메뉴 건너뛰기




Volumn 10, Issue 1, 2015, Pages

Clinical characteristics and prognostic factors of adult hemophagocytic syndrome patients: A retrospective study of increasing awareness of a disease from a single-center in China

Author keywords

Clinical characteristics; Hemophagocytic lymphohistiocytosis (HLH); Laboratory tests; Prognosis

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIBIOTIC AGENT; ASPARTATE AMINOTRANSFERASE; CREATININE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; DOXORUBICIN; ETOPOSIDE; FIBRINOGEN; FRESH FROZEN PLASMA; GANCICLOVIR; GLUCOCORTICOID; HEMOGLOBIN; LACTATE DEHYDROGENASE; VINCRISTINE; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT;

EID: 84928729463     PISSN: None     EISSN: 17501172     Source Type: Journal    
DOI: 10.1186/s13023-015-0224-y     Document Type: Article
Times cited : (80)

References (39)
  • 1
    • 84886727845 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis: Advances in pathophysiology, diagnosis, and treatment
    • Chandrakasan S, Filipovich AH. Hemophagocytic lymphohistiocytosis: advances in pathophysiology, diagnosis, and treatment. J Pediatr. 2013;163:1253-9.
    • (2013) J Pediatr. , vol.163 , pp. 1253-1259
    • Chandrakasan, S.1    Filipovich, A.H.2
  • 2
    • 84863209652 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis in adults: Diagnosis and treatment
    • Larroche C. Hemophagocytic lymphohistiocytosis in adults: diagnosis and treatment. Joint Bone Spine. 2012;79:356-61.
    • (2012) Joint Bone Spine. , vol.79 , pp. 356-361
    • Larroche, C.1
  • 4
    • 82955237596 scopus 로고    scopus 로고
    • Not all hemophagocytes are created equally: Appreciating the heterogeneity of the hemophagocytic syndromes
    • Canna SW, Behrens EM. Not all hemophagocytes are created equally: appreciating the heterogeneity of the hemophagocytic syndromes. Curr Opin Rheumatol. 2012;24:113-8.
    • (2012) Curr Opin Rheumatol. , vol.24 , pp. 113-118
    • Canna, S.W.1    Behrens, E.M.2
  • 5
    • 54449101721 scopus 로고    scopus 로고
    • Clinical features of haemophagocytic syndrome in patients with systemic autoimmune diseases: Analysis of 30 cases
    • Fukaya S, Yasuda S, Hashimoto T, Oku K, Kataoka H, Horita T, et al. Clinical features of haemophagocytic syndrome in patients with systemic autoimmune diseases: analysis of 30 cases. Rheumatology (Oxford). 2008;47:1686-91.
    • (2008) Rheumatology (Oxford) , vol.47 , pp. 1686-1691
    • Fukaya, S.1    Yasuda, S.2    Hashimoto, T.3    Oku, K.4    Kataoka, H.5    Horita, T.6
  • 6
    • 25444476747 scopus 로고    scopus 로고
    • The macrophage activation syndrome: A new entity, a potentially fatal complication of rheumatic disorders
    • Kuzmanova SI. The macrophage activation syndrome: a new entity, a potentially fatal complication of rheumatic disorders. Folia Med. 2005;47:21-5.
    • (2005) Folia Med. , vol.47 , pp. 21-25
    • Kuzmanova, S.I.1
  • 7
    • 84903132528 scopus 로고    scopus 로고
    • Hemophagocytic syndromes-an update
    • Janka GE, Lehmberg K. Hemophagocytic syndromes-an update. Blood Rev. 2014;28:135-42.
    • (2014) Blood Rev. , vol.28 , pp. 135-142
    • Janka, G.E.1    Lehmberg, K.2
  • 8
    • 84864474210 scopus 로고    scopus 로고
    • Quantification of Epstein-Barr virus DNA is helpful for evaluation of chronic active Epstein-Barr virus infection
    • Sakamoto Y, Mariya Y, Kubo K. Quantification of Epstein-Barr virus DNA is helpful for evaluation of chronic active Epstein-Barr virus infection. Tohoku J Exp Med. 2012;227:307-11.
