메뉴 건너뛰기




Volumn 31, Issue 5, 2015, Pages 656-664

EQTL epistasis: Detecting epistatic effects and inferring hierarchical relationships of genes in biological pathways

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MODEL; BRAIN; COMPUTER SIMULATION; EPISTASIS; GENE; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HUMAN; PHYSIOLOGY; QUANTITATIVE TRAIT LOCUS; SCHIZOPHRENIA; SIGNAL TRANSDUCTION;

EID: 84928994263     PISSN: 13674803     EISSN: 14602059     Source Type: Journal    
DOI: 10.1093/bioinformatics/btu727     Document Type: Article
Times cited : (9)

References (20)
  • 1
    • 41949129310 scopus 로고    scopus 로고
    • From classical genetics to quantitative genetics to systems biology: Modeling epistasis
    • Aylor, D.L. and Zeng, Z.-B. (2008) From classical genetics to quantitative genetics to systems biology: modeling epistasis. PLoS Genet., 4, e1000029.
    • (2008) PLoS Genet. , vol.4 , pp. e1000029
    • Aylor, D.L.1    Zeng, Z.-B.2
  • 3
    • 3442894519 scopus 로고    scopus 로고
    • Epistasis: Too often neglected in complex trait studies?
    • Carlborg, O. and Haley, C.S. (2004) Epistasis: too often neglected in complex trait studies? Nat. Rev. Genet., 5, 618-625.
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 618-625
    • Carlborg, O.1    Haley, C.S.2
  • 4
    • 33747193538 scopus 로고    scopus 로고
    • Schizophrenia susceptibility genes converge on interlinked pathways related to glutamatergic transmission and long-term potentiation, oxidative stress and oligodendrocyte viability
    • Carter, C. (2006) Schizophrenia susceptibility genes converge on interlinked pathways related to glutamatergic transmission and long-term potentiation, oxidative stress and oligodendrocyte viability. Schizophr. Res., 86, 1-14.
    • (2006) Schizophr. Res. , vol.86 , pp. 1-14
    • Carter, C.1
  • 5
    • 0036797562 scopus 로고    scopus 로고
    • Epistasis: What it means, what it doesn't mean, and statistical methods to detect it in humans
    • Cordell, H.J. (2002) Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans. Human Mol. Genet., 11, 2463-2468.
    • (2002) Human Mol. Genet. , vol.11 , pp. 2463-2468
    • Cordell, H.J.1
  • 6
    • 67349166946 scopus 로고    scopus 로고
    • Detecting gene-gene interactions that underlie human diseases
    • Cordell, H.J. (2009) Detecting gene-gene interactions that underlie human diseases. Nat. Rev. Genet., 10, 392-404.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 392-404
    • Cordell, H.J.1
  • 7
    • 77952557918 scopus 로고    scopus 로고
    • Missing heritability and strategies for finding the underlying causes of complex disease
    • Eichler, E.E. et al. (2010) Missing heritability and strategies for finding the underlying causes of complex disease. Nat. Rev. Genet., 11, 446-450.
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 446-450
    • Eichler, E.E.1
  • 8
    • 84971185409 scopus 로고
    • The correlations between relatives on the supposition of Mendelian inheritance
    • Fisher, R. (1918) The correlations between relatives on the supposition of Mendelian inheritance. Trans. R. Soc. Edinb., 52, 399-433.
    • (1918) Trans. R. Soc. Edinb. , vol.52 , pp. 399-433
    • Fisher, R.1
  • 9
    • 84883539540 scopus 로고    scopus 로고
    • EQTL epistasis-challenges and computational approaches
    • Huang, Y. et al. (2013) eQTL epistasis-challenges and computational approaches. Front. Genet., 4, 51.
    • (2013) Front. Genet. , vol.4 , pp. 51
    • Huang, Y.1
  • 10
    • 84863505275 scopus 로고    scopus 로고
    • Leveraging input and output structures for joint mapping of epistatic and marginal eQTLs
    • Lee, S. and Xing, E.P. (2012) Leveraging input and output structures for joint mapping of epistatic and marginal eQTLs. Bioinformatics, 28, i137-i146.
