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Volumn 158, Issue 2, 2015, Pages 183-192

The cation channel Trpv2 is a new suppressor of arthritis severity, joint damage, and synovial fibroblast invasion

Author keywords

Angiogenesis; Arthritis; Autoimmunity; Ion channels; Pathogenesis; Synovitis

Indexed keywords

CALCIUM; GELATINASE A; INTERLEUKIN 1BETA; STROMELYSIN; VANILLOID RECEPTOR 2; CALCIUM CHANNEL; CANNABIDIOL; CANNABINOID; COLLAGEN; O-1821 COMPOUND; PRISTANE; SMALL INTERFERING RNA; TERPENE; TRPV2 PROTEIN, HUMAN; TRPV2 PROTEIN, MOUSE; TRPV2 PROTEIN, RAT; VANILLOID RECEPTOR;

EID: 84928609702     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2015.04.001     Document Type: Article
Times cited : (34)

References (47)
  • 5
    • 73249125200 scopus 로고    scopus 로고
    • Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis
    • Bartok B., Firestein G.S. Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis. Immunol. Rev. 2010, 233(1):233-255.
    • (2010) Immunol. Rev. , vol.233 , Issue.1 , pp. 233-255
    • Bartok, B.1    Firestein, G.S.2
  • 6
    • 22244468716 scopus 로고    scopus 로고
    • Invasiveness of fibroblast-like synoviocytes is an individual patient characteristic associated with the rate of joint destruction in patients with rheumatoid arthritis
    • Tolboom T.C., van der Helm-Van Mil A.H., Nelissen R.G., Breedveld F.C., Toes R.E., Huizinga T.W. Invasiveness of fibroblast-like synoviocytes is an individual patient characteristic associated with the rate of joint destruction in patients with rheumatoid arthritis. Arthritis Rheum. 2005, 52(7):1999-2002.
    • (2005) Arthritis Rheum. , vol.52 , Issue.7 , pp. 1999-2002
    • Tolboom, T.C.1    van der Helm-Van Mil, A.H.2    Nelissen, R.G.3    Breedveld, F.C.4    Toes, R.E.5    Huizinga, T.W.6
  • 7
    • 49449095162 scopus 로고    scopus 로고
    • The arthritis severity locus Cia5d is a novel genetic regulator of the invasive properties of synovial fibroblasts
    • Laragione T., Brenner M., Mello A., Symons M., Gulko P.S. The arthritis severity locus Cia5d is a novel genetic regulator of the invasive properties of synovial fibroblasts. Arthritis Rheum. 2008, 58(8):2296-2306.
    • (2008) Arthritis Rheum. , vol.58 , Issue.8 , pp. 2296-2306
    • Laragione, T.1    Brenner, M.2    Mello, A.3    Symons, M.4    Gulko, P.S.5
  • 8
    • 77956633322 scopus 로고    scopus 로고
    • MTOR regulates the invasive properties of synovial fibroblasts in rheumatoid arthritis
    • Laragione T., Gulko P.S. mTOR regulates the invasive properties of synovial fibroblasts in rheumatoid arthritis. Mol. Med. 2010, 16(9-10):352-358.
    • (2010) Mol. Med. , vol.16 , Issue.9-10 , pp. 352-358
    • Laragione, T.1    Gulko, P.S.2
  • 9
    • 35548981028 scopus 로고    scopus 로고
    • Contribution of genetic studies in rodent models of autoimmune arthritis to understanding and treatment of rheumatoid arthritis
    • Gulko P.S. Contribution of genetic studies in rodent models of autoimmune arthritis to understanding and treatment of rheumatoid arthritis. Genes Immun. 2007, 8(7):523-531.
    • (2007) Genes Immun. , vol.8 , Issue.7 , pp. 523-531
    • Gulko, P.S.1
  • 10
    • 52449122907 scopus 로고    scopus 로고
    • Cia5d regulates a new fibroblast-like synoviocyte invasion-associated gene expression signature
    • Laragione T., Brenner M., Li W., Gulko P.S. Cia5d regulates a new fibroblast-like synoviocyte invasion-associated gene expression signature. Arthritis Res. Ther. 2008, 10(4):R92.