    • (2012) Tohoku J Exp Med. , vol.227 , pp. 307-311
    • Sakamoto, Y.1    Mariya, Y.2    Kubo, K.3
  • 9
    • 84859096332 scopus 로고    scopus 로고
    • Diagnostic criteria and laboratory tests for disseminated intravascular coagulation
    • Kaneko T, Wada H. Diagnostic criteria and laboratory tests for disseminated intravascular coagulation. J Clin Exp Hematop. 2011;51:67-76.
    • (2011) J Clin Exp Hematop. , vol.51 , pp. 67-76
    • Kaneko, T.1    Wada, H.2
  • 10
    • 0036786375 scopus 로고    scopus 로고
    • Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation
    • Henter J-I, Samuelsson-Horne A, Aricò M, Egeler RM, Elinder G, Filipovich AH, et al. Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation. Blood. 2002;100:2367-73.
    • (2002) Blood , vol.100 , pp. 2367-2373
    • Henter, J.-I.1    Samuelsson-Horne, A.2    Aricò, M.3    Egeler, R.M.4    Elinder, G.5    Filipovich, A.H.6
  • 11
    • 77954244065 scopus 로고    scopus 로고
    • Alemtuzumab as a bridge to allogeneic SCT in atypical hemophagocytic lymphohistiocytosis
    • Strout MP, Seropian S, Berliner N. Alemtuzumab as a bridge to allogeneic SCT in atypical hemophagocytic lymphohistiocytosis. Nat Rev Clin Oncol. 2010;7:415-20.
    • (2010) Nat Rev Clin Oncol. , vol.7 , pp. 415-420
    • Strout, M.P.1    Seropian, S.2    Berliner, N.3
  • 12
    • 80055079785 scopus 로고    scopus 로고
    • Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: Long-term results of the HLH-94 treatment protocol
    • Trottestam H, Horne A, Arico M, Egeler RM, Filipovich AH, Gadner H, et al. Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol. Blood. 2011;118:4577-84.
    • (2011) Blood , vol.118 , pp. 4577-4584
    • Trottestam, H.1    Horne, A.2    Arico, M.3    Egeler, R.M.4    Filipovich, A.H.5    Gadner, H.6
  • 14
    • 82155184541 scopus 로고    scopus 로고
    • Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH
    • Zhang K, Jordan MB, Marsh RA, Johnson JA, Kissell D, Meller J, et al. Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH. Blood. 2011;118:5794-8.
    • (2011) Blood , vol.118 , pp. 5794-5798
    • Zhang, K.1    Jordan, M.B.2    Marsh, R.A.3    Johnson, J.A.4    Kissell, D.5    Meller, J.6
  • 15
    • 79953220496 scopus 로고    scopus 로고
    • Malignancy-associated hemophagocytic lymphohistiocytosis in adults: A retrospective populationbased analysis from a single center
    • Machaczka M, Vaktnas J, Klimkowska M, Hagglund H. Malignancy-associated hemophagocytic lymphohistiocytosis in adults: a retrospective populationbased analysis from a single center. Leuk Lymphoma. 2011;52:613-9.
    • (2011) Leuk Lymphoma. , vol.52 , pp. 613-619
    • Machaczka, M.1    Vaktnas, J.2    Klimkowska, M.3    Hagglund, H.4
  • 16
    • 34547691044 scopus 로고    scopus 로고
    • Hemophagocytic syndromes
    • Janka GE. Hemophagocytic syndromes. Blood Rev. 2007;21:245-53.
    • (2007) Blood Rev. , vol.21 , pp. 245-253
    • Janka, G.E.1
  • 17
    • 1442274795 scopus 로고    scopus 로고
    • Pathogenesis of hemophagocytic syndrome (HPS)
    • Larroche C, Mouthon L. Pathogenesis of hemophagocytic syndrome (HPS). Autoimmun Rev. 2004;3:69-75.
