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Volumn 23, Issue 5, 2015, Pages 919-926

Progress in the molecular understanding of central regulation of body weight by estrogens

Author keywords

[No Author keywords available]

Indexed keywords

AGOUTI RELATED PROTEIN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; G PROTEIN COUPLED RECEPTOR 30; NEUROPEPTIDE Y; PROOPIOMELANOCORTIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX2.1; UNCLASSIFIED DRUG; ESTROGEN; ESTROGEN RECEPTOR;

EID: 84928590877     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1002/oby.21099     Document Type: Review
Times cited : (27)

References (75)
  • 1
    • 58149110969 scopus 로고    scopus 로고
    • Women and the metabolic syndrome: An overview of its peculiarities
    • Allende-Vigo MZ,. Women and the metabolic syndrome: an overview of its peculiarities. P R Health Sci J 2008; 27: 190-195.
    • (2008) P R Health Sci J , vol.27 , pp. 190-195
    • Allende-Vigo, M.Z.1
  • 3
    • 84865151198 scopus 로고    scopus 로고
    • Central versus peripheral impact of estradiol on the impaired glucose metabolism in ovariectomized mice on a high-fat diet
    • Yonezawa R, Wada T, Matsumoto N, et al. Central versus peripheral impact of estradiol on the impaired glucose metabolism in ovariectomized mice on a high-fat diet. Am J Physiol Endocrinol Metab 2012; 303: E445-E456.
    • (2012) Am J Physiol Endocrinol Metab , vol.303 , pp. E445-E456
    • Yonezawa, R.1    Wada, T.2    Matsumoto, N.3
  • 4
    • 84878632677 scopus 로고    scopus 로고
    • The role of estrogens in control of energy balance and glucose homeostasis
    • Mauvais-Jarvis F, Clegg DJ, Hevener AL,. The role of estrogens in control of energy balance and glucose homeostasis. Endocr Rev 2013; 34: 309-338.
    • (2013) Endocr Rev , vol.34 , pp. 309-338
    • Mauvais-Jarvis, F.1    Clegg, D.J.2    Hevener, A.L.3
  • 5
    • 0017189871 scopus 로고
    • Ovarian influences on the meal patterns of female rats
    • Blaustein JD, Wade GN,. Ovarian influences on the meal patterns of female rats. Physiol Behav 1976; 17: 201-208.
    • (1976) Physiol Behav , vol.17 , pp. 201-208
    • Blaustein, J.D.1    Wade, G.N.2
  • 6
    • 0015821522 scopus 로고
    • Sexual behaviour and sexual motivation in the female rat
    • Drewett RF,. Sexual behaviour and sexual motivation in the female rat. Nature 1973; 242: 476-477.
    • (1973) Nature , vol.242 , pp. 476-477
    • Drewett, R.F.1
  • 7
    • 0034751475 scopus 로고    scopus 로고
    • Deficits in E2-dependent control of feeding, weight gain, and cholecystokinin satiation in ER-alpha null mice
    • Geary N, Asarian L, Korach KS, Pfaff DW, Ogawa S,. Deficits in E2-dependent control of feeding, weight gain, and cholecystokinin satiation in ER-alpha null mice. Endocrinology 2001; 142: 4751-4577.
    • (2001) Endocrinology , vol.142 , pp. 4751-4577
    • Geary, N.1    Asarian, L.2    Korach, K.S.3    Pfaff, D.W.4    Ogawa, S.5
  • 8
    • 0034843320 scopus 로고    scopus 로고
    • Sex hormones and the selective estrogen receptor modulator tamoxifen modulate weekly body weights and food intakes in adolescent and adult rats
    • Wallen WJ, Belanger MP, Wittnich C,. Sex hormones and the selective estrogen receptor modulator tamoxifen modulate weekly body weights and food intakes in adolescent and adult rats. J Nutr 2001; 131: 2351-2357.
    • (2001) J Nutr , vol.131 , pp. 2351-2357
    • Wallen, W.J.1    Belanger, M.P.2    Wittnich, C.3
  • 9
    • 29144482697 scopus 로고    scopus 로고
    • Effects of selective estrogen receptor agonists on food intake and body weight gain in rats
    • Roesch DM,. Effects of selective estrogen receptor agonists on food intake and body weight gain in rats. Physiol Behav 2006; 87: 39-44.
