Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation

European Journal of Cancer

Volumn 51, Issue 8, 2015, Pages 969-976

  Huang, Dong Sheng ^a,b   Wang, Zhaohui ^c   He, Xu Jun ^b   Diplas, Bill H ^c   Yang, Rui ^c   Killela, Patrick J ^c   Meng, Qun ^a   Ye, Zai Yuan ^a,b   Wang, Wei ^a   Jiang, Xiao Ting ^b   Xu, Li ^a   He, Xiang Lei ^a   Zhao, Zhong Sheng ^a   Xu, Wen Juan ^a   Wang, Hui Ju ^b   Ma, Ying Yu ^b   Xia, Ying Jie ^b   Li, Li ^b   Zhang, Ru Xuan ^b   Jin, Tao ^a   Zhao, Zhong Kuo ^a   Xu, Ji ^a   Yu, Sheng ^b   Wu, Fang ^b   Liang, Junbo ^d   Wang, Sizhen ^e   Jiao, Yuchen ^f   Yan, Hai ^c   Tao, Hou Quan ^a,b   more..

^a ZHEJIANG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^b Key Laboratory of Gastroenterology of Zhejiang Province   (China)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^e Beijing NDTech Co Ltd   (China)

^f CANCER HOSPITAL   (China)

Author keywords

China; Genetics; Glioma; Neoplasms; Promoter regions; Telomerase

Indexed keywords

TELOMERASE REVERSE TRANSCRIPTASE; TELOMERASE; TERT PROTEIN, HUMAN;

ARTICLE; BILE DUCT CARCINOMA; CHINESE; ENZYME ACTIVATION; GALLBLADDER CARCINOMA; GASTRIC SCHWANNOMA; GASTROINTESTINAL LEIOMYOMA; GASTROINTESTINAL STROMAL TUMOR; GENE MUTATION; GLIOBLASTOMA; HUMAN; HUMAN TISSUE; LEIOMYOMA; LIVER CELL CARCINOMA; LUCIFERASE ASSAY; MAJOR CLINICAL STUDY; MEDULLOBLASTOMA; MULTIPLE CANCER; NEURILEMOMA; OLIGODENDROGLIOMA; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TELOMERIC REPEAT AMPLIFICATION PROTOCOL; THYMIC EPITHELIAL TUMOR; THYMOMA; TRANSITIONAL CELL CARCINOMA; ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETICS; METABOLISM; MUTATION; NEOPLASMS; NUCLEOTIDE SEQUENCE; PATHOLOGY; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICS AND NUMERICAL DATA; TUMOR CELL CULTURE; UPREGULATION;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; BASE SEQUENCE; DNA MUTATIONAL ANALYSIS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; HUMANS; MUTATION; NEOPLASMS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; TELOMERASE; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 84928953693     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2015.03.010     Document Type: Article

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