Aberrant TCRδ rearrangement underlies the T-cell lymphocytopenia and t(12;14) translocation associated with ATM deficiency

Blood

Volumn 125, Issue 17, 2015, Pages 2665-2668

  Jiang, Wenxia ^a,b   Lee, Brian J ^a,b   Li, Chen ^a,b   Dubois, Richard L ^a,b   Gostissa, Monica ^c   Alt, Frederick W ^c   Zha, Shan ^a,b  

^a Institute for Cancer Genetics   (United States)

^b Department of Medicine   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN H; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR DELTA CHAIN; UNCLASSIFIED DRUG; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER PATIENT; CANCER RISK; CHROMOSOME INVERSION; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DISEASE SEVERITY; DNA DAMAGE; ENHANCER REGION; GENE LOCUS; GENE REARRANGEMENT; GENETIC STABILITY; LYMPHOCYTOPENIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOMATIC MUTATION; T CELL LEUKEMIA; T CELL LYMPHOMA; THYMUS LYMPHOMA; VDJ RECOMBINATION; AMINO ACID SEQUENCE; ANIMAL; ATAXIA TELANGIECTASIA; CHROMOSOME 14; COMPLICATION; GENE DELETION; GENE TRANSLOCATION; GENETICS; GENOMIC INSTABILITY; HUMAN; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; ATAXIA TELANGIECTASIA; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CHROMOSOMES, HUMAN, PAIR 14; GENE DELETION; GENOMIC INSTABILITY; HUMANS; LYMPHOMA, T-CELL; LYMPHOPENIA; MICE; MOLECULAR SEQUENCE DATA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTES; TRANSLOCATION, GENETIC; V(D)J RECOMBINATION;

EID: 84928473238     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2015-01-622621     Document Type: Article

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