    • (2006) Physiol Behav , vol.87 , pp. 39-44
    • Roesch, D.M.1
  • 10
    • 66449086930 scopus 로고    scopus 로고
    • Reduced energy expenditure and increased inflammation are early events in the development of ovariectomy-induced obesity
    • Rogers NH, Perfield JW, II, Strissel KJ, Obin MS, Greenberg AS,. Reduced energy expenditure and increased inflammation are early events in the development of ovariectomy-induced obesity. Endocrinology 2009; 150: 2161-2168.
    • (2009) Endocrinology , vol.150 , pp. 2161-2168
    • Rogers, N.H.1    Perfield, I.I.J.W.2    Strissel, K.J.3    Obin, M.S.4    Greenberg, A.S.5
  • 11
    • 0041317787 scopus 로고    scopus 로고
    • Association of polymorphisms in the estrogen receptor alpha gene with body fat distribution
    • Okura T, Koda M, Ando F, Niino N, Ohta S, Shimokata H,. Association of polymorphisms in the estrogen receptor alpha gene with body fat distribution. Int J Obes Relat Metab Disord 2003; 27: 1020-1027.
    • (2003) Int J Obes Relat Metab Disord , vol.27 , pp. 1020-1027
    • Okura, T.1    Koda, M.2    Ando, F.3    Niino, N.4    Ohta, S.5    Shimokata, H.6
  • 13
    • 0024341556 scopus 로고
    • Central implants of diluted estradiol: Independent effects on ingestive and reproductive behaviors of ovariectomized rats
    • Butera PC, Beikirch RJ,. Central implants of diluted estradiol: independent effects on ingestive and reproductive behaviors of ovariectomized rats. Brain Res 1989; 491: 266-273.
    • (1989) Brain Res , vol.491 , pp. 266-273
    • Butera, P.C.1    Beikirch, R.J.2
  • 14
    • 0022572330 scopus 로고
    • Peripheral effects of estrogen on food intake and lipoprotein lipase activity in ovariectomized rats
    • Palmer K, Gray JM,., Central vs,. peripheral effects of estrogen on food intake and lipoprotein lipase activity in ovariectomized rats. Physiol Behav 1986; 37: 187-189.
    • (1986) Physiol Behav , vol.37 , pp. 187-189
    • Palmer, K.1    Gray, J.M.2    Central, V.3
  • 15
    • 35548936522 scopus 로고    scopus 로고
    • Estrogen receptor-alpha expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice
    • Feng Y, Manka D, Wagner KU, Khan SA,. Estrogen receptor-alpha expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice. Proc Natl Acad Sci USA 2007; 104: 14718-14723.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 14718-14723
    • Feng, Y.1    Manka, D.2    Wagner, K.U.3    Khan, S.A.4
  • 16
    • 0034703229 scopus 로고    scopus 로고
    • Role of brain insulin receptor in control of body weight and reproduction
    • Bruning JC, Gautam D, Burks DJ, et al. Role of brain insulin receptor in control of body weight and reproduction. Science 2000; 289: 2122-2125.
    • (2000) Science , vol.289 , pp. 2122-2125
    • Bruning, J.C.1    Gautam, D.2    Burks, D.J.3
  • 17
    • 80053899725 scopus 로고    scopus 로고
    • Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction
    • Xu Y, Nedungadi TP, Zhu L, et al. Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction. Cell Metab 2011; 14: 453-465.
    • (2011) Cell Metab , vol.14 , pp. 453-465
    • Xu, Y.1    Nedungadi, T.P.2    Zhu, L.3
  • 18
    • 2342584831 scopus 로고    scopus 로고
    • Distribution of estrogen receptor alpha and beta in the mouse central nervous system: In vivo autoradiographic and immunocytochemical analyses
    • Merchenthaler I, Lane MV, Numan S, Dellovade TL,. Distribution of estrogen receptor alpha and beta in the mouse central nervous system: in vivo autoradiographic and immunocytochemical analyses. J Comp Neurol 2004; 473: 270-291.
    • (2004) J Comp Neurol , vol.473 , pp. 270-291
    • Merchenthaler, I.1    Lane, M.V.2    Numan, S.3    Dellovade, T.L.4
  • 19
    • 31944452253 scopus 로고    scopus 로고
    • The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight
    • King BM,. The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight. Physiol Behav 2006; 87: 221-244.
