Acetylation of human mitochondrial citrate carrier modulates mitochondrial citrate/malate exchange activity to sustain NADPH production during macrophage activation

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1847, Issue 8, 2015, Pages 729-738

  Palmieri, Erika M ^a   Spera, Iolanda ^a   Menga, Alessio ^a   Infantino, Vittoria ^c   Porcelli, Vito ^a   Iacobazzi, Vito ^a,b   Pierri, Ciro L ^a   Hooper, Douglas C ^d   Palmieri, Ferdinando ^a   Castegna, Alessandra ^a  

^a UNIVERSITY OF BARI   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF BASILICATA   (Italy)

^d THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Acetylation; Citrate; Inflammation; Macrophage; Mitochondrial citrate carrier; Post translational modification

Indexed keywords

CITRIC ACID; GLUCOSE; ISOCITRATE DEHYDROGENASE; MALATE DEHYDROGENASE (DECARBOXYLATING); MALIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; CARRIER PROTEIN; CITRATE-BINDING TRANSPORT PROTEIN; GAMMA INTERFERON; MALIC ACID DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SIRT3 PROTEIN, HUMAN; SIRTUIN 3; TUMOR NECROSIS FACTOR ALPHA;

ACETYLATION; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MACROPHAGE; MACROPHAGE ACTIVATION; MITOCHONDRION; PENTOSE PHOSPHATE CYCLE; PRIORITY JOURNAL; CELL CULTURE; DRUG EFFECTS; IMMUNOPRECIPITATION; METABOLISM; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL; U937 CELL LINE; WESTERN BLOTTING;

ACETYLATION; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CARRIER PROTEINS; CELLS, CULTURED; CITRIC ACID; CYTOSOL; GLUCOSE; HUMANS; IMMUNOPRECIPITATION; INTERFERON-GAMMA; MACROPHAGE ACTIVATION; MALATES; MITOCHONDRIA; NADP; SIRTUIN 3; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS;

EID: 84928914095     PISSN: 00052728     EISSN: 18792650     Source Type: Journal    
DOI: 10.1016/j.bbabio.2015.04.009     Document Type: Article

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