Insight into the evolution and origin of leprosy bacilli from the genome sequence of Mycobacterium lepromatosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 14, 2015, Pages 4459-4464

  Singh, Pushpendra ^a,f   Benjak, Andrej ^a   Schuenemann, Verena J ^b   Herbig, Alexander ^b   Avanzi, Charlotte ^a   Busso, Philippe ^a   Nieselt, Kay ^b   Krause, Johannes ^b,c,d   Vera Cabrera, Lucio ^e   Cole, Stewart T ^a  

^a EPFL   (Switzerland)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c Senckenberg Centre for Human Evolution and Palaeoecology   (Germany)

^d MAX PLANCK INSTITUTE FOR THE SCIENCE OF HUMAN HISTORY   (Germany)

^e HOSPITAL UNIVERSITARIO DR JOSÉ ELEUTERIO GONZÁLEZ   (Mexico)

^f LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

Comparative genomics; Genome sequencing; Mycobacterium leprae; Mycobacterium lepromatosis; Reductive evolution

Indexed keywords

BEDAQUILINE; BENZOTHIAZINONE DERIVATIVE; DAPSONE; Q 203; QUINOLONE DERIVATIVE; RIFAMPICIN; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; BACTERIAL DNA;

AMINO ACID SYNTHESIS; ARTICLE; BACTERIAL GENOME; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; LEPROMATOUS LEPROSY; MAJOR CLINICAL STUDY; MEXICO; MOLECULAR EVOLUTION; MOLECULAR PHYLOGENY; MYCOBACTERIUM; MYCOBACTERIUM LEPRAE; MYCOBACTERIUM LEPROMATOSIS; NEUROPATHOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL NERVOUS SYSTEM; PHYLOGEOGRAPHY; PRIORITY JOURNAL; PSEUDOGENE; SCHWANN CELL; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN BIOPSY; SPECIES DIFFERENCE; BIOPSY; CHROMOSOMAL MAPPING; CONTIG MAPPING; DNA SEQUENCE; GENETICS; GENOMICS; GEOGRAPHY; LEPROSY; MICROBIOLOGY; MOLECULAR GENETICS; PHYLOGENY; POLYMERASE CHAIN REACTION; PROCEDURES;

MYA; MYCOBACTERIUM; MYCOBACTERIUM LEPRAE;

BIOPSY; CHROMOSOME MAPPING; CONTIG MAPPING; DNA, BACTERIAL; EVOLUTION, MOLECULAR; GENOME, BACTERIAL; GENOMICS; GEOGRAPHY; HUMANS; LEPROSY; MEXICO; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM; PHYLOGENY; PHYLOGEOGRAPHY; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA; SPECIES SPECIFICITY;

EID: 84928787997     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1421504112     Document Type: Article

References (56)