    • (2004) Autoimmun Rev. , vol.3 , pp. 69-75
    • Larroche, C.1    Mouthon, L.2
  • 18
    • 0029879812 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis. Report of 122 children from the International Registry: FHL Study Group of the Histiocyte Society
    • Arico M, Janka G, Fischer A, Henter JI, Blanche S, Elinder G, et al. Hemophagocytic lymphohistiocytosis. Report of 122 children from the International Registry: FHL Study Group of the Histiocyte Society. Leukemia. 1996;10:197-203.
    • (1996) Leukemia , vol.10 , pp. 197-203
    • Arico, M.1    Janka, G.2    Fischer, A.3    Henter, J.I.4    Blanche, S.5    Elinder, G.6
  • 19
    • 84877819974 scopus 로고    scopus 로고
    • Advances in understanding the pathogenesis of HLH
    • Usmani GN, Woda BA, Newburger PE. Advances in understanding the pathogenesis of HLH. Br J Haematol. 2013;161:609-22.
    • (2013) Br J Haematol. , vol.161 , pp. 609-622
    • Usmani, G.N.1    Woda, B.A.2    Newburger, P.E.3
  • 21
    • 28344436688 scopus 로고    scopus 로고
    • Life-threatening hemophagocytic syndromes: Current outcomes with hematopoietic stem cell transplantation
    • Filipovich AH. Life-threatening hemophagocytic syndromes: current outcomes with hematopoietic stem cell transplantation. Pediatr Transplant. 2005;9 Suppl 7:87-91.
    • (2005) Pediatr Transplant , vol.9 , pp. 87-91
    • Filipovich, A.H.1
  • 22
    • 0034025084 scopus 로고    scopus 로고
    • Molecular analysis of latent membrane protein 1 in patients with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in Japan
    • Tabata YS, Teramura T, Kuriyama K, Yagi T, Todo S, Sawada T, et al. Molecular analysis of latent membrane protein 1 in patients with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in Japan. Leuk Lymphoma. 2000;38:373-80.
    • (2000) Leuk Lymphoma. , vol.38 , pp. 373-380
    • Tabata, Y.S.1    Teramura, T.2    Kuriyama, K.3    Yagi, T.4    Todo, S.5    Sawada, T.6
  • 23
    • 84923105409 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis: Review of etiologies and management
    • George MR. Hemophagocytic lymphohistiocytosis: review of etiologies and management. J Blood Med. 2014;5:69-86.
    • (2014) J Blood Med. , vol.5 , pp. 69-86
    • George, M.R.1
  • 24
    • 2942572043 scopus 로고    scopus 로고
    • Longitudinal follow-up of patients with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis
    • Imashuku S, Teramura T, Tauchi H, Ishida Y, Otoh Y, Sawada M, et al. Longitudinal follow-up of patients with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. Haematologica. 2004;89:183-8.
    • (2004) Haematologica , vol.89 , pp. 183-188
    • Imashuku, S.1    Teramura, T.2    Tauchi, H.3    Ishida, Y.4    Otoh, Y.5    Sawada, M.6
  • 25
    • 80054048140 scopus 로고    scopus 로고
    • Unrelated bone marrow transplantation induced long-term remission in a patient with life-threatening Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis
    • Kunitomi A, Kimura H, Ito Y, Naitoh K, Noda N, Iida H, et al. Unrelated bone marrow transplantation induced long-term remission in a patient with life-threatening Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. J Clin Exp Hematop. 2011;51:57-61.
    • (2011) J Clin Exp Hematop. , vol.51 , pp. 57-61
    • Kunitomi, A.1    Kimura, H.2    Ito, Y.3    Naitoh, K.4    Noda, N.5    Iida, H.6
  • 26
    • 74849139257 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation for familial hemophagocytic lymphohistiocytosis and Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in Japan
    • Ohga S, Kudo K, Ishii E, Honjo S, Morimoto A, Osugi Y, et al. Hematopoietic stem cell transplantation for familial hemophagocytic lymphohistiocytosis and Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in Japan. Pediatr Blood Cancer. 2010;54:299-306.
