Usefulness of colchicine to reduce perioperative myocardial damage in patients who underwent on-pump coronary artery bypass grafting

American Journal of Cardiology

Volumn 115, Issue 10, 2015, Pages 1376-1381

  Giannopoulos, Georgios ^a,b   Angelidis, Christos ^a   Kouritas, Vasileios K ^c   Dedeilias, Panagiotis ^c   Filippatos, Gerasimos ^d   Cleman, Michael W ^b   Panagopoulou, Vasiliki ^d   Siasos, Gerasimos ^d   Tousoulis, Dimitrios ^d   Lekakis, John ^d   Deftereos, Spyridon ^a,b  

^a G GENNIMATAS GENERAL HOSPITAL   (Greece)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EVANGELISMOS HOSPITAL   (Greece)

^d UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

COLCHICINE; CREATINE KINASE MB; HIGH SENSITIVITY TROPONIN T; PLACEBO; TROPONIN T; UNCLASSIFIED DRUG; TUBULIN MODULATOR;

ADULT; AGED; ARTICLE; COHORT ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; DIARRHEA; DRUG WITHDRAWAL; EUROSCORE; EXTRACORPOREAL CIRCULATION; FEMALE; HEART MUSCLE INJURY; HUMAN; MAJOR CLINICAL STUDY; MALE; ON PUMP CORONARY ARTERY BYPASS GRAFTING; OUTCOME ASSESSMENT; PATIENT COMPLIANCE; PERIOPERATIVE PERIOD; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION; ACUTE CORONARY SYNDROME; ADVERSE EFFECTS; BLOOD; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; FOLLOW UP; GREECE; HEART MUSCLE; INCIDENCE; METABOLISM; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; PROCEDURES; TREATMENT OUTCOME;

ACUTE CORONARY SYNDROME; AGED; COLCHICINE; CORONARY ARTERY BYPASS; CREATINE KINASE, MB FORM; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; GREECE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MYOCARDIUM; PERIOPERATIVE CARE; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES; TREATMENT OUTCOME; TROPONIN T; TUBULIN MODULATORS;

EID: 84928584626     PISSN: 00029149     EISSN: 18791913     Source Type: Journal    
DOI: 10.1016/j.amjcard.2015.02.036     Document Type: Article

References (30)

