Sodium nitrite potentiates renal oxidative stress and injury in hemoglobin exposed guinea pigs

Toxicology

Volumn 333, Issue , 2015, Pages 89-99

  Baek, Jin Hyen ^a   Zhang, Xiaoyuan ^a   Williams, Matthew C ^a   Hicks, Wayne ^a   Buehler, Paul W ^a   D'Agnillo, Felice ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

Biomarkers; Heme; Hemoglobin; Kidney; Nitrite; Oxidative stress

Indexed keywords

BIOLOGICAL MARKER; HEME OXYGENASE 1; HEMOGLOBIN; IRON; KIDNEY INJURY MARKER 1; SODIUM NITRITE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; FATTY ACID BINDING PROTEIN; METHEMOGLOBIN; NITRIC ACID DERIVATIVE; SODIUM NITRATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL DEATH; CONTROLLED STUDY; GUINEA PIG; HEMOGLOBIN BLOOD LEVEL; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; KIDNEY CELL; KIDNEY CORTEX; KIDNEY HOMOGENATE; KIDNEY INJURY; KIDNEY TUBULE CELL; LIPID PEROXIDATION; MACROPHAGE ACTIVATION; MALE; METHEMOGLOBINEMIA; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; ACUTE KIDNEY FAILURE; ANIMAL; BLOOD; CHEMICALLY INDUCED; DOSE RESPONSE; DRUG EFFECTS; DRUG POTENTIATION; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY; TIME;

CAVIA;

ACUTE KIDNEY INJURY; ANIMALS; BIOLOGICAL MARKERS; CELL DEATH; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FATTY ACID-BINDING PROTEINS; GUINEA PIGS; HEME OXYGENASE-1; HEMOGLOBINS; INFUSIONS, INTRAVENOUS; KIDNEY; LIPID PEROXIDATION; MALE; METHEMOGLOBIN; METHEMOGLOBINEMIA; NF-E2-RELATED FACTOR 2; NITRATES; OXIDATION-REDUCTION; OXIDATIVE STRESS; TIME FACTORS;

EID: 84928728175     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2015.04.007     Document Type: Article

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