    • (2008) Arthritis Res. Ther. , vol.10 , Issue.4 , pp. R92
    • Laragione, T.1    Brenner, M.2    Li, W.3    Gulko, P.S.4
  • 11
    • 34250755449 scopus 로고    scopus 로고
    • Expression of transient receptor potential vanilloid 1 (TRPV1) in synovial fibroblasts from patients with osteoarthritis and rheumatoid arthritis
    • Engler A., Aeschlimann A., Simmen B.R., Michel B.A., Gay R.E., Gay S., Sprott H. Expression of transient receptor potential vanilloid 1 (TRPV1) in synovial fibroblasts from patients with osteoarthritis and rheumatoid arthritis. Biochem. Biophys. Res. Commun. 2007, 359(4):884-888.
    • (2007) Biochem. Biophys. Res. Commun. , vol.359 , Issue.4 , pp. 884-888
    • Engler, A.1    Aeschlimann, A.2    Simmen, B.R.3    Michel, B.A.4    Gay, R.E.5    Gay, S.6    Sprott, H.7
  • 12
    • 33748418461 scopus 로고    scopus 로고
    • Thermosensitive TRP ion channels mediate cytosolic calcium response in human synoviocytes
    • Kochukov M.Y., McNearney T.A., Fu Y., Westlund K.N. Thermosensitive TRP ion channels mediate cytosolic calcium response in human synoviocytes. Am. J. Physiol. Cell Physiol. 2006, 291(3):C424-C432.
    • (2006) Am. J. Physiol. Cell Physiol. , vol.291 , Issue.3 , pp. C424-C432
    • Kochukov, M.Y.1    McNearney, T.A.2    Fu, Y.3    Westlund, K.N.4
  • 15
    • 0033119629 scopus 로고    scopus 로고
    • A capsaicin-receptor homologue with a high threshold for noxious heat
    • Caterina M.J., Rosen T.A., Tominaga M., Brake A.J., Julius D. A capsaicin-receptor homologue with a high threshold for noxious heat. Nature 1999, 398(6726):436-441.
    • (1999) Nature , vol.398 , Issue.6726 , pp. 436-441
    • Caterina, M.J.1    Rosen, T.A.2    Tominaga, M.3    Brake, A.J.4    Julius, D.5
  • 17
    • 0029905940 scopus 로고    scopus 로고
    • Pristane-induced arthritis in rats: a new model for rheumatoid arthritis with a chronic disease course influenced by both major histocompatibility complex and non-major histocompatibility complex genes
    • Vingsbo C., Sahlstrand P., Brun J.G., Jonsson R., Saxne T., Holmdahl R. Pristane-induced arthritis in rats: a new model for rheumatoid arthritis with a chronic disease course influenced by both major histocompatibility complex and non-major histocompatibility complex genes. Am. J. Pathol. 1996, 149(5):1675-1683.
    • (1996) Am. J. Pathol. , vol.149 , Issue.5 , pp. 1675-1683
    • Vingsbo, C.1    Sahlstrand, P.2    Brun, J.G.3    Jonsson, R.4    Saxne, T.5    Holmdahl, R.6
  • 18
    • 12344258596 scopus 로고    scopus 로고
    • The non-MHC quantitative trait locus Cia10 contains a major arthritis gene and regulates disease severity, pannus formation, and joint damage
    • Brenner M., Meng H., Yarlett N., Griffiths M., Remmers E., Wilder R., Gulko P. The non-MHC quantitative trait locus Cia10 contains a major arthritis gene and regulates disease severity, pannus formation, and joint damage. Arthritis Rheum. 2005, 52(1):322-332.
    • (2005) Arthritis Rheum. , vol.52 , Issue.1 , pp. 322-332
    • Brenner, M.1    Meng, H.2    Yarlett, N.3    Griffiths, M.4    Remmers, E.5    Wilder, R.6    Gulko, P.7
  • 20
    • 46749129338 scopus 로고    scopus 로고
    • TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons
    • Qin N., Neeper M.P., Liu Y., Hutchinson T.L., Lubin M.L., Flores C.M. TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons. J. Neurosci. 2008, 28(24):6231-6238.