    • (2006) Physiol Behav , vol.87 , pp. 221-244
    • King, B.M.1
  • 20
    • 33847793319 scopus 로고    scopus 로고
    • Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome
    • Musatov S, Chen W, Pfaff DW, et al. Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome. Proc Natl Acad Sci USA 2007; 104: 2501-2506.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 2501-2506
    • Musatov, S.1    Chen, W.2    Pfaff, D.W.3
  • 21
    • 30644473109 scopus 로고    scopus 로고
    • Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis
    • Dhillon H, Zigman JM, Ye C, et al. Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron 2006; 49: 191-203.
    • (2006) Neuron , vol.49 , pp. 191-203
    • Dhillon, H.1    Zigman, J.M.2    Ye, C.3
  • 22
    • 84904043360 scopus 로고    scopus 로고
    • Estradiol regulates brown adipose tissue thermogenesis via hypothalamic AMPK
    • Martinez de Morentin PB, Gonzalez-Garcia I, Martins L, et al. Estradiol regulates brown adipose tissue thermogenesis via hypothalamic AMPK. Cell Metab 2014; 20: 41-53.
    • (2014) Cell Metab , vol.20 , pp. 41-53
    • Martinez De Morentin, P.B.1    Gonzalez-Garcia, I.2    Martins, L.3
  • 23
    • 84920773970 scopus 로고    scopus 로고
    • An estrogen-responsive module in the ventromedial hypothalamus selectively drives sex-specific activity in females
    • Correa SM, Newstrom DW, Warne JP, et al. An estrogen-responsive module in the ventromedial hypothalamus selectively drives sex-specific activity in females. Cell Rep 2015; 10: 62-74.
    • (2015) Cell Rep , vol.10 , pp. 62-74
    • Correa, S.M.1    Newstrom, D.W.2    Warne, J.P.3
  • 24
    • 0033082380 scopus 로고    scopus 로고
    • From lesions to leptin: Hypothalamic control of food intake and body weight
    • Elmquist JK, Elias CF, Saper CB,. From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 1999; 22: 221-232.
    • (1999) Neuron , vol.22 , pp. 221-232
    • Elmquist, J.K.1    Elias, C.F.2    Saper, C.B.3
  • 25
    • 17844401704 scopus 로고    scopus 로고
    • Anatomy and regulation of the central melanocortin system
    • Cone RD,. Anatomy and regulation of the central melanocortin system. Nat Neurosci 2005; 8: 571-578.
    • (2005) Nat Neurosci , vol.8 , pp. 571-578
    • Cone, R.D.1
  • 26
    • 21044454460 scopus 로고    scopus 로고
    • The melanocortin system as a central integrator of direct and indirect controls of food intake
    • Williams DL, Schwartz MW,. The melanocortin system as a central integrator of direct and indirect controls of food intake. Am J Physiol Regul Integr Comp Physiol 2005; 289: R2-R3.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.289 , pp. R2-R3
    • Williams, D.L.1    Schwartz, M.W.2
  • 27
    • 0032772960 scopus 로고    scopus 로고
    • The central melanocortin system and energy homeostasis
    • Cone RD,. The central melanocortin system and energy homeostasis. Trends Endocrinol Metab 1999; 10: 211-216.
    • (1999) Trends Endocrinol Metab , vol.10 , pp. 211-216
    • Cone, R.D.1
  • 28
    • 0030889192 scopus 로고    scopus 로고
    • Targeted disruption of the melanocortin-4 receptor results in obesity in mice
    • Huszar D, Lynch CA, Fairchild-Huntress V, et al. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 1997; 88: 131-141.
    • (1997) Cell , vol.88 , pp. 131-141
    • Huszar, D.1    Lynch, C.A.2    Fairchild-Huntress, V.3
  • 29
    • 70349452304 scopus 로고    scopus 로고
    • Functional requirement of AgRP and NPY neurons in ovarian cycle-dependent regulation of food intake
    • Olofsson LE, Pierce AA, Xu AW,. Functional requirement of AgRP and NPY neurons in ovarian cycle-dependent regulation of food intake. Proc Natl Acad Sci USA 2009; 106: 15932-15937.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 15932-15937
    • Olofsson, L.E.1    Pierce, A.A.2    Xu, A.W.3
  • 30
    • 0029026771 scopus 로고
    • Effects of age and long-term ovariectomy on the estrogen-receptor containing subpopulations of beta-endorphin-immunoreactive neurons in the arcuate nucleus of female C57BL/6J mice
    • Miller MM, Tousignant P, Yang U, Pedvis S, Billiar RB,. Effects of age and long-term ovariectomy on the estrogen-receptor containing subpopulations of beta-endorphin-immunoreactive neurons in the arcuate nucleus of female C57BL/6J mice. Neuroendocrinology 1995; 61: 542-551.
