Molecular analysis of latent membrane protein 1 in patients with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in Japan

Leukemia and Lymphoma

Volumn 38, Issue 3-4, 2000, Pages 373-380

  Tabata, Yasuhiro ^a   Hibi, Shigeyoshi ^a   Teramura, Tomoko ^a   Kuriyama, Kikuko ^a   Yagi, Tomohito ^a   Todo, Shinjiro ^a   Sawada, Tadashi ^a   Imashuku, Shinsaku ^b  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b Kyoto City Institute of Health and Environmental Sciences   (Japan)

Author keywords

30 base pair deletion; Epstein Barr virus; Hemophagocytic lymphohistiocytosis; LMP1; NF B

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LATENT MEMBRANE PROTEIN 1; VIRUS DNA;

ADULT; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CHILD; CLINICAL ARTICLE; EPSTEIN BARR VIRUS; ERYTHROPHAGOCYTOSIS; FEMALE; GENE MUTATION; HISTIOCYTOSIS; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TANDEM REPEAT;

EID: 0034025084     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.3109/10428190009087028     Document Type: Article

References (33)

1. Kieff, E. (1996) Epstein-Barr virus and its replication. In B.N. Fields, D.M. Knipe, P.M. Howley (eds.), Virology, 3rd edn, Vol. 2, pp. 2343-2396. Philadelphia: Lippincott-Raven Publishers.
2. Su, I.J., and Chen, J.Y. (1997) The role of Epstein-Barr virus in lymphoid malignancies. Critical Reviews in Oncology/Hematology, 26, 25-41.
3. Anagnostopoulos, I., Hummel, M. and Stein, H. (1995) Frequent presence of latent Epstein-Barr virus infection in peripheral T cell lymphomas. A review. Leukemia & Lymphoma, 19, 1-12.
4. Liebowitz, D. (1998) Epstein-Barr virus and a cellular signaling pathway in lymphomas from immunosuppressed patients. New England Journal of Medicine, 338, 1413-1421.
5. Hu, L.F., Zabarovsky, E.R., Chen, F., Cao, S.L., Ernberg, I., Klein, G. and Winberg, G. (1991) Isolation and sequence of the Epstein-Barr virus BNLF-1 gene (LMP1) from a Chinese nasopharyngeal carcinoma. Journal of General Virology, 72, 2399-2409.
6. Knecht, H., Bachmann, E., Brousset, P., Rothenberger, S., Einsele, H., Lestou, V.S., Delsol, G., Bachmann, F., Ambros, P.F. and Odermatt, B.F. (1995) Mutational hot spots within the carboxy terminal region of the LMP1 oncogene of Epstein-Barr virus are frequent in lymphoproliferative disorders. Oncogene, 10, 523-528.
7. Kingma, D.W., Weiss, W.B., Jaffe, E.S., Kumar, S., Frekko, K. and Raffeld, M. (1996) Epstein-Barr virus latent membrane protein-1 oncogene deletions: correlations with malignancy in Epstein-Barr virus-associated lymphoproliferative disorders and malignant lymphomas. Blood, 88, 242-251.
8. Henter, J.I., Elinder, G. and Ost, A. (1991) Diagnostic guidelines for hemophagocytic lymphohistiocytosis. Seminar in Oncology, 18, 29-33.
9. Imashuku, S. (1997) Differential diagnosis of hemophagocytic syndrome: underlying disorders and selection of the most effective treatment. International Journal of Hematology, 66, 135-151.
10. Imashuku, S., Hibi, S., Morinaga, S., Takagi, K., Chen, J., Mugishima, H., Ishii, T., Sako, M., Arakawa, H. and Kato, M. (1997) Haemophagocytic lymphohistiocytosis in association with granular lymphocyte proliferative disorders in early childhood: characteristic bone marrow morphology. British Journal of Haematology, 96, 708-714.
11. Imashuku, S., Hibi, S. and Todo, S. (1997) Hemophagocytic lymphohistiocytosis in infancy and childhood. Journal of Pediatrics, 130, 352-357.
12. Yao, M., Cheng, A.L., Su, I.J., Lin, M.T., Uen, W.C., Tien, H.F., Wang, C.H. and Chen, Y.C. (1994) Clinicopathological spectrum of haemophagocytic syndrome in Epstein-Barr virus-associated peripheral T-cell lymphoma. British Journal of Haematology, 87, 535-43.
13. Imashuku, S., Hibi, S., Tabata, Y., Sako, M., Sekine, Y., Hirayama, K., Sakazaki, H., Maeda, N., Kito, H., Shichino, H. and Mugishima, H. (1998) Biomarker and morphological characteristics of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis. Medical and Pediatric Oncology, 31, 131-137.
14. Kawaguchi, H., Miyashita, T., Herbst, H., Niedobitek, G., Asada, M., Tsuchida, M., Hanada, R., Kinoshita, A., Sakurai, M., Kobayashi, N. and Mizutani, S. (1993) Epstein-Barr virus-infected T lymphocytes in Epstein-Barr virus-associated hemophagocytic syndrome. Journal of Clinical Investigation, 92, 1444-1450.
15. Teshima, T., Miyaji, R., Fukuda, M., Ohshima, K. (1996) Bone-marrow transplantation for Epstein-Barr-virus-associated natural killer cell-large granular lymphocyte leukaemia. Lancet 347, 1124.
