Intra- and inter-generic transfer of pathogenicity island-encoded virulence genes by cos phages

ISME Journal

Volumn 9, Issue 5, 2015, Pages 1260-1263

  Chen, John ^a   Carpena, Nuria ^b,c   Quiles Puchalt, Nuria ^c,d   Ram, Geeta ^a   Novick, Richard P ^a   Penadés, José R ^c  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d UNIVERSIDAD CEU CARDENAL HERRERA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GENE TRANSFER; PATHOGENICITY; VIRULENCE;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS;

INTEGRASE; MITOMYCIN; VIRULENCE FACTOR;

CHEMISTRY; GENE TRANSFER; GENETICS; GENOMIC ISLAND; METABOLISM; OPEN READING FRAME; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS PHAGE; VIROLOGY; VIRULENCE;

GENE TRANSFER TECHNIQUES; GENOMIC ISLANDS; INTEGRASES; MITOMYCIN; OPEN READING FRAMES; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS PHAGES; VIRULENCE; VIRULENCE FACTORS;

EID: 84928582552     PISSN: 17517362     EISSN: 17517370     Source Type: Journal    
DOI: 10.1038/ismej.2014.187     Document Type: Article

References (13)

1. Chen J, Novick RP. (2009). Phage-mediated intergeneric transfer of toxin genes. Science 323: 139-141
2. Maiques E, Ubeda C, Tormo MA, Ferrer MD, Lasa I, Novick RP et al. (2007). Role of staphylococcal phage and SaPI integrase in intra- and interspecies SaPI transfer. J Bacteriol 189: 5608-5616
3. Novick RP, Christie GE, Penadés JR. (2010). The phage-related chromosomal islands of Gram-positive bacteria. Nat Rev Microbiol 8: 541-551
4. Quiles-Puchalt N, Carpena N, Alonso JC, Novick RP, Marina A, Penadés JR.(2014). Staphylococcal pathogenicity island DNA packaging system involving cos-site packaging and phage-encoded HNH endonucleases. Proc Natl Acad Sci USA 111: 6016-6021
5. Rao VB, Feiss M. (2008). The bacteriophage DNA packaging motor. Annu Rev Genet 42: 647-681
6. Ruzin A, Lindsay J, Novick RP. (2001). Molecular genetics of SaPI1-A mobile pathogenicity island in Staphylococcus aureus. Mol Microbiol 41: 365-377
7. Tormo-Más MÁ , Donderis J, García-Caballer M, Alt A, Mir-Sanchis I, Marina A et al. (2013). Phage dUTPases control transfer of virulence genes by a proto-oncogenic G protein-like mechanism. Mol Cell 49: 947-958
8. Tormo-Más MÁ , Mir I, Shrestha A, Tallent SM, Campoy S, Lasa I et al. (2010). Moonlighting bacteriophage proteins derepress staphylococcal pathogenicity islands. Nature 465: 779-782
9. Ubeda C, Maiques E, Barry P, Matthews A, Tormo MA, Lasa I et al. (2008). SaPI mutations affecting replication and transfer and enabling autonomous replication in the absence of helper phage. Mol Microbiol 67: 493-503
10. Ubeda C, Maiques E, Tormo MA, Campoy S, Lasa I, Barbé J et al. (2007). SaPI operon I is required for SaPI packaging and is controlled by LexA. Mol Microbiol 65: 41-50
11. Uchiyama J, Takemura-Uchiyama I, Sakaguchi Y, Gamoh K, Kato S-I, Daibata M et al. (2014). Intragenus generalized transduction in Staphylococcus spp. by a novel giant phage. ISME J 8: 1949-1952
12. Viana D, Blanco J, Tormo-Más MÁ , Selva L, Guinane CM, Baselga R et al. (2010). Adaptation of Staphylococcus aureus to ruminant and equine hosts involves SaPI-carried variants of von Willebrand factor-binding protein. Mol Microbiol 77: 1583-1594
13. Winstel V, Liang C, Sanchez-Carballo P, Steglich M, Munar M, Bröker BM et al. (2013). Wall teichoic acid structure governs horizontal gene transfer between major bacterial pathogens. Nat Commun 4: 2345