    • (1995) Neuroendocrinology , vol.61 , pp. 542-551
    • Miller, M.M.1    Tousignant, P.2    Yang, U.3    Pedvis, S.4    Billiar, R.B.5
  • 31
    • 79955934209 scopus 로고    scopus 로고
    • The estrogen receptor alpha colocalizes with proopiomelanocortin in hypothalamic neurons and binds to a conserved motif present in the neuron-specific enhancer nPE2
    • de Souza FS, Nasif S, Lopez-Leal R, Levi DH, Low MJ, Rubinsten M,. The estrogen receptor alpha colocalizes with proopiomelanocortin in hypothalamic neurons and binds to a conserved motif present in the neuron-specific enhancer nPE2. Eur J Pharmacol 2011; 660: 181-187.
    • (2011) Eur J Pharmacol , vol.660 , pp. 181-187
    • De Souza, F.S.1    Nasif, S.2    Lopez-Leal, R.3    Levi, D.H.4    Low, M.J.5    Rubinsten, M.6
  • 32
    • 33846046623 scopus 로고    scopus 로고
    • Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals
    • Gao Q, Mezei G, Nie Y, et al. Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals. Nat Med 2007; 13: 89-94.
    • (2007) Nat Med , vol.13 , pp. 89-94
    • Gao, Q.1    Mezei, G.2    Nie, Y.3
  • 34
    • 2942733252 scopus 로고    scopus 로고
    • Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis
    • Balthasar N, Coppari R, McMinn J, et al. Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis. Neuron 2004; 42: 983-991.
    • (2004) Neuron , vol.42 , pp. 983-991
    • Balthasar, N.1    Coppari, R.2    McMinn, J.3
  • 35
    • 84907495482 scopus 로고    scopus 로고
    • Estrogens stimulate serotonin neurons to inhibit binge-like eating in mice
    • Cao X, Xu P, Oyola MG, et al. Estrogens stimulate serotonin neurons to inhibit binge-like eating in mice. J Clin Invest 2014; 124: 4351-4362.
    • (2014) J Clin Invest , vol.124 , pp. 4351-4362
    • Cao, X.1    Xu, P.2    Oyola, M.G.3
  • 36
    • 79959837740 scopus 로고    scopus 로고
    • Serotonergic system involvement in the inhibitory action of estrogen on induced sodium appetite in female rats
    • Dalmasso C, Amigone JL, Vivas L,. Serotonergic system involvement in the inhibitory action of estrogen on induced sodium appetite in female rats. Physiol Behav 2011; 104: 398-407.
    • (2011) Physiol Behav , vol.104 , pp. 398-407
    • Dalmasso, C.1    Amigone, J.L.2    Vivas, L.3
  • 37
    • 17544365103 scopus 로고    scopus 로고
    • Oestrogen and testosterone modulate the firing activity of dorsal raphe nucleus serotonergic neurones in both male and female rats
    • Robichaud M, Debonnel G,. Oestrogen and testosterone modulate the firing activity of dorsal raphe nucleus serotonergic neurones in both male and female rats. J Neuroendocrinol 2005; 17: 179-185.
    • (2005) J Neuroendocrinol , vol.17 , pp. 179-185
    • Robichaud, M.1    Debonnel, G.2
  • 38
    • 79958072418 scopus 로고    scopus 로고
    • Estradiol acts in the medial preoptic area, arcuate nucleus, and dorsal raphe nucleus to reduce food intake in ovariectomized rats
    • Santollo J, Torregrossa AM, Eckel LA,. Estradiol acts in the medial preoptic area, arcuate nucleus, and dorsal raphe nucleus to reduce food intake in ovariectomized rats. Horm Behav 2011; 60: 86-93.
    • (2011) Horm Behav , vol.60 , pp. 86-93
    • Santollo, J.1    Torregrossa, A.M.2    Eckel, L.A.3
  • 39
    • 36349004794 scopus 로고    scopus 로고
    • Estradiol enhances cholecystokinin-dependent lipid-induced satiation and activates estrogen receptor-alpha-expressing cells in the nucleus tractus solitarius of ovariectomized rats
    • Asarian L, Geary N,. Estradiol enhances cholecystokinin-dependent lipid-induced satiation and activates estrogen receptor-alpha-expressing cells in the nucleus tractus solitarius of ovariectomized rats. Endocrinology 2007; 148: 5656-5666.