1. World Health Organization (2013) Global leprosy: Update on the 2012 situation. Wkly Epidemiol Rec 88(35):365-379.
2. Ridley DS, Jopling WH (1966) Classification of leprosy according to immunity. A fivegroup system. Int J Lepr Other Mycobact Dis 34(3):255-273.
3. Britton WJ, Lockwood DN (2004) Leprosy. Lancet 363(9416):1209-1219.
4. Scollard DM, et al. (2006) The continuing challenges of leprosy. Clin Microbiol Rev 19(2):338-381.
5. Lucio R, Alsarado Y (1852) Opusculo sobre el mal de San Làzaro, ó elefanciasis de los griegos, escrito por los profesores de medicina y cirugia (Imprento de M. Murguia y Compañia, Mexico City, Mexico).
6. Latapi F, Chevez-Zamora A (1948) The "spotted" leprosy of Lucio: An introduction to its clinical and histological study. Int J Lepr 16:421-437.
7. Rea TH (1979) Lucio's phenomenon: An overview. Lepr Rev 50(2):107-112.
8. Rea TH, Jerskey RS (2005) Clinical and histologic variations among thirty patients with Lucio's phenomenon and pure and primitive diffuse lepromatosis (Latapi's lepromatosis). Int J Lepr Other Mycobact Dis 73(3):169-188.
9. Moschella SL (1967) The lepra reaction with necrotizing skin lesions. A report of six cases. Arch Dermatol 95(6):565-575.
10. Romero A, Brenes, Ibarra A, Fallas M (1949) Clinical study of lepromatous leprosy in Costa Rica. Int J Lepr 17(1-2):27-33.
11. Vargas-Ocampo F (2007) Diffuse leprosy of Lucio and Latapí: A histologic study. Lepr Rev 78(3):248-260.
12. Sehgal VN (2005) Lucio's phenomenon/erythema necroticans. Int J Dermatol 44(7): 602-605.
13. Ang P, Tay Y-K, Ng S-K, Seow C-S (2003) Fatal Lucio's phenomenon in 2 patients with previously undiagnosed leprosy. J Am Acad Dermatol 48(6):958-961.
14. Peixoto AB, Portela PS, Leal FRP de C, Brotas AM, Rodrigues NC dos S (2013) Lucio's phenomenon. Case study of an exceptional response to treatment exclusively with multibacillary multidrug therapy. An Bras Dermatol 88(6, Suppl 1):93-96.
15. World Health Organization (2014) WHO Recommended MDT Regimens. Available at www.who.int/lep/mdt/regimens/en/. Accessed September 24, 2014.
16. Helmer KA, Fleischfresser I, Kucharski-Esmanhoto LD, Fillus Neto J, Santamaria JR (2004) The Lucio's phenomenon (necrotizing erythema) in pregnancy. An Bras Dermatol 79(2):205-210.
17. Cole ST, et al. (2001) Massive gene decay in the leprosy bacillus. Nature 409(6823): 1007-1011.
18. Williams DL, Gillis TP, Portaels F (1990) Geographically distinct isolates of Mycobacterium leprae exhibit no genotypic diversity by restriction fragment-length polymorphism analysis. Mol Microbiol 4(10):1653-1659.
19. Monot M, et al. (2009) Comparative genomic and phylogeographic analysis of Mycobacterium leprae. Nat Genet 41(12):1282-1289.
20. Schuenemann VJ, et al. (2013) Genome-wide comparison of medieval and modern Mycobacterium leprae. Science 341(6142):179-183.
21. Han XY, et al. (2008) A new Mycobacterium species causing diffuse lepromatous leprosy. Am J Clin Pathol 130(6):856-864.
22. Han XY, Sizer KC, Velarde-Félix JS, Frias-Castro LO, Vargas-Ocampo F (2012) The leprosy agents Mycobacterium lepromatosis and Mycobacterium leprae in Mexico. Int J Dermatol 51(8):952-959.
23. Han XY, Sizer KC, Tan H-H (2012) Identification of the leprosy agent Mycobacterium lepromatosis in Singapore. J Drugs Dermatol 11(2):168-172.
24. Jessamine PG, et al. (2012) Leprosy-like illness in a patient with Mycobacterium lepromatosis from Ontario, Canada. J Drugs Dermatol 11(2):229-233.
25. Monteiro R, et al. (2012) Lucio's phenomenon: Another case reported in Brazil. An Bras Dermatol 87(2):296-300.
26. Souza CS, Roselino AM, Figueiredo F, Foss NT (2000) Lucio's phenomenon: Clinical and therapeutic aspects. Int J Lepr Other Mycobact Dis 68(4):417-425.
27. Saoji V, Salodkar A (2001) Lucio leprosy with lucio phenomenon. Indian J Lepr 73(3): 267-272.
28. Thappa DM, Karthikeyan K, Kumar BJ (2002) Is it Lucio leprosy with Lucio phenomenon or something else? Indian J Lepr 74(2):161-166.
29. Kumari R, Thappa DM, Basu D (2008) A fatal case of Lucio phenomenon from India. Dermatol Online J 14(2):10.