1. E.M. Boyle, T.H. Pohlman, M.C. Johnson, and E.D. Verrier Endothelial cell injury in cardiovascular surgery: the systemic inflammatory response Ann Thorac Surg 63 1997 277 284
2. B.E. Miller, and J.H. Levy The inflammatory response to cardiopulmonary bypass J Cardiothorac Vasc Anesth 11 1997 355 366
3. M.A. Costa, R.G. Carere, S.V. Lichtenstein, D.P. Foley, V. de Valk, W. Lindenboom, P.C. Roose, T.R. van Geldorp, C. Macaya, J.L. Castanon, F. Fernandez-Avilèz, J.H. Gonzáles, G. Heyer, F. Unger, and P.W. Serruys Incidence, predictors, and significance of abnormal cardiac enzyme rise in patients treated with bypass surgery in the arterial revascularization therapies study (ARTS) Circulation 104 2001 2689 2693
4. K. Klatte, B.R. Chaitman, P. Theroux, J.A. Gavard, K. Stocke, S. Boyce, C. Bartels, B. Keller, and A. Jessel GUARDIAN Investigators. Increased mortality after coronary artery bypass graft surgery is associated with increased levels of postoperative creatine kinase-myocardial band isoenzyme release: results from the GUARDIAN trial J Am Coll Cardiol 38 2001 1070 1077
5. B.L. Croal, G.S. Hillis, P.H. Gibson, M.T. Fazal, H. El-Shafei, G. Gibson, R.R. Jeffrey, K.G. Buchan, D. West, and B.H. Cuthbertson Relationship between postoperative cardiac troponin I levels and outcome of cardiac surgery Circulation 114 2006 1468 1475
6. J.L. Januzzi, K. Lewandrowski, T.E. MacGillivray, J.B. Newell, S. Kathiresan, S.J. Servoss, and E. Lee-Lewandrowski A comparison of cardiac troponin T and creatine kinase-MB for patient evaluation after cardiac surgery J Am Coll Cardiol 39 2002 1518 1523
7. D. Paparella, G. Cappabianca, G. Visicchio, A. Galeone, A. Marzovillo, N. Gallo, C. Memmola, and L. Schinosa Lde Cardiac troponin I release after coronary artery bypass grafting operation: effects on operative and midterm survival Ann Thorac Surg 80 2005 1758 1764
8. G.A. Lurati Buse, D. Bolliger, E. Seeberger, J. Kasper, M. Grapow, M.T. Koller, M.D. Seeberger, and M. Filipovic Troponin T and brain natriuretic peptide after on-pump cardiac surgery: prognostic impact on 12-month mortality and major cardiac events after adjustment for postoperative complications Circulation 130 2014 948 957
9. C.C. Lim, F. Cuculi, W.J. van Gaal, L. Testa, J.R. Arnold, T. Karamitsos, J.M. Francis, J.E. Digby, C. Antoniades, R.K. Kharbanda, S. Neubauer, S. Westaby, and A.P. Banning Early diagnosis of perioperative myocardial infarction after coronary bypass grafting: a study using biomarkers and cardiac magnetic resonance imaging Ann Thorac Surg 92 2011 2046 2053
10. U. Jain Myocardial infarction during coronary artery bypass surgery J Cardiothorac Vasc Anesth 6 1992 612 623
11. C. Rasmussen, J.J. Thiis, P. Clemmensen, F. Efsen, H.C. Arendrup, K. Saunamäki, J.K. Madsen, and G. Pettersson Significance and management of early graft failure after coronary artery bypass grafting: feasibility and results of acute angiography and re-vascularization Eur J Cardiothorac Surg 12 1997 847 852
12. J. Butler, G.M. Rocker, and S. Westaby Inflammatory response to cardiopulmonary bypass Ann Thorac Surg 55 1993 552 559
13. R. Ascione, C.T. Lloyd, M.J. Underwood, A.A. Lotto, A.A. Pitsis, and G.D. Angelini Inflammatory response after coronary revascularization with or without cardiopulmonary bypass Ann Thorac Surg 69 2000 1198 1204
14. S.G. Raja, and G.D. Dreyfus Modulation of systemic inflammatory response after cardiac surgery Asian Cardiovasc Thorac Ann 13 2005 382 395
15. S. Deftereos, G. Giannopoulos, K. Raisakis, C. Kossyvakis, A. Kaoukis, V. Panagopoulou, M. Driva, G. Hahalis, V. Pyrgakis, D. Alexopoulos, A.S. Manolis, C. Stefanadis, and M.W. Cleman Colchicine treatment for the prevention of bare-metal stent restenosis in diabetic patients J Am Coll Cardiol 61 2013 1679 1685
16. S.M. Nidorf, J.W. Eikelboom, C.A. Budgeon, and P.L. Thompson Low-dose colchicine for secondary prevention of cardiovascular disease J Am Coll Cardiol 61 2013 404 410