    • (2007) Endocrinology , vol.148 , pp. 5656-5666
    • Asarian, L.1    Geary, N.2
  • 40
    • 41549130400 scopus 로고    scopus 로고
    • Hindbrain administration of estradiol inhibits feeding and activates estrogen receptor-alpha-expressing cells in the nucleus tractus solitarius of ovariectomized rats
    • Thammacharoen S, Lutz TA, Geary N, Asarian L,. Hindbrain administration of estradiol inhibits feeding and activates estrogen receptor-alpha-expressing cells in the nucleus tractus solitarius of ovariectomized rats. Endocrinology 2008; 149: 1609-1617.
    • (2008) Endocrinology , vol.149 , pp. 1609-1617
    • Thammacharoen, S.1    Lutz, T.A.2    Geary, N.3    Asarian, L.4
  • 41
    • 2342584831 scopus 로고    scopus 로고
    • Distribution of estrogen receptor alpha and beta in the mouse central nervous system: In vivo autoradiographic and immunocytochemical analyses
    • Merchenthaler I, Lane MV, Numan S, Dellovade TL,. Distribution of estrogen receptor alpha and beta in the mouse central nervous system: in vivo autoradiographic and immunocytochemical analyses. J Comp Neurol 2004; 473: 270-291.
    • (2004) J Comp Neurol , vol.473 , pp. 270-291
    • Merchenthaler, I.1    Lane, M.V.2    Numan, S.3    Dellovade, T.L.4
  • 42
    • 0019796287 scopus 로고
    • Modulation of food intake by amygdaloid estradiol benzoate implants in female rats
    • Donohoe TP, Stevens R,. Modulation of food intake by amygdaloid estradiol benzoate implants in female rats. Physiol Behav 1981; 27: 105-114.
    • (1981) Physiol Behav , vol.27 , pp. 105-114
    • Donohoe, T.P.1    Stevens, R.2
  • 44
    • 58249110407 scopus 로고    scopus 로고
    • Differential regulation of bone and body composition in male mice with combined inactivation of androgen and estrogen receptor-alpha
    • Callewaert F, Venken K, Ophoff J, et al. Differential regulation of bone and body composition in male mice with combined inactivation of androgen and estrogen receptor-alpha. FASEB J 2009; 23: 232-240.
    • (2009) FASEB J , vol.23 , pp. 232-240
    • Callewaert, F.1    Venken, K.2    Ophoff, J.3
  • 45
    • 0033305733 scopus 로고    scopus 로고
    • Estrogen: Consequences and implications of human mutations in synthesis and action
    • Grumbach MM, Auchus RJ,. Estrogen: consequences and implications of human mutations in synthesis and action. J Clin Endocrinol Metab 1999; 84: 4677-4694.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 4677-4694
    • Grumbach, M.M.1    Auchus, R.J.2
  • 46
    • 0028143234 scopus 로고
    • Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man
    • Smith EP, Boyd J, Frank GR, et al. Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. N Engl J Med 1994; 331: 1056-1061.
    • (1994) N Engl J Med , vol.331 , pp. 1056-1061
    • Smith, E.P.1    Boyd, J.2    Frank, G.R.3
  • 47
    • 84870902173 scopus 로고    scopus 로고
    • Targeted estrogen delivery reverses the metabolic syndrome
    • Finan B, Yang B, Ottaway N, et al. Targeted estrogen delivery reverses the metabolic syndrome. Nat Med 2012; 18: 1847-1856.
    • (2012) Nat Med , vol.18 , pp. 1847-1856
    • Finan, B.1    Yang, B.2    Ottaway, N.3
  • 48
    • 12944276957 scopus 로고    scopus 로고
    • Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity
    • Jones ME, Thorburn AW, Britt KL, et al. Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity. Proc Natl Acad Sci USA 2000; 97: 12735-12740.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12735-12740
    • Jones, M.E.1    Thorburn, A.W.2    Britt, K.L.3
  • 49
    • 70349456163 scopus 로고    scopus 로고
    • Estrogen masculinizes neural pathways and sex-specific behaviors
    • Wu MV, Manoli DS, Fraser EJ, et al. Estrogen masculinizes neural pathways and sex-specific behaviors. Cell 2009; 139: 61-72.