    • (2012) Bioinformatics , vol.28 , pp. i137-i146
    • Lee, S.1    Xing, E.P.2
  • 11
    • 77955654595 scopus 로고    scopus 로고
    • Whole-genome association mapping of gene expression in the human prefrontal cortex
    • Liu, C. et al. (2010) Whole-genome association mapping of gene expression in the human prefrontal cortex. Mol. Psychiatry, 15, 779-784.
    • (2010) Mol. Psychiatry , vol.15 , pp. 779-784
    • Liu, C.1
  • 12
    • 84890562372 scopus 로고    scopus 로고
    • Epistasis and quantitative traits: Using model organisms to study gene-gene interactions
    • Mackay, T.F.C. (2014) Epistasis and quantitative traits: using model organisms to study gene-gene interactions. Nat. Rev. Genet., 15, 22-33.
    • (2014) Nat. Rev. Genet. , vol.15 , pp. 22-33
    • Mackay, T.F.C.1
  • 13
    • 16844366786 scopus 로고    scopus 로고
    • Genome-wide strategies for detecting multiple loci that influence complex diseases
    • Marchini, J. et al. (2005) Genome-wide strategies for detecting multiple loci that influence complex diseases. Nat. Genet., 37, 413-417.
    • (2005) Nat. Genet. , vol.37 , pp. 413-417
    • Marchini, J.1
  • 14
    • 84866081004 scopus 로고    scopus 로고
    • Epistasis network centrality analysis yields pathway replication across two GWAS cohorts for bipolar disorder
    • Pandey, A. et al. (2012) Epistasis network centrality analysis yields pathway replication across two GWAS cohorts for bipolar disorder. Transl. Psychiatry, 2, e154.
    • (2012) Transl. Psychiatry , vol.2 , pp. e154
    • Pandey, A.1
  • 15
    • 79958122719 scopus 로고    scopus 로고
    • Quantitative epistasis analysis and pathway inference from genetic interaction data
    • Phenix, H. et al. (2011) Quantitative epistasis analysis and pathway inference from genetic interaction data. PLoS Comput. Biol., 7, e1002048.
    • (2011) PLoS Comput. Biol. , vol.7 , pp. e1002048
    • Phenix, H.1
  • 16
    • 54149088214 scopus 로고    scopus 로고
    • Epistasis-the essential role of gene interactions in the structure and evolution of genetic systems
    • Phillips, P.C. (2008) Epistasis-the essential role of gene interactions in the structure and evolution of genetic systems. Nat. Rev. Genet., 9, 855-867.
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 855-867
    • Phillips, P.C.1
  • 17
    • 77953893931 scopus 로고    scopus 로고
    • Fastepistasis: A high performance computing solution for quantitative trait epistasis
    • Schupbach, T. et al. (2010) Fastepistasis: a high performance computing solution for quantitative trait epistasis. Bioinformatics, 26, 1468-1469.
    • (2010) Bioinformatics , vol.26 , pp. 1468-1469
    • Schupbach, T.1
  • 18
    • 75649111609 scopus 로고    scopus 로고
    • Empirical tests for compositional epistasis
    • VanderWeele, T.J. (2010) Empirical tests for compositional epistasis. Nat. Rev. Genet., 11, 166.
    • (2010) Nat. Rev. Genet. , vol.11 , pp. 166
    • Vanderweele, T.J.1
  • 19
    • 84873967707 scopus 로고    scopus 로고
    • The complete compositional epistasis detection in genome-wide association studies
    • Wan, X. et al. (2013) The complete compositional epistasis detection in genome-wide association studies. BMC Genet., 14, 7.
    • (2013) BMC Genet. , vol.14 , pp. 7
    • Wan, X.1
  • 20
    • 0036214980 scopus 로고    scopus 로고
    • Bone morphogenetic proteins bmp-6 and bmp-7 have differential effects on survival and neurite outgrowth of cerebellar granule cell neurons
    • Yabe, T. et al. (2002) Bone morphogenetic proteins bmp-6 and bmp-7 have differential effects on survival and neurite outgrowth of cerebellar granule cell neurons. J. Neurosci. Res., 68, 161-168.
    • (2002) J. Neurosci. Res. , vol.68 , pp. 161-168
    • Yabe, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.