    • (2008) J. Neurosci. , vol.28 , Issue.24 , pp. 6231-6238
    • Qin, N.1    Neeper, M.P.2    Liu, Y.3    Hutchinson, T.L.4    Lubin, M.L.5    Flores, C.M.6
  • 22
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25(4):402-408.
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 23
    • 80155144555 scopus 로고    scopus 로고
    • CXCL10 and its receptor CXCR3 regulate synovial fibroblast invasion in rheumatoid arthritis
    • Laragione T., Brenner M., Sherry B., Gulko P.S. CXCL10 and its receptor CXCR3 regulate synovial fibroblast invasion in rheumatoid arthritis. Arthritis Rheum. 2011, 63(11):3274-3283.
    • (2011) Arthritis Rheum. , vol.63 , Issue.11 , pp. 3274-3283
    • Laragione, T.1    Brenner, M.2    Sherry, B.3    Gulko, P.S.4
  • 24
    • 34547478166 scopus 로고    scopus 로고
    • The GTPase Rac regulates the proliferation and invasion of fibroblast-like synoviocytes from rheumatoid arthritis patients
    • Chan A., Akhtar M., Brenner M., Zheng Y., Gulko P.S., Symons M. The GTPase Rac regulates the proliferation and invasion of fibroblast-like synoviocytes from rheumatoid arthritis patients. Mol. Med. 2007, 13(5-6):297-304.
    • (2007) Mol. Med. , vol.13 , Issue.5-6 , pp. 297-304
    • Chan, A.1    Akhtar, M.2    Brenner, M.3    Zheng, Y.4    Gulko, P.S.5    Symons, M.6
  • 27
    • 0018830639 scopus 로고
    • Immunisation against heterologous type II collagen induces arthritis in mice
    • Courtenay J.S., Dallman M.J., Dayan A.D., Martin A., Mosedale B. Immunisation against heterologous type II collagen induces arthritis in mice. Nature 1980, 283(5748):666-668.
    • (1980) Nature , vol.283 , Issue.5748 , pp. 666-668
    • Courtenay, J.S.1    Dallman, M.J.2    Dayan, A.D.3    Martin, A.4    Mosedale, B.5
  • 29
    • 20444426895 scopus 로고    scopus 로고
    • The non-MHC quantitative trait locus Cia5 contains three major arthritis genes that differentially regulate disease severity, pannus formation, and joint damage in collagen- and pristane-induced arthritis
    • Brenner M., Meng H.C., Yarlett N.C., Joe B., Griffiths M.M., Remmers E.F., Wilder R.L., Gulko P.S. The non-MHC quantitative trait locus Cia5 contains three major arthritis genes that differentially regulate disease severity, pannus formation, and joint damage in collagen- and pristane-induced arthritis. J. Immunol. 2005, 174(12):7894-7903.
    • (2005) J. Immunol. , vol.174 , Issue.12 , pp. 7894-7903
    • Brenner, M.1    Meng, H.C.2    Yarlett, N.C.3    Joe, B.4    Griffiths, M.M.5    Remmers, E.F.6    Wilder, R.L.7    Gulko, P.S.8
  • 30
    • 78650048949 scopus 로고    scopus 로고
    • Involvement of TRPV2 activation in intestinal movement through nitric oxide production in mice
    • Mihara H., Boudaka A., Shibasaki K., Yamanaka A., Sugiyama T., Tominaga M. Involvement of TRPV2 activation in intestinal movement through nitric oxide production in mice. J. Neurosci. 2010, 30(49):16536-16544.