    • (2009) Cell , vol.139 , pp. 61-72
    • Wu, M.V.1    Manoli, D.S.2    Fraser, E.J.3
  • 50
    • 79551532122 scopus 로고    scopus 로고
    • Genetic rescue of nonclassical ERalpha signaling normalizes energy balance in obese Eralpha-null mutant mice
    • Park CJ, Zhao Z, Glidewell-Kenney C, et al. Genetic rescue of nonclassical ERalpha signaling normalizes energy balance in obese Eralpha-null mutant mice. J Clin Invest 2011; 121: 604-612.
    • (2011) J Clin Invest , vol.121 , pp. 604-612
    • Park, C.J.1    Zhao, Z.2    Glidewell-Kenney, C.3
  • 51
    • 63649148223 scopus 로고    scopus 로고
    • Developmental phenotype of a membrane only estrogen receptor alpha (MOER) mouse
    • Pedram A, Razandi M, Kim JK, et al. Developmental phenotype of a membrane only estrogen receptor alpha (MOER) mouse. J Biol Chem 2009; 284: 3488-3495.
    • (2009) J Biol Chem , vol.284 , pp. 3488-3495
    • Pedram, A.1    Razandi, M.2    Kim, J.K.3
  • 52
    • 0036795423 scopus 로고    scopus 로고
    • An estrogen receptor (ER)alpha deoxyribonucleic acid-binding domain knock-in mutation provides evidence for nonclassical ER pathway signaling in vivo
    • Jakacka M, Ito M, Martinson F, Ishikawa T, Lee EJ, Jameson JL,. An estrogen receptor (ER)alpha deoxyribonucleic acid-binding domain knock-in mutation provides evidence for nonclassical ER pathway signaling in vivo. Mol Endocrinol 2002; 16: 2188-2201.
    • (2002) Mol Endocrinol , vol.16 , pp. 2188-2201
    • Jakacka, M.1    Ito, M.2    Martinson, F.3    Ishikawa, T.4    Lee, E.J.5    Jameson, J.L.6
  • 53
    • 84871683410 scopus 로고    scopus 로고
    • Steroid receptor coactivator-1 mediates estrogenic actions to prevent body weight gain in female mice
    • Zhu L, Yang Y, Xu P, et al. Steroid receptor coactivator-1 mediates estrogenic actions to prevent body weight gain in female mice. Endocrinology 2013; 154: 150-158.
    • (2013) Endocrinology , vol.154 , pp. 150-158
    • Zhu, L.1    Yang, Y.2    Xu, P.3
  • 54
    • 0034735999 scopus 로고    scopus 로고
    • Obesity and disturbed lipoprotein profile in estrogen receptor-alpha-deficient male mice
    • Ohlsson C, Hellberg N, Parini P, et al. Obesity and disturbed lipoprotein profile in estrogen receptor-alpha-deficient male mice. Biochem Biophys Res Commun 2000; 278: 640-645.
    • (2000) Biochem Biophys Res Commun , vol.278 , pp. 640-645
    • Ohlsson, C.1    Hellberg, N.2    Parini, P.3
  • 55
    • 36849022711 scopus 로고    scopus 로고
    • Acute activation of ER alpha decreases food intake, meal size, and body weight in ovariectomized rats
    • Santollo J, Wiley MD, Eckel LA,. Acute activation of ER alpha decreases food intake, meal size, and body weight in ovariectomized rats. Am J Physiol Regul Integr Comp Physiol 2007; 293: R2194-R2201.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.293 , pp. R2194-R2201
    • Santollo, J.1    Wiley, M.D.2    Eckel, L.A.3
  • 56
    • 46249083607 scopus 로고    scopus 로고
    • Metabolic actions of estrogen receptor beta (ERbeta) are mediated by a negative cross-talk with PPARgamma
    • Foryst-Ludwig A, Clemenz M, Hohmann S, et al. Metabolic actions of estrogen receptor beta (ERbeta) are mediated by a negative cross-talk with PPARgamma. PLoS Genet 2008; 4: e1000108.
