Update on the role of systemic vitamin D in atopic dermatitis

Pediatric Dermatology

Volumn 30, Issue 3, 2013, Pages 303-307

  Mutgi, Krishna ^a   Koo, John ^b  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA DEFENSIN; CATHELICIDIN; FILAGGRIN; INVOLUCRIN; POLYPEPTIDE ANTIBIOTIC AGENT; VITAMIN D; VITAMIN D RECEPTOR;

ATOPIC DERMATITIS; CALCIUM HOMEOSTASIS; DISEASE SEVERITY; DOSE RESPONSE; HUMAN; IMMUNOMODULATION; KERATINOCYTE; MACROPHAGE; NONHUMAN; PHOTOTHERAPY; PREVALENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SYSTEMATIC REVIEW; ULTRAVIOLET B RADIATION; UPREGULATION; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; VITAMIN SUPPLEMENTATION;

ANIMALS; CHILD; DERMATITIS, ATOPIC; HUMANS; VITAMIN D; VITAMINS;

EID: 84876944976     PISSN: 07368046     EISSN: 15251470     Source Type: Journal    
DOI: 10.1111/j.1525-1470.2012.01850.x     Document Type: Review

References (18)

1. Zeppa L, Bellini V, Lisi P,. Atopic dermatitis in adults. Dermatitis 2011; 22: 40-46.
2. Spergel JM,. Epidemiology of atopic dermatitis and atopic march in children. Immunol Allergy Clin North Am, 2010; 30: 269-280.
3. Boguniewicz M, Leung DY,. Atopic dermatitis: a disease of altered skin barrier and immune dysregulation. Immunol Rev 2011; 242: 233-246.
4. Palmer CN, Irvine AD, Terron-Kwiatkowski A, et al., Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nat Genet 2006; 38: 441-446.
5. Etten EV, Mathieu C,. Immunoregulation by 1,25-dihydroxyvitamin D3: basic concepts. J Steroid Biochem Mol Biol, 2005; 97: 93-101.
6. Oren E, Banerji A, Camargo CA,. Vitamin D and atopic disorders in an obese population screened for vitamin D deficiency. J Allergy Clin Immunol 2008; 121: 533-534.
7. Peroni D, Piacentini G, Cametti E, et al., Correlation between serum 25-hydroxy-vitamin D levels and severity of atopic dermatitis in children. Br J Dermatol 2011; 164: 1078-1082.
8. Rehal B, Armstrong A,. Health outcome measures in atopic dermatitis: a systematic review of trends in disease severity and quality-of-life instruments 1985-2010. PLoS ONE 2011; 6: e17520.
9. Solvoll K, Syland E, Sandstad B, et al., Dietary habits among patients with atopic dermatitis. Eur J Clin Nutr 2000; 54: 93-97. (Pubitemid 30162878)
10. Sidbury R, Sullivan A, Thadhani R, et al., Randomized controlled trial of vitamin D supplementation for winter-related atopic dermatitis in Boston: a pilot study. Br J Dermatol 2008; 159: 245-247. (Pubitemid 351874486)
11. Javanbakht MH, Keshavarz SA, Djalali M, et al., Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis. J Dermatolog Treat 2010; 22: 144-150.
12. Amestejani M, Salehi BS, Vasigh M, et al., Vitamin D supplementation in the treatment of atopic dermatitis: a clinical trial study. J Drugs Dermatol 2012; 11: 327-330.
13. Vähävihu K, Ylianttila L, Salmelin R, et al., Heliotherapy improves vitamin D balance and atopic dermatitis. Br J Dermatol 2008; 158: 1323-1328. (Pubitemid 351692863)
14. Vähävihu K, Ala-Houhala M, Peric M, et al., Narrowband ultraviolet B treatment improves vitamin D balance and alters antimicrobial peptide expression in skin lesions of psoriasis and atopic dermatitis. Br J Dermatol 2010; 163: 321-328.
15. Hong SP, Kim MJ, Jung M, et al., Biopositive effects of low-dose UVB on epidermis: coordinate upregulation of antimicrobial peptides and permeability barrier reinforcement. J Invest Dermatol 2008; 128: 2880-2887.
16. Bals R,. Epithelial antimicrobial peptides in host defense against infection. Respir Res 2000; 1: 141-150.
17. Hata TR, Kotol P, Jackson M, et al., Administration of oral vitamin D induces cathelicidin production in atopic individuals. J Allergy Clin Immunol 2008; 122: 829-831.
18. Büchau AS, MacLeod DT, Morizane S, et al., Bcl-3 acts as an innate immune modulator by controlling antimicrobial responses in keratinocytes. J Invest Dermatol 2009; 129: 2148-2155.