Schmitter-Edgecombe, M., Woo, E., & Greeley, D. R. (2009). Characterizing multiple memory deficits and their relation to everyday functioning in individuals with mild cognitive impairment. Neuropsychology, 23, 168-177. doi:10.1037/a0014186
62. Schofield, P. (1999). Alzheimer's disease and brain reserve. Australasian Journal on Ageing, 18, 10-14.
63. Shallice, T. (1982). Specific impairments of planning. Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 298, 199-209.
64. Sherman, S. E., & Reuben, D. (1998). Measures of functional status in community-dwelling elders. Journal of General Internal Medicine, 13, 817-823.
65. Siedlecki, K. L., Stern, Y., Reuben, A., Sacco, R. L., Elkind, M. S. V., & Wright, C. B. (2009). Construct validity of cognitive reserve in a multi-ethnic cohort: The northern Manhattan study. Journal of the International Neuropsychological Society, 15, 558-569.
66. Sobel, M. E. (1982). Asymptotic intervals for indirect effects in structural equations models. In S. Leinhart (Ed.), Sociological methodology (pp. 290-312). San Francisco, CA: Jossey-Bass.
67. Starr, J. M., & Lonie, J. (2008). Estimated pre-morbid IQ effects on cognitive and functional outcomes in Alzheimer disease: A longitudinal study in a treated cohort. BMC Psychiatry, 8, 1-8. doi:10.1186/1471-244X-8-27
68. Steiger, J. H. (1980). Tests for comparing elements of a correlation matrix. Psychological Bulletin, 87, 245-252.
69. Stern, Y. (2002). What is cognitive reserve? Theory and research application of the reserve concept. Journal of the International Neuropsychological Society, 8, 448-460.
70. Stern, Y. (2009). Cognitive reserve. Neuropsychologia, 47, 2015-2028. doi:10.1016/j.neuropsychologia.2009.03.004.Cognitive
71. Stuss, D. T., & Benson, D. F. (1986). The frontal lobes. New York, NY: Raven Press.
72. Stuss, D. T., & Levine, B. (2002). Adult clinical neuropsychology: Lessons from studies of the frontal lobes. Annual Review of Psychology, 53, 401-433. doi:10.1146/annurev.psych.53.100901.135220
73. U.S. Department of Labor. (1977). Dictionary of occupational titles (4th ed.). Washington, DC: U.S. Government Printing Office.
74. Van der Elst, W., Van Boxtel, M. P. J., Van Breukelen, G. J. P., & Jolles, J. (2008). A large-scale cross-sectional and longitudinal study into the ecological validity of neuropsychological test measures in neurologically intact people. Archives of Clinical Neuropsychology, 23, 787-800. doi:10.1016/j.acn.2008.09.002
75. Wechsler, D. (2001). Wechsler test of adult reading. San Antonio, TX: The Psychological Corporation.
76. West, C. G., Gildengorin, G., Haegerstrom-Portnoy, G., Schneck, M. E., Lott, L., & Brabyn, J. A. (2002). Is vision function related to physical functional ability in older adults? Journal of the American Geriatrics Society, 50, 136-145.
77. Willis, S. L., Tennstedt, S. L., Marsiske, M., Ball, K., Elias, J., Koepke, K. M., ... Wright, E. (2006). Long-term effects of cognitive training on everyday functional outcomes in older adults. The Journal of the American Medical Association, 296, 2805-2814.
78. World Health Organization. (1992). The ICD-10 classification of mental and behavioural disorders: Clinical descriptions and diagnostic guidelines. Geneva: Author.
79. Yesavage, J. A., Brink, T. L., Rose, T. L., Lum, O., Huang, V., Adey, M., & Leirer, V. O. (1983). Development and validation of a geriatric depression screening scale: A preliminary report. Journal of Psychiatric Research, 17, 37-49. doi:10.1016/0022-3956(82)90033-4
80. Zahodne, L. B., Manly, J. J., Brickman, A. M., Siedlecki, K. L., Decarli, C., & Stern, Y. (2013). Quantifying cognitive reserve in older adults by decomposing episodic memory variance: Replication and extension. Journal of the International Neuropsychological Society, 19, 854-862. doi:10.1017/S1355617713000738
81. Zanetti, O., Geroldi, C., Frisoni, G. B., Bianchetti, A., & Trabucchi, M. (1999). Contrasting results between caregiver's report and direct assessment of activities of daily living in patients affected by mild and very mild dementia: The contribution of the caregiver's personal characteristics. Journal of the American Geriatrics Society, 47, 196-202.
82. Zunzunegui, M. V., Nunez, O., Durban, M., Garicia de Yébene, M. J., & Otero, Á. (2006). Decreasing prevalence of disability in activities of daily living, functional limitations and poor self-rated health: A 6-year follow-up study in Spain. Aging Clinical and Experimental Research, 18, 352-358.