17. S. Deftereos, G. Giannopoulos, V. Panagopoulou, G. Bouras, K. Raisakis, C. Kossyvakis, S. Karageorgiou, C. Papadimitriou, M. Vastaki, A. Kaoukis, C. Angelidis, S. Pagoni, V. Pyrgakis, D. Alexopoulos, A.S. Manolis, C. Stefanadis, and M.W. Cleman Anti-inflammatory treatment with colchicine in stable chronic heart failure: a prospective, randomized study J Am Coll Cardiol Heart Fail 2 2014 131 137
18. S. Deftereos, G. Giannopoulos, M. Efremidis, C. Kossyvakis, A. Katsivas, V. Panagopoulou, C. Papadimitriou, S. Karageorgiou, K. Doudoumis, K. Raisakis, A. Kaoukis, D. Alexopoulos, A.S. Manolis, C. Stefanadis, and M.W. Cleman Colchicine for prevention of atrial fibrillation recurrence after pulmonary vein isolation: mid-term efficacy and effect on quality of life Heart Rhythm 11 2014 620 628
19. S. Deftereos, G. Giannopoulos, N. Papoutsidakis, V. Panagopoulou, C. Kossyvakis, K. Raisakis, M.W. Cleman, and C. Stefanadis Colchicine and the heart: pushing the envelope J Am Coll Cardiol 62 2013 1817 1825
20. R.A. Terkeltaub Colchicine update: 2008 Semin Arthritis Rheum 38 2009 411 419
21. F. Fernandes, F.J. Ramires, B.M. Ianni, V.M. Salemi, A.M. Oliveira, F.G. Pessoa, M. Canzian, and C. Mady Effect of colchicine on myocardial injury induced by Trypanosoma cruzi in experimental Chagas disease J Card Fail 18 2012 654 659
22. B.N. Cronstein, Y. Molad, J. Reibman, E. Balakhane, R.I. Levin, and G. Weissmann Colchicine alters the quantitative and qualitative display of selectins on endothelial cells and neutrophils J Clin Invest 96 1995 994 1002
23. R. Forrat, L. Sebbag, R. Ferrera, G. Hadour, E. Canet, A. Tabib, and M. de Lorgeril Effect of colchicine on circulating and myocardial neutrophils and on infarct size in a canine model of ischemia and reperfusion J Cardiovasc Pharmacol 27 1996 876 883
24. J. Vinten-Johansen Involvement of neutrophils in the pathogenesis of lethal myocardial reperfusion injury Cardiovasc Res 61 2004 481 497
25. E. Ben-Chetrit, S. Bergmann, and R. Sood Mechanism of the anti-inflammatory effect of colchicine in rheumatic diseases: a possible new outlook through microarray analysis Rheumatology (Oxford) 45 2006 274 282
26. T. Misawa, M. Takahama, T. Kozaki, H. Lee, J. Zou, T. Saitoh, and S. Akira Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome Nat Immunol 14 2013 454 460
27. M. Kawaguchi, M. Takahashi, T. Hata, Y. Kashima, F. Usui, H. Morimoto, A. Izawa, Y. Takahashi, J. Masumoto, J. Koyama, M. Hongo, T. Noda, J. Nakayama, J. Sagara, S. Taniguchi, and U. Ikeda Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury Circulation 123 2011 594 604
28. M. Imazio, R. Trinchero, A. Brucato, M.E. Rovere, A. Gandino, R. Cemin, S. Ferrua, S. Maestroni, E. Zingarelli, A. Barosi, C. Simon, F. Sansone, D. Patrini, E. Vitali, P. Ferrazzi, D.H. Spodick, Y. Adler COPPS Investigators Colchicine for the Prevention of the Post-pericardiotomy Syndrome (COPPS): a multicentre, randomized, double-blind, placebo-controlled trial Eur Heart J 31 2010 2749 2754
29. M. Imazio, A. Brucato, P. Ferrazzi, M.E. Rovere, A. Gandino, R. Cemin, S. Ferrua, R. Belli, S. Maestroni, C. Simon, E. Zingarelli, A. Barosi, F. Sansone, D. Patrini, E. Vitali, R. Trinchero, D.H. Spodick, Y. Adler COPPS Investigators Colchicine reduces postoperative atrial fibrillation: results of the Colchicine for the Prevention of the Postpericardiotomy Syndrome (COPPS) atrial fibrillation substudy Circulation 124 2011 2290 2295
30. M. Imazio, A. Brucato, P. Ferrazzi, A. Pullara, Y. Adler, A. Barosi, A.L. Caforio, R. Cemin, F. Chirillo, C. Comoglio, D. Cugola, D. Cumetti, O. Dyrda, S. Ferrua, Y. Finkelstein, R. Flocco, A. Gandino, B. Hoit, F. Innocente, S. Maestroni, F. Musumeci, J. Oh, A. Pergolini, V. Polizzi, A. Ristic, C. Simon, D.H. Spodick, V. Tarzia, S. Trimboli, A. Valenti, R. Belli, F. Gaita COPPS-2 Investigators Colchicine for prevention of postpericardiotomy syndrome and postoperative atrial fibrillation: the COPPS-2 randomized clinical trial JAMA 312 2014 1016 1023