Polycyclic aromatic hydrocarbons reciprocally regulate IL-22 and IL-17 cytokines in peripheral blood mononuclear cells from both healthy and asthmatic subjects

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Plé, Coline ^a,b,c,d   Fan, Ying ^a,b,c,d   Yahia, Saliha Ait ^a,b,c,d   Vorng, Han ^a,b,c,d   Everaere, Laetitia ^a,b,c,d   Chenivesse, Cécile ^g   Balsamelli, Joanne ^a,b,c,d   Azzaoui, Imane ^a,b,c,d   De Nadai, Patricia ^a,b,c,d   Wallaert, Benoit ^a,b,c,d,e   Lazennec, Gwendal ^f   Tsicopoulos, Anne ^a,b,c,d,e  

^a INSERM   (France)

^b INSTITUT PASTEUR DE LILLE   (France)

^c INSERM U1019   (France)

^d UNIV LILLE   (France)

^e LILLE UNIVERSITY HOSPITAL   (France)

^f CNRS SysDiag UMR3145 Cap delta   (France)

^g PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE; CYTOCHROME P450 1A1; INTERLEUKIN 17; INTERLEUKIN 22; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NOTCH RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; POLYCYCLIC AROMATIC HYDROCARBON; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RETINOID RELATED ORPHAN RECEPTOR GAMMA; STRESS ACTIVATED PROTEIN KINASE; AROMATIC HYDROCARBON RECEPTOR; CYP1A1 PROTEIN, HUMAN; EXHAUST GAS; IL17A PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; RORA PROTEIN, HUMAN; RORC PROTEIN, HUMAN;

ALLERGIC ASTHMA; ARTICLE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYP1A1 GENE; CYTOKINE PRODUCTION; DISEASE EXACERBATION; DOWN REGULATION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; REGULATORY MECHANISM; UPREGULATION; ADULT; ANALYSIS; ASTHMA; CELL CULTURE; CHEMISTRY; CYTOLOGY; EXHAUST GAS; FEMALE; GENETICS; MALE; METABOLISM; MIDDLE AGED; MONONUCLEAR CELL; TH17 CELL;

ADULT; ASTHMA; BENZO(A)PYRENE; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CYTOCHROME P-450 CYP1A1; DOWN-REGULATION; FEMALE; HUMANS; INTERLEUKIN-17; INTERLEUKINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 1; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; PHOSPHATIDYLINOSITOL 3-KINASES; POLYCYCLIC AROMATIC HYDROCARBONS; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; TH17 CELLS; UP-REGULATION; VEHICLE EMISSIONS;

EID: 84928898514     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0122372     Document Type: Article

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