Single administration of ultra-low-dose lipopolysaccharide in rat early pregnancy induces TLR4 activation in the placenta contributing to preeclampsia

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Xue, Pingping ^a   Zheng, Mingming ^b   Gong, Ping ^c   Lin, Caimei ^a   Zhou, Jianjun ^c   Li, Yujing ^d   Shen, Li ^a   Diao, Zhenyu ^b   Yan, Guijun ^b   Sun, Haixiang ^b   Hu, Yali ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

^c NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^d MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN; SODIUM CHLORIDE; SYNAPTOTAGMIN I; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; RELA PROTEIN, RAT; TLR4 PROTEIN, RAT;

ADVERSE OUTCOME; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; EMBRYO; FEMALE; FETOPLACENTAL UNIT; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN TISSUE; HYPERTENSION; IMMUNE RESPONSE; INTRAUTERINE GROWTH RETARDATION; KIDNEY PARENCHYMA; NIDATION; NONHUMAN; PLACENTA; PREECLAMPSIA; PREGNANCY OUTCOME; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; PROTEINURIA; RAT; RAT MODEL; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SYSTOLIC BLOOD PRESSURE; TISSUE SPECIFICITY; TROPHOBLAST; AGONISTS; ANIMAL; BLOOD PRESSURE; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; FETUS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INTRAVENOUS DRUG ADMINISTRATION; PATHOPHYSIOLOGY; PREGNANCY; REPRODUCTION; SPRAGUE DAWLEY RAT; VASCULARIZATION;

RATTUS;

ANIMALS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; EMBRYO IMPLANTATION; FEMALE; FETAL GROWTH RETARDATION; FETUS; GENE EXPRESSION REGULATION; HUMANS; INJECTIONS, INTRAVENOUS; LIPOPOLYSACCHARIDES; PLACENTA; PLACENTATION; PRE-ECLAMPSIA; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA;

EID: 84928911466     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0124001     Document Type: Article

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