16. Imashuku, S., Hibi, S., Fujiwara, F., Ikushima, S. and Todo, S. (1994) Haemophagocytic lymphohistiocytosis, interferon-gamma-naemia and Epstein-Barr virus involvement. British Journal of Haematology, 88, 656-658.
17. Chen, R.L., Lin, K.H., Lin, D.T., Su, I.J., Huang, L.M., Lee, P.I., Hseih, K.H., Lin, K.S. and Lee, C.Y. (1995) Immunomodulation treatment for childhood virus-associated haemophagocytic lymphohistiocytosis. British Journal of Haematology, 89, 282-290.
18. Dolezal, M.V., Kamel, O.W., van de Rijn, M., Cleary, M.L., Sibley, R.K. and Warnke, R.A. (1995) Virus-associated hemophagocytic syndrome characterized by clonal Epstein-Barr virus genome. American Journal of Clinical Pathology, 103, 189-194.
19. Chen, J.S., Lin, K.H., Lin, D.T., Chen, R.L., Jou, S.T. and Su, I.J. (1998) Longitudinal observation and outcome of nonfamilial childhood haemophagocytic syndrome receiving etoposide-containing regimens. British Journal of Haematology, 103, 756-762.
20. Imashuku, S., Hibi, S., Ohara, T., Iwai, A., Sako, M., Kato, M., Arakawa, H., Sotomatsu, M., Kataoka, S., Asami, K., Hasegawa, D., Kosaka, Y., Sano, K., Igarashi, N., Maruhashi, K., Ichimi, R., Kawasaki, H., Maeda, N., Tanizawa, A., Arai, K., Abe, T., Hisakawa, H., Miyashita, H. and Henter, J.I. for the Histiocyte Society. (1999) Effective control of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis with immunochemotherapy. Blood, 93, 1869-1874.
21. Raab-Traub, N. and Flynn, K. (1986) The structure of the termini of the Epstein-Barr virus as a marker of clonal cellular proliferation. Cell, 47, 883-889.
22. Henter, J.I., Arico, M., Egeler, R.M., Elinder, G., Favara, B.E., Filipovich, A.H., Gadner, H., Imashuku, S., Janka-Schaub, G., Komp, D., Ladisch, S. and Webb, D. (1997) HLH-94: a treatment protocol for hemophagocytic lymphohistiocytosis. HLH study group of the Histiocyte Society. Medical and Pediatric Oncology, 28, 342-347.
23. Mazda, O., Satoh, E., Yasutomi, K. and Imanishi, J. (1997) Extremely efficient gene transfection into lympho-hematopoietic cell lines by Epstein-Barr virus-based vectors. Journal of Immunological Methods, 204, 143-151.
24. Martin, J. and Sugden, B. (1991) The latent membrane protein oncoprotein resembles growth factor receptors in the properties of its turnover. Cell Growth and Differentiation, 2, 653-660.
25. Chen, M.L., Tsai, C.N., Liang, C.L., Shu, C.H., Huang, C.R., Sulitzeanu, D., Liu, S.T. and Chang, Y.S. (1992) Cloning and characterization of the latent membrane protein (LMP) of a specific Epstein-Barr virus variant derived from the nasopharyngeal carcinoma in the Taiwanese population. Oncogene, 7, 2131-2140.
26. Imashuku, S., Hibi, S., Fujiwara, F. and Todo, S. (1996) Hyper-interleukin (IL)-6-naemia in haemophagocytic lymphohistiocytosis. British Journal of Haematology, 93, 803-807.
27. Johnson, R.J., Stack, M., Hazlewood, S.A., Jones, M., Blackmore, C.G., Hu, L. F. and Rowe, M. (1998) The 30-base-pair deletion in Chinese variants of Epstein-Barr virus LMP1 gene is not the major effector of functional differences between variant LMP1 genes in human lymphocytes. Journal of Virology, 72, 4038-4048.
28. Miller, W.E., Cheshire, J.L., Baldwin, A.S. Jr and Raab-Traub, N. (1998) The NPC derived C15 LMP1 protein confers enhanced activation of NF-κB and induction of the EGFR in epithelial cells. Oncogene, 16, 1869-1877.
29. Barnes, P.J. and Karin, M. (1997) Nuclear factor-κB - a pivotal transcription factor in chronic inflammatory diseases. New England Journal of Medicine, 336, 1066-1071.
30. Hayashi, K., Chen, W.G., Chen, Y.Y., Bacchi, M.M., Bacchi, C.E., Alvarenga, M., Abreu, E.S., Chang, K.L. and Weiss, L.M. (1997) Deletion of Epstein-Barr virus latent membrane protein 1 gene in United States and Brazilian Hodgkin's disease and reactive lymphoid tissue: high frequency of a 30-bp deletion. Human Pathology, 28, 1408-1414.
31. Berger, C., McQuain, C., Sullivan, J.L., Nadal, D., Quesenberry, P.J. and Knecht, H. (1997) The 30-bp deletion variant of Epstein-Barr virus-encoded latent membrane protein-1 prevails in acute infectious mononucleosis. Journal of Infectious Disease, 176, 1370-1373.
32. Itakura, O., Yamada, S., Narita, M. and Kikuta, H. (1996) High prevalence of a 30-base pair deletion and single-base mutations within the carboxy terminal end of the LMP-1 oncogene of Epstein-Barr virus in the Japanese population. Oncogene, 13, 1549-1553.
33. Khanim, F., Yao, Q.Y., Niedobitek, G., Sihota, S., Rickinson, A.B. and Young, L. S. (1996) Analysis of Epstein-Barr virus gene polymorphisms in normal donors and in virus-associated tumors from different geographic locations. Blood, 88, 3491-3501.