    • (2008) PLoS Genet , vol.4 , pp. e1000108
    • Foryst-Ludwig, A.1    Clemenz, M.2    Hohmann, S.3
  • 57
    • 77957768699 scopus 로고    scopus 로고
    • Estrogen receptor-{beta}-selective ligands alleviate high-fat diet- and ovariectomy-induced obesity in mice
    • Yepuru M, Eswaraka J, Kearbey JD, et al. Estrogen receptor-{beta}-selective ligands alleviate high-fat diet- and ovariectomy-induced obesity in mice. J Biol Chem 2010; 285: 31292-1303.
    • (2010) J Biol Chem , vol.285 , pp. 31292-31303
    • Yepuru, M.1    Eswaraka, J.2    Kearbey, J.D.3
  • 58
    • 61949405394 scopus 로고    scopus 로고
    • Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity
    • Haas E, Bhattacharya I, Brailoiu E, et al. Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity. Circ Res 2009; 104: 288-291.
    • (2009) Circ Res , vol.104 , pp. 288-291
    • Haas, E.1    Bhattacharya, I.2    Brailoiu, E.3
  • 59
    • 84886546730 scopus 로고    scopus 로고
    • GPER deficiency in male mice results in insulin resistance, dyslipidemia, and a proinflammatory state
    • Sharma G, Hu C, Brigman JL, Zhu G, Hathaway HJ, Prossnitz ER,. GPER deficiency in male mice results in insulin resistance, dyslipidemia, and a proinflammatory state. Endocrinology 2013; 154: 4136-4145.
    • (2013) Endocrinology , vol.154 , pp. 4136-4145
    • Sharma, G.1    Hu, C.2    Brigman, J.L.3    Zhu, G.4    Hathaway, H.J.5    Prossnitz, E.R.6
  • 60
    • 40849098707 scopus 로고    scopus 로고
    • GPR30 contributes to estrogen-induced thymic atrophy
    • Wang C, Dehghani B, Magrisso IJ, et al. GPR30 contributes to estrogen-induced thymic atrophy. Mol Endocrinol 2008; 22: 636-648.
    • (2008) Mol Endocrinol , vol.22 , pp. 636-648
    • Wang, C.1    Dehghani, B.2    Magrisso, I.J.3
  • 61
    • 70349649964 scopus 로고    scopus 로고
    • Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival
    • Liu S, Le May C, Wong WP, et al. Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival. Diabetes 2009; 58: 2292-2302.
    • (2009) Diabetes , vol.58 , pp. 2292-2302
    • Liu, S.1    Le May, C.2    Wong, W.P.3
  • 62
    • 58149512521 scopus 로고    scopus 로고
    • GPR30 does not mediate estrogenic responses in reproductive organs in mice
    • Otto C, Fuchs I, Kauselmann G, et al. GPR30 does not mediate estrogenic responses in reproductive organs in mice. Biol Reprod 2009; 80: 34-41.
    • (2009) Biol Reprod , vol.80 , pp. 34-41
    • Otto, C.1    Fuchs, I.2    Kauselmann, G.3
  • 63
    • 59649122739 scopus 로고    scopus 로고
    • Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice
    • Martensson UE, Salehi SA, Windahl S, et al. Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice. Endocrinology 2009; 150: 687-698.
    • (2009) Endocrinology , vol.150 , pp. 687-698
    • Martensson, U.E.1    Salehi, S.A.2    Windahl, S.3
  • 64
    • 84901836534 scopus 로고    scopus 로고
    • Sexually dimorphic role of G protein-coupled estrogen receptor (GPER) in modulating energy homeostasis
    • Davis KE, Carstens EJ, Irani BG, Gent LM, Hahner LM, Clegg DJ,. Sexually dimorphic role of G protein-coupled estrogen receptor (GPER) in modulating energy homeostasis. Horm Behav 2014; 66: 196-207.
    • (2014) Horm Behav , vol.66 , pp. 196-207
    • Davis, K.E.1    Carstens, E.J.2    Irani, B.G.3    Gent, L.M.4    Hahner, L.M.5    Clegg, D.J.6
  • 65
    • 84883240503 scopus 로고    scopus 로고
    • The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosis
    • Davis KE, M DN, Sun K, et al. The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosis. Mol Metab 2013; 2: 227-242.
    • (2013) Mol Metab , vol.2 , pp. 227-242
    • Davis, K.E.1    Sun, K.2
  • 66
    • 84873040492 scopus 로고    scopus 로고
    • Estrogen treatment after ovariectomy protects against fatty liver and may improve pathway-selective insulin resistance
    • Zhu L, Brown WC, Cai Q, et al. Estrogen treatment after ovariectomy protects against fatty liver and may improve pathway-selective insulin resistance. Diabetes 2013; 62: 424-434.
