Decarboxylative Alkynyl Termination of Palladium-Catalyzed Catellani Reaction: A Facile Synthesis of α-Alkynyl Anilines via Ortho C - H Amination and Alkynylation

Organic Letters

Volumn 17, Issue 9, 2015, Pages 2222-2225

  Sun, Fenggang ^a   Gu, Zhenhua ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYNE; ANILINE DERIVATIVE; CARBOXYLIC ACID; PALLADIUM;

AMINATION; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; SYNTHESIS;

ALKYNES; AMINATION; ANILINE COMPOUNDS; CARBOXYLIC ACIDS; CATALYSIS; MOLECULAR STRUCTURE; PALLADIUM;

EID: 84928910865     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/acs.orglett.5b00830     Document Type: Article

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44. Byproduct 5v was isolated in 83% yield.
45. According to Catellani's results, only very low conversion was achieved (18% conversion with butylacetylene) even with 72 h gradual addition; see ref 6.