Epigenetic determinants of CYP1A1 induction by the aryl hydrocarbon receptor agonist 3,3′,4,4′,5-pentachlorobiphenyl (PCB 126)

International Journal of Molecular Sciences

Volumn 15, Issue 8, 2014, Pages 13916-13931

  Vorrink, Sabine U ^a,b   Hudachek, Danielle R ^a,b   Domann, Frederick E ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Aryl hydrocarbon receptor; Chromatin accessibility; DNA methylation; Epigenetic regulation; Polychlorinated biphenyls

Indexed keywords

3, 3', 4, 4', 5 PENTACHLOROBIPHENYL; 5 AZA 2' DEOXYCYTIDINE; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A1; HYPOXIA INDUCIBLE FACTOR 1BETA; MESSENGER RNA; POLYCHLORINATED BIPHENYL; TRICHOSTATIN A; UNCLASSIFIED DRUG; 3,4,5,3',4'-PENTACHLOROBIPHENYL; AZACITIDINE; CHROMATIN; DECITABINE; HYDROXAMIC ACID;

ARTICLE; CENTRIFUGATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; EPIGENETICS; HELA CELL LINE; HEPG2 CELL LINE; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INDUCTION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; AGONISTS; ANALOGS AND DERIVATIVES; CHEMISTRY; CHROMATIN; DRUG EFFECTS; GENETIC EPIGENESIS; GENETICS; METABOLISM;

ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; AZACITIDINE; CHROMATIN; CPG ISLANDS; CYTOCHROME P-450 CYP1A1; DNA METHYLATION; EPIGENESIS, GENETIC; HELA CELLS; HEP G2 CELLS; HUMANS; HYDROXAMIC ACIDS; POLYCHLORINATED BIPHENYLS; PROMOTER REGIONS, GENETIC; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER;

EID: 84928467911     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150813916     Document Type: Article

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