    • (2013) Diabetes , vol.62 , pp. 424-434
    • Zhu, L.1    Brown, W.C.2    Cai, Q.3
  • 67
    • 40649084350 scopus 로고    scopus 로고
    • Sterility and absence of histopathological defects in nonreproductive organs of a mouse ERbeta-null mutant
    • Antal MC, Krust A, Chambon P, Mark M,. Sterility and absence of histopathological defects in nonreproductive organs of a mouse ERbeta-null mutant. Proc Natl Acad Sci USA 2008; 105: 2433-2438.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 2433-2438
    • Antal, M.C.1    Krust, A.2    Chambon, P.3    Mark, M.4
  • 68
    • 84901660911 scopus 로고    scopus 로고
    • Scalable control of mounting and attack by Esr1 neurons in the ventromedial hypothalamus
    • Lee H, Kim DW, Remedios R, et al. Scalable control of mounting and attack by Esr1 neurons in the ventromedial hypothalamus. Nature 2014; 509: 627-632.
    • (2014) Nature , vol.509 , pp. 627-632
    • Lee, H.1    Kim, D.W.2    Remedios, R.3
  • 69
    • 84880333194 scopus 로고    scopus 로고
    • Visualisation and characterisation of oestrogen receptor alpha-positive neurons expressing green fluorescent protein under the control of the oestrogen receptor alpha promoter
    • Matsuda KI, Yanagisawa M, Sano K, et al. Visualisation and characterisation of oestrogen receptor alpha-positive neurons expressing green fluorescent protein under the control of the oestrogen receptor alpha promoter. Eur J Neurosci 2013; 38: 2242-2249.
    • (2013) Eur J Neurosci , vol.38 , pp. 2242-2249
    • Matsuda, K.I.1    Yanagisawa, M.2    Sano, K.3
  • 70
    • 77956175251 scopus 로고    scopus 로고
    • Distribution of estrogen receptor beta containing cells in the brains of bacterial artificial chromosome transgenic mice
    • Milner TA, Thompson LI, Wang G, et al. Distribution of estrogen receptor beta containing cells in the brains of bacterial artificial chromosome transgenic mice. Brain Res 2010; 1351: 74-96.
    • (2010) Brain Res , vol.1351 , pp. 74-96
    • Milner, T.A.1    Thompson, L.I.2    Wang, G.3
  • 71
    • 84861976352 scopus 로고    scopus 로고
    • FoxO1 target Gpr17 activates AgRP neurons to regulate food intake
    • Ren H, Orozco IJ, Su Y, et al. FoxO1 target Gpr17 activates AgRP neurons to regulate food intake. Cell 2012; 149: 1314-1326.
    • (2012) Cell , vol.149 , pp. 1314-1326
    • Ren, H.1    Orozco, I.J.2    Su, Y.3
  • 72
    • 84895796518 scopus 로고    scopus 로고
    • Tissue-selective estrogen complexes with bazedoxifene prevent metabolic dysfunction in female mice
    • Kim JH, Meyers MS, Khuder SS, et al. Tissue-selective estrogen complexes with bazedoxifene prevent metabolic dysfunction in female mice. Mol Metab 2014; 3: 177-190.
    • (2014) Mol Metab , vol.3 , pp. 177-190
    • Kim, J.H.1    Meyers, M.S.2    Khuder, S.S.3
  • 74
    • 80155159963 scopus 로고    scopus 로고
    • Bazedoxifene: A review of its use in the treatment of postmenopausal osteoporosis
    • Duggan ST, McKeage K,. Bazedoxifene: a review of its use in the treatment of postmenopausal osteoporosis. Drugs 2011; 71: 2193-2212.
    • (2011) Drugs , vol.71 , pp. 2193-2212
    • Duggan, S.T.1    McKeage, K.2
  • 75
    • 84875072876 scopus 로고    scopus 로고
    • The interactive effects of estrogen and progesterone on changes in emotional eating across the menstrual cycle
    • Klump KL, Keel PK, Racine SE, et al. The interactive effects of estrogen and progesterone on changes in emotional eating across the menstrual cycle. J Abnorm Psychol 2013; 122: 131-137.
    • (2013) J Abnorm Psychol , vol.122 , pp. 131-137
    • Klump, K.L.1    Keel, P.K.2    Racine, S.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.