    • (2010) J. Neurosci. , vol.30 , Issue.49 , pp. 16536-16544
    • Mihara, H.1    Boudaka, A.2    Shibasaki, K.3    Yamanaka, A.4    Sugiyama, T.5    Tominaga, M.6
  • 31
    • 60549111210 scopus 로고    scopus 로고
    • Dominant-negative inhibition of Ca2+ influx via TRPV2 ameliorates muscular dystrophy in animal models
    • Iwata Y., Katanosaka Y., Arai Y., Shigekawa M., Wakabayashi S. Dominant-negative inhibition of Ca2+ influx via TRPV2 ameliorates muscular dystrophy in animal models. Hum. Mol. Genet. 2009, 18(5):824-834.
    • (2009) Hum. Mol. Genet. , vol.18 , Issue.5 , pp. 824-834
    • Iwata, Y.1    Katanosaka, Y.2    Arai, Y.3    Shigekawa, M.4    Wakabayashi, S.5
  • 35
    • 40049093945 scopus 로고    scopus 로고
    • Blockade of chemokine receptor CXCR3 inhibits T cell recruitment to inflamed joints and decreases the severity of adjuvant arthritis
    • Mohan K., Issekutz T.B. Blockade of chemokine receptor CXCR3 inhibits T cell recruitment to inflamed joints and decreases the severity of adjuvant arthritis. J. Immunol. 2007, 179(12):8463-8469.
    • (2007) J. Immunol. , vol.179 , Issue.12 , pp. 8463-8469
    • Mohan, K.1    Issekutz, T.B.2
  • 36
    • 77955351696 scopus 로고    scopus 로고
    • Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis
    • Cejka D., Hayer S., Niederreiter B., Sieghart W., Fuereder T., Zwerina J., Schett G. Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis. Arthritis Rheum. 2010, 62(8):2294-2302.
    • (2010) Arthritis Rheum. , vol.62 , Issue.8 , pp. 2294-2302
    • Cejka, D.1    Hayer, S.2    Niederreiter, B.3    Sieghart, W.4    Fuereder, T.5    Zwerina, J.6    Schett, G.7
  • 37
    • 47949110435 scopus 로고    scopus 로고
    • Everolimus in patients with rheumatoid arthritis receiving concomitant methotrexate: a 3-month, double-blind, randomised, placebo-controlled, parallel-group, proof-of-concept study
    • Bruyn G.A., Tate G., Caeiro F., Maldonado-Cocco J., Westhovens R., Tannenbaum H., Bell M., Forre O., Bjorneboe O., Tak P.P., et al. Everolimus in patients with rheumatoid arthritis receiving concomitant methotrexate: a 3-month, double-blind, randomised, placebo-controlled, parallel-group, proof-of-concept study. Ann. Rheum. Dis. 2008, 67(8):1090-1095.
    • (2008) Ann. Rheum. Dis. , vol.67 , Issue.8 , pp. 1090-1095
    • Bruyn, G.A.1    Tate, G.2    Caeiro, F.3    Maldonado-Cocco, J.4    Westhovens, R.5    Tannenbaum, H.6    Bell, M.7    Forre, O.8    Bjorneboe, O.9    Tak, P.P.10
  • 38
    • 84861816840 scopus 로고    scopus 로고
    • A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis
    • Yellin M., Paliienko I., Balanescu A., Ter-Vartanian S., Tseluyko V., Xu L.A., Tao X., Cardarelli P.M., Leblanc H., Nichol G., et al. A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis. Arthritis Rheum. 2012, 64(6):1730-1739.
    • (2012) Arthritis Rheum. , vol.64 , Issue.6 , pp. 1730-1739
    • Yellin, M.1    Paliienko, I.2    Balanescu, A.3    Ter-Vartanian, S.4    Tseluyko, V.5    Xu, L.A.6    Tao, X.7    Cardarelli, P.M.8    Leblanc, H.9    Nichol, G.10
  • 39
    • 77954428063 scopus 로고    scopus 로고
    • ROS-NFkappaB mediates TGF-beta1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion
    • Tobar N., Villar V., Santibanez J.F. ROS-NFkappaB mediates TGF-beta1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion. Mol. Cell. Biochem. 2010, 340(1-2):195-202.