30. Golchai J, Zargari O, Maboodi A, Maboodi A, Granmayeh S (2004) Lepromatous leprosy with extensive unusual ulcerations and cachexia. Is it the first case of Lucio's phenomenon from Iran? Int J Lepr Other Mycobact Dis 72(1):56-59.
31. Choon SE, Tey KE (2009) Lucio's phenomenon: A report of three cases seen in Johor, Malaysia. Int J Dermatol 48(9):984-988.
32. Vera-Cabrera L, et al. (2011) Case of diffuse lepromatous leprosy associated with "Mycobacterium lepromatosis". J Clin Microbiol 49(12):4366-4368.
33. Cole ST, Supply P, Honoré N (2001) Repetitive sequences in Mycobacterium leprae and their impact on genome plasticity. Lepr Rev 72(4):449-461.
34. Truman RW, et al. (2011) Probable zoonotic leprosy in the southern United States. N Engl J Med 364(17):1626-1633.
35. Stinear TP, et al. (2007) Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer. Genome Res 17(2):192-200.
36. Demangel C, Stinear TP, Cole ST (2009) Buruli ulcer: Reductive evolution enhances pathogenicity of Mycobacterium ulcerans. Nat Rev Microbiol 7(1):50-60.
37. Chu BC, et al. (2010) Siderophore uptake in bacteria and the battle for iron with the host; a bird's eye view. Biometals 23(4):601-611.
38. Braun V, Hantke K (2011) Recent insights into iron import by bacteria. Curr Opin Chem Biol 15(2):328-334.
39. De Voss JJ, et al. (2000) The salicylate-derived mycobactin siderophores of Mycobacterium tuberculosis are essential for growth in macrophages. Proc Natl Acad Sci USA 97(3):1252-1257.
40. Reddy PV, et al. (2013) Disruption of mycobactin biosynthesis leads to attenuation of Mycobacterium tuberculosis for growth and virulence. J Infect Dis 208(8):1255-1265.
41. Kai M, et al. (2013) Characteristic mutations found in the ML0411 gene of Mycobacterium leprae isolated in Northeast Asian countries. Infect Genet Evol 19:200-204.
42. Simeone R, et al. (2012) Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death. PLoS Pathog 8(2):e1002507.
43. Fortune SM, et al. (2005) Mutually dependent secretion of proteins required for mycobacterial virulence. Proc Natl Acad Sci USA 102(30):10676-10681.
44. Garces A, et al. (2010) EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity. PLoS Pathog 6(6):e1000957.
45. Stoop EJM, et al. (2011) Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component. Dis Model Mech 4(4):526-536.
46. Rambukkana A (2001) Molecular basis for the peripheral nerve predilection of Mycobacterium leprae. Curr Opin Microbiol 4(1):21-27.
47. Tabouret G, et al. (2010) Mycobacterium leprae phenolglycolipid-1 expressed by engineered M. bovis BCG modulates early interaction with human phagocytes. PLoS Pathog 6(10):e1001159.
48. de Souza MM, Netto EM, Nakatani M, Duthie MS (2014) Utility of recombinant proteins LID-1 and PADL in screening for Mycobacterium leprae infection and leprosy. Trans R Soc Trop Med Hyg 108(8):495-501.
49. Han XY, Jessurun J (2013) Severe leprosy reactions due to Mycobacterium lepromatosis. Am J Med Sci 345(1):65-69.
50. Han XY, et al. (2009) Comparative sequence analysis of Mycobacterium leprae and the new leprosy-causing Mycobacterium lepromatosis. J Bacteriol 191(19):6067-6074.
51. Bos KI, et al. (2014) Pre-Columbian mycobacterial genomes reveal seals as a source of New World human tuberculosis. Nature 514(7523):494-497.
52. Meredith A, et al. (2014) Leprosy in red squirrels in Scotland. Vet Rec 175(11):285-286.
53. Chacon R (October 8, 1999) In Mexico, field rats are secret delicacy. Miami Herald. Available at www.latinamericanstudies.org/mexico/rats.htm. Accessed October 16, 2014.
54. Chevreux B, Wetter T, Suhai S (1999) Genome sequence assembly using trace signals and additional sequence information. Computer Science and Biology: Proceedings of the German Conference on Bioinformatics (GCB), Vol 99, pp 45-56. Available at www.bioinfo.de/isb/gcb99/talks/chevreux/main.html.
55. Carver TJ, et al. (2005) ACT: The Artemis Comparison Tool. Bioinformatics 21(16): 3422-3423.
56. Tamura K, Stecher G, Peterson D, Filipski A, Kumar S (2013) MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. Mol Biol Evol 30(12):2725-2729.