Acidified bile acids increase hTERT expression via c-myc activation in human gastric cancer cells

Oncology Reports

Volumn 33, Issue 6, 2015, Pages 3038-3044

  Wang, Xiaolong ^a   Zhou, Peihua ^a   Sun, Xuejun ^a   Zheng, Jianbao ^a   Wei, Guangbing ^a   Zhang, Li ^a   Wang, Hui ^b   Yao, Jianfeng ^b   Lu, Shaoying ^a   Jia, Pengbo ^c  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b SHAANXI PROVINCIAL PEOPLE S HOSPITAL   (China)

^c The First People's Hospital of Xianyang City   (China)

Author keywords

Acidified bile acids; C myc activation; Gastric cancer; HTERT; Telomerase activation

Indexed keywords

5 [4 ETHYLBENZYLIDINE] 2 THIOXOTHIAZOLIDIN 4 ONE; CHENODEOXYCHOLIC ACID; DEOXYCHOLIC ACID; MESSENGER RNA; MYC PROTEIN; PROTEIN INHIBITOR; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG; 5-(4-ETHYLBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE; BILE ACID; TERT PROTEIN, HUMAN; THIAZOLE DERIVATIVE;

ACIDIFICATION; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; GASTRIC CANCER CELL LINE; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE INDUCTION; HTERT GENE; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; ONCOGENE C MYC; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; STOMACH CANCER; TRANSCRIPTION INITIATION; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DRUG EFFECTS; GENETICS; METABOLISM; STOMACH NEOPLASMS; TUMOR CELL LINE;

BILE ACIDS AND SALTS; CELL LINE, TUMOR; CHENODEOXYCHOLIC ACID; DEOXYCHOLIC ACID; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-MYC; RNA, MESSENGER; STOMACH NEOPLASMS; TELOMERASE; THIAZOLES; TRANSCRIPTIONAL ACTIVATION;

EID: 84928886203     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2015.3908     Document Type: Article

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