    • (2010) Mol. Cell. Biochem. , vol.340 , Issue.1-2 , pp. 195-202
    • Tobar, N.1    Villar, V.2    Santibanez, J.F.3
  • 41
    • 34247468418 scopus 로고    scopus 로고
    • IL-6 induces AGS gastric cancer cell invasion via activation of the c-Src/RhoA/ROCK signaling pathway
    • Lin M.T., Lin B.R., Chang C.C., Chu C.Y., Su H.J., Chen S.T., Jeng Y.M., Kuo M.L. IL-6 induces AGS gastric cancer cell invasion via activation of the c-Src/RhoA/ROCK signaling pathway. Int. J. Cancer 2007, 120(12):2600-2608.
    • (2007) Int. J. Cancer , vol.120 , Issue.12 , pp. 2600-2608
    • Lin, M.T.1    Lin, B.R.2    Chang, C.C.3    Chu, C.Y.4    Su, H.J.5    Chen, S.T.6    Jeng, Y.M.7    Kuo, M.L.8
  • 42
    • 80053451803 scopus 로고    scopus 로고
    • STAT3 knockdown reduces pancreatic cancer cell invasiveness and matrix metalloproteinase-7 expression in nude mice
    • (e25941)
    • Li H., Huang C., Huang K., Wu W., Jiang T., Cao J., Feng Z., Qiu Z. STAT3 knockdown reduces pancreatic cancer cell invasiveness and matrix metalloproteinase-7 expression in nude mice. PLoS ONE 2011, 6(10). (e25941).
    • (2011) PLoS ONE , vol.6 , Issue.10
    • Li, H.1    Huang, C.2    Huang, K.3    Wu, W.4    Jiang, T.5    Cao, J.6    Feng, Z.7    Qiu, Z.8
  • 43
    • 0035003212 scopus 로고    scopus 로고
    • Regulation of the cytoskeleton by Rho-family GTPases: implications for tumour cell invasion
    • Price L.S., Collard J.G. Regulation of the cytoskeleton by Rho-family GTPases: implications for tumour cell invasion. Semin. Cancer Biol. 2001, 11(2):167-173.
    • (2001) Semin. Cancer Biol. , vol.11 , Issue.2 , pp. 167-173
    • Price, L.S.1    Collard, J.G.2
  • 44
    • 79958772180 scopus 로고    scopus 로고
    • Cdc42 in oncogenic transformation, invasion, and tumorigenesis
    • Stengel K., Zheng Y. Cdc42 in oncogenic transformation, invasion, and tumorigenesis. Cell. Signal. 2011, 23(9):1415-1423.
    • (2011) Cell. Signal. , vol.23 , Issue.9 , pp. 1415-1423
    • Stengel, K.1    Zheng, Y.2
  • 45
    • 78651359424 scopus 로고    scopus 로고
    • Invasion of breast cancer cells into collagen matrix requires TGF-alpha and Cdc42 signaling
    • Kikuchi K., Li X., Zheng Y., Takano Y. Invasion of breast cancer cells into collagen matrix requires TGF-alpha and Cdc42 signaling. FEBS Lett. 2011, 585(2):286-290.
    • (2011) FEBS Lett. , vol.585 , Issue.2 , pp. 286-290
    • Kikuchi, K.1    Li, X.2    Zheng, Y.3    Takano, Y.4
  • 46
    • 81855169565 scopus 로고    scopus 로고
    • Cancer invasion and the microenvironment: plasticity and reciprocity
    • Friedl P., Alexander S. Cancer invasion and the microenvironment: plasticity and reciprocity. Cell 2011, 147(5):992-1009.
    • (2011) Cell , vol.147 , Issue.5 , pp. 992-1009
    • Friedl, P.1    Alexander, S.2
  • 47
    • 35348847256 scopus 로고    scopus 로고
    • Transforming growth factor-beta signaling in cancer invasion and metastasis
    • Leivonen S.K., Kahari V.M. Transforming growth factor-beta signaling in cancer invasion and metastasis. Int. J. Cancer 2007, 121(10):2119-2124.
    • (2007) Int. J. Cancer , vol.121 , Issue.10 , pp. 2119-2124
    • Leivonen, S.K.1    Kahari, V.M.2


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