    • (2010) Pediatr Blood Cancer , vol.54 , pp. 299-306
    • Ohga, S.1    Kudo, K.2    Ishii, E.3    Honjo, S.4    Morimoto, A.5    Osugi, Y.6
  • 27
    • 0030770948 scopus 로고    scopus 로고
    • Upregulation of tumor necrosis factor-alpha gene by Epstein-Barr virus and activation of macrophages in Epstein-Barr virus-infected T cells in the pathogenesis of hemophagocytic syndrome
    • Lay JD, Tsao CJ, Chen JY, Kadin ME, Su IJ. Upregulation of tumor necrosis factor-alpha gene by Epstein-Barr virus and activation of macrophages in Epstein-Barr virus-infected T cells in the pathogenesis of hemophagocytic syndrome. J Clin Invest. 1997;100:1969-79.
    • (1997) J Clin Invest. , vol.100 , pp. 1969-1979
    • Lay, J.D.1    Tsao, C.J.2    Chen, J.Y.3    Kadin, M.E.4    Su, I.J.5
  • 28
    • 38549096546 scopus 로고    scopus 로고
    • Clinical characteristics of T-cell lymphoma associated with hemophagocytic syndrome: Comparison of T-cell lymphoma with and without hemophagocytic syndrome
    • Tong H, Ren Y, Liu H, Xiao F, Mai W, Meng H, et al. Clinical characteristics of T-cell lymphoma associated with hemophagocytic syndrome: comparison of T-cell lymphoma with and without hemophagocytic syndrome. Leuk Lymphoma. 2008;49:81-7.
    • (2008) Leuk Lymphoma. , vol.49 , pp. 81-87
    • Tong, H.1    Ren, Y.2    Liu, H.3    Xiao, F.4    Mai, W.5    Meng, H.6
  • 29
    • 0026640540 scopus 로고
    • Detection of clonal Epstein-Barr virus in malignant proliferation of peripheral blood CD3+ CD8+ T cells
    • Chan LC, Srivastava G, Pittaluga S, Kwong YL, Liu HW, Yuen HL. Detection of clonal Epstein-Barr virus in malignant proliferation of peripheral blood CD3+ CD8+ T cells. Leukemia. 1992;6:952-6.
    • (1992) Leukemia. , vol.6 , pp. 952-956
    • Chan, L.C.1    Srivastava, G.2    Pittaluga, S.3    Kwong, Y.L.4    Liu, H.W.5    Yuen, H.L.6
  • 30
    • 0032521451 scopus 로고    scopus 로고
    • A syndrome of peripheral blood T-cell infection with Epstein-Barr virus (EBV) followed by EBV-positive T-cell lymphoma
    • Kanegane H, Bhatia K, Gutierrez M, Kaneda H, Wada T, Yachie A, et al. A syndrome of peripheral blood T-cell infection with Epstein-Barr virus (EBV) followed by EBV-positive T-cell lymphoma. Blood. 1998;91:2085-91.
    • (1998) Blood , vol.91 , pp. 2085-2091
    • Kanegane, H.1    Bhatia, K.2    Gutierrez, M.3    Kaneda, H.4    Wada, T.5    Yachie, A.6
  • 31
    • 84866293713 scopus 로고    scopus 로고
    • Successful treatment of recurrent malignancy-associated hemophagocytic lymphohistiocytosis with a modified HLH-94 immunochemotherapy and allogeneic stem cell transplantation
    • Machaczka M, Nahi H, Karbach H, Klimkowska M, Hagglund H. Successful treatment of recurrent malignancy-associated hemophagocytic lymphohistiocytosis with a modified HLH-94 immunochemotherapy and allogeneic stem cell transplantation. Med Oncol. 2012;29:1231-6.
