Ionizing radiation-induced cell death is partly caused by increase of mitochondrial reactive oxygen species in normal human fibroblast cells

Radiation Research

Volumn 183, Issue 4, 2015, Pages 455-464

  Kobashigawa, Shinko ^a   Kashino, Genro ^a   Suzuki, Keiji ^b   Yamashita, Shunichi ^b   Mori, Hiromu ^a  

^a OITA UNIVERSITY   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 GLUCOPYRANOSIDE ASCORBIC ACID; ANTIOXIDANT; CELL NUCLEUS DNA; CELL PROTEIN; DOUBLE STRANDED DNA; HISTONE H2AX; PROTEIN DRP1; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; ASCORBIC ACID; ASCORBIC ACID 2-O-GLUCOSIDE; DNM1L PROTEIN, HUMAN; GUANOSINE TRIPHOSPHATASE; MICROTUBULE ASSOCIATED PROTEIN; MITOCHONDRIAL PROTEIN;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; DNA STRAND BREAKAGE; FIBROBLAST; GAMMA RADIATION; HUMAN; HUMAN CELL; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PREPUCE; PRIORITY JOURNAL; RADIOSENSITIVITY; ANALOGS AND DERIVATIVES; CYTOLOGY; DEFICIENCY; DOUBLE STRANDED DNA BREAK; DRUG EFFECTS; GENE SILENCING; GENETICS; METABOLISM; MITOCHONDRION; PROTEIN TRANSPORT; RADIATION DOSE; RADIATION RESPONSE; TIME;

ANTIOXIDANTS; ASCORBIC ACID; CELL DEATH; DNA BREAKS, DOUBLE-STRANDED; DOSE-RESPONSE RELATIONSHIP, RADIATION; FIBROBLASTS; GENE KNOCKDOWN TECHNIQUES; GTP PHOSPHOHYDROLASES; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PROTEIN TRANSPORT; RADIATION TOLERANCE; REACTIVE OXYGEN SPECIES; TIME FACTORS;

EID: 84928561337     PISSN: 00337587     EISSN: 19385404     Source Type: Journal    
DOI: 10.1667/RR13772.1     Document Type: Article

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