Serum Vitamin D levels and Vitamin D supplementation do not correlate with the severity of chronic eczema in children

European Annals of Allergy and Clinical Immunology

Volumn 47, Issue 2, 2015, Pages 41-47

  Galli, Elena ^a   Rocchi, L ^a   Carello, R ^a   Giampietro, P G ^a   Panei, P ^b   Meglio, P ^a  

^a FATEBENEFRATELLI HOSPITAL   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

IgE chronic eczema; Not IgE chronic eczema; Serum vitamin D levels; Vit D supplementation

Indexed keywords

25 HYDROXYVITAMIN D; COLECALCIFEROL; IMMUNOGLOBULIN E; BIOLOGICAL MARKER; CALCIFEDIOL;

ADOLESCENT; ARTICLE; CHILD; CHRONIC DISEASE; CONTROLLED STUDY; DISEASE SEVERITY; ECZEMA; FEMALE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SENSITIZATION; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION; AGE; BLOOD; DIET SUPPLEMENTATION; IMMUNOLOGY; ITALY; PRESCHOOL CHILD; SEVERITY OF ILLNESS INDEX; TIME; TREATMENT OUTCOME;

ADOLESCENT; AGE FACTORS; BIOLOGICAL MARKERS; CALCIFEDIOL; CHILD; CHILD, PRESCHOOL; CHRONIC DISEASE; DIETARY SUPPLEMENTS; ECZEMA; FEMALE; HUMANS; IMMUNOGLOBULIN E; INFANT; MALE; ROME; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TREATMENT OUTCOME;

EID: 84928696460     PISSN: 17641489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Flohr C, Mann J. New insights into the epidemiology of childhood atopic dermatitis. Allergy. 2014:69:3-16.
2. Meglio P, Galli E, Maiello N. Atopic dermatitis In ERS Handbook: Paediatric Respiratory Medicine, eds. Eber E., Midulla F. 2013;363-9.
3. Schneider L, Tilles S, Lio P, et al. Atopic dermatitis: a practice parameter update 2012. J Allergy Clin Immunol. 2013;131:295-9.
4. De Benedetto A, Kubo A, Beck LA. Skin barrier disruption: a requirement for allergen sensitization? J Invest Dermatol. 2012;132:949-63.
5. Park CO, Noh S, Jin S, et al. Insight into newly discovered innate immune modulation in atopic dermatitis. Exp Dermatol. 2013:22:6-9.
6. Hewison M. Vitamin D and innate and adaptive immunity. Vitam Horm. 2011;86:23-62.
7. Muehleisen B and Gallo RL. Vitamin D in allergic disease: shedding light on a complex problem. J Allergy Clin Immunol. 2013;131:324-329.
8. Von Gunten S, Cortinas-Elizondo F, Kollarik M, et al. Mechanisms and potential therapeutic targets in allergic inflammation: recent insights. Allergy. 2013;68:1487-98.
9. Hanifin JM, Rajka G. Diagnostic features of atopicdermatitis. Acta Dermatol Venereol. 1980;92:44-7.
10. Severity scoring of atopic dermatitis: the SCORAD index. Consensus Report of the European Task Force on Atopic Dermatitis. Dermatology. 1993;186:23-31.
11. Misra M, Pacaud D, Petryk A, et al. Vitamin D deficiency in children and its management: review of current knowledge and recommendations. Pediatrics. 2008;122:398-17.
12. Thacher TD, Clarke BL. Vitamin D insufficiency. Mayo Clin Proc. 2011;86:50-60.
13. Jinnestål CL, Belfrage E, Bäck O, et al. Skin barrier impairment correlates with cutaneous Staphylococcus aureus colonization and sensitization to skin-associated microbial antigens in adult patients with atopic dermatitis. Int J Dermatol. 2014;53:27-33.
14. Liu PT, Stenger S, Li H, et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science. 2006;311:1770-3.
15. Hollams EM. Vitamin D and atopy and asthma phenotypes in children. Curr Opin Allergy Clin Immunol. 2012;12:228-34.
16. Roider E, Ruzicka T, Schauber J. Vitamin D, the cutaneous barrier, antimicrobial peptides and allergies: is there a link? Allergy Asthma Immunol Res. 2013;5:119-28.
17. Benson AA, Toh JA, Vernon N, et al. The role of vitamin D in the immunopathogenesis of allergic skin diseases. Allergy. 2012;67:296-301.
18. Mutgi K, Koo J. Update on the role of systemic vitamin D in atopic dermatitis. Pediatr Dermatol. 2012;30:303-7.
19. Mesquita Kde C, Igreja AC, Costa IM. Atopic dermatitis and vitamin D: facts and controversies. An Bras Dermatol. 2013;88:945-53.
20. Peroni DG, Piacentini GL, Cametti E, et al. Correlation between serum 25-hydroxyvitamin D levels and severity of atopic dermatitis in children. Br J Dermatol. 2011;164:1078-82.
21. Heimbeck I, Wjst M, Apfelbacher CJ. Low vitamin D serum level is inversely associated with eczema in children and adolescents in Germany. Allergy. 2013;68:906-10.
22. Wang SS, Hon KL, Kong AP, et al. Vitamin D deficiency is associated with diagnosis and severity of childhood atopic dermatitis. Pediatr Allergy Immunol. 2014;25:30-5.
23. Lee SA, Hong S, Kim HJ, et al. Correlation between serum vitamin D level and the severity of atopic dermatitis associated with food sensitization. Allergy Asthma Immunol Res. 2013;5:207-10.
24. Akan A, Azkur D, Ginis T, et al. Vitamin D level in children is correlated with severity of atopic dermatitis but only in patients with allergic sensitizations. Pediatr Dermatol. 2013;30:359-63.
25. Chiu YE, Havens PL, Siegel DH, et al. Serum 25-hydroxyvitamin D concentration does not correlate with atopic dermatitis severity. J Am Acad Dermatol. 2013;69:40-6.
26. Hata TR, Kotol P, Jackson M, et al. Administration of oral vitamin D induces cathelicidin production in atopic individuals. J Allergy Clin Immunol. 2008;122:829-31.
27. Sidbury R, Sullivan AF, Thadhani RI, et al. Randomized controlled trial of vitamin D supplementation for winter-related atopic dermatitis in Boston: a pilot study. Br J Dermatol. 2008;159:245-7.
28. Javanbakht MH, Keshavarz SA, Djalali M, et al. Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis. J Dermatol Treat. 2011;22:144-50.
29. Amestejani M, Salehi BS, Vasigh M, et al. Vitamin D supplementation in the treatment of atopic dermatitis: a clinical trial study. J Drugs Dermatol. 2012;11:327-30.
30. Hata TR, Audish D, Kotol P, et al. A randomized controlled double-blind investigation of the effects of vitamin D dietary supplementation in subjects with atopic dermatitis. J Eur Acad Dermatol Venereol. 2014;28:781-9.
31. Samochocki Z, Bogaczewicz J, Jeziorkowska R, et al. Vitamin D effects in atopic dermatitis. J Am Acad Dermatol. 2013;69:238-44.