    • (2012) Med Oncol. , vol.29 , pp. 1231-1236
    • Machaczka, M.1    Nahi, H.2    Karbach, H.3    Klimkowska, M.4    Hagglund, H.5
  • 33
    • 84895083284 scopus 로고    scopus 로고
    • Identification of clinical features of lymphoma-associated hemophagocytic syndrome (LAHS): An analysis of 69 patients with hemophagocytic syndrome from a single-center in central region of China
    • Li F, Li P, Zhang R, Yang G, Ji D, Huang X, et al. Identification of clinical features of lymphoma-associated hemophagocytic syndrome (LAHS): an analysis of 69 patients with hemophagocytic syndrome from a single-center in central region of China. Med Oncol. 2014;31:902.
    • (2014) Med Oncol. , vol.31 , pp. 902
    • Li, F.1    Li, P.2    Zhang, R.3    Yang, G.4    Ji, D.5    Huang, X.6
  • 34
    • 84893641958 scopus 로고    scopus 로고
    • Clinical and laboratory characteristics of severe fever with thrombocytopenia syndrome in Chinese patients
    • Weng Y, Chen N, Han Y, Xing Y, Li J. Clinical and laboratory characteristics of severe fever with thrombocytopenia syndrome in Chinese patients. Braz J Infect Dis. 2014;18:88-91.
    • (2014) Braz J Infect Dis. , vol.18 , pp. 88-91
    • Weng, Y.1    Chen, N.2    Han, Y.3    Xing, Y.4    Li, J.5
  • 35
    • 84929502921 scopus 로고    scopus 로고
    • Clinical characteristics of 192 adult hemophagocytic lymphohistiocytosis
    • Huang W, Wang Y, Wang J, Zhang J, Wu L, Li S, et al. [Clinical characteristics of 192 adult hemophagocytic lymphohistiocytosis]. Zhonghua Xue Ye Xue Za Zhi. 2014;35:796-801.
    • (2014) Zhonghua Xue Ye Xue Za Zhi. , vol.35 , pp. 796-801
    • Huang, W.1    Wang, Y.2    Wang, J.3    Zhang, J.4    Wu, L.5    Li, S.6
  • 36
    • 77949448549 scopus 로고    scopus 로고
    • Hemophagocytic lymphohistiocytosis (HLH) and related disorders
    • Filipovich AH. Hemophagocytic lymphohistiocytosis (HLH) and related disorders. Hematol Am Soc Hematol Educ Program. 2009:127-31. https://www.ncbi.nlm.nih.gov/pubmed/20008190.
    • (2009) Hematol Am Soc Hematol Educ Program , pp. 127-131
    • Filipovich, A.H.1
  • 37
    • 79959258419 scopus 로고    scopus 로고
    • Secondary hemophagocytic syndrome in adults: A case series of 18 patients in a single institution and a review of literature
    • Shabbir M, Lucas J, Lazarchick J, Shirai K. Secondary hemophagocytic syndrome in adults: a case series of 18 patients in a single institution and a review of literature. Hematol Oncol. 2011;29:100-6.
    • (2011) Hematol Oncol. , vol.29 , pp. 100-106
    • Shabbir, M.1    Lucas, J.2    Lazarchick, J.3    Shirai, K.4
  • 38
    • 84859211748 scopus 로고    scopus 로고
    • Serum ferritin is a cost-effective laboratory marker for hemophagocytic lymphohistiocytosis in the developing world
    • Switala JR, Hendricks M, Davidson A. Serum ferritin is a cost-effective laboratory marker for hemophagocytic lymphohistiocytosis in the developing world. J Pediatr Hematol Oncol. 2012;34:e89-92.
    • (2012) J Pediatr Hematol Oncol. , vol.34 , pp. e89-e92
    • Switala, J.R.1    Hendricks, M.2    Davidson, A.3
  • 39
    • 84922608677 scopus 로고    scopus 로고
    • Determination of an appropriate cut-off value for ferritin in the diagnosis of hemophagocytic lymphohistiocytosis
    • Lehmberg K, McClain KL, Janka GE, Allen CE. Determination of an appropriate cut-off value for ferritin in the diagnosis of hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2014;61:2101-3.
    • (2014) Pediatr Blood Cancer. , vol.61 , pp. 2101-2103
    • Lehmberg, K.1    McClain, K.L.2    Janka, G.E.3    Allen, C.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.