-
1
-
-
33646755569
-
Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity
-
Smyth MJ, Dunn GP, Schreiber RD. Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity. Adv Immunol 2006;90:1-50.
-
(2006)
Adv Immunol
, vol.90
, pp. 1-50
-
-
Smyth, M.J.1
Dunn, G.P.2
Schreiber, R.D.3
-
2
-
-
34248193253
-
Immune surveillance of tumors
-
Swann JB, Smyth MJ. Immune surveillance of tumors. J Clin Invest 2007;117:1137-46.
-
(2007)
J Clin Invest
, vol.117
, pp. 1137-1146
-
-
Swann, J.B.1
Smyth, M.J.2
-
3
-
-
84876758617
-
Metabolic pathways in immune cell activation and quiescence
-
Pearce EL, Pearce EJ. Metabolic pathways in immune cell activation and quiescence. Immunity 2013;38:633-43.
-
(2013)
Immunity
, vol.38
, pp. 633-643
-
-
Pearce, E.L.1
Pearce, E.J.2
-
4
-
-
44449118921
-
Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets
-
Furuhashi M, Hotamisligil GS. Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets. Nat Rev Drug Discov 2008;7:489-503.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 489-503
-
-
Furuhashi, M.1
Hotamisligil, G.S.2
-
5
-
-
0043253165
-
The mammalian fatty acidbinding protein multigene family: molecular and genetic insights into function
-
Hertzel AV, Bernlohr DA. The mammalian fatty acidbinding protein multigene family: molecular and genetic insights into function. Trends Endocrinol Metab 2000;11:175-80.
-
(2000)
Trends Endocrinol Metab
, vol.11
, pp. 175-180
-
-
Hertzel, A.V.1
Bernlohr, D.A.2
-
6
-
-
50949128339
-
The emerging functions and mechanisms of mammalian fatty acid-binding proteins
-
Storch J, Corsico B. The emerging functions and mechanisms of mammalian fatty acid-binding proteins. Annu Rev Nutr 2008;28:73-95.
-
(2008)
Annu Rev Nutr
, vol.28
, pp. 73-95
-
-
Storch, J.1
Corsico, B.2
-
7
-
-
84928387843
-
E-FABP: regulator of immune function
-
Zhang Y, Li B. E-FABP: regulator of immune function. Oncoscience 2014;1:398-9.
-
(2014)
Oncoscience
, vol.1
, pp. 398-399
-
-
Zhang, Y.1
Li, B.2
-
8
-
-
84902144284
-
Fatty acid-binding protein E-FABP restricts tumor growth by promoting IFN-beta responses in tumor-associated macrophages
-
Zhang Y, Sun Y, Rao E, Yan F, Li Q, Zhang Y, et al. Fatty acid-binding protein E-FABP restricts tumor growth by promoting IFN-beta responses in tumor-associated macrophages. Cancer Res 2014;74:2986-98.
-
(2014)
Cancer Res
, vol.74
, pp. 2986-2998
-
-
Zhang, Y.1
Sun, Y.2
Rao, E.3
Yan, F.4
Li, Q.5
Zhang, Y.6
-
9
-
-
67649184778
-
Regulation of Th17 differentiation by epidermal fatty acidbinding protein
-
Li B, Reynolds JM, Stout RD, Bernlohr DA, Suttles J. Regulation of Th17 differentiation by epidermal fatty acidbinding protein. J Immunol 2009;182:7625-33.
-
(2009)
J Immunol
, vol.182
, pp. 7625-7633
-
-
Li, B.1
Reynolds, J.M.2
Stout, R.D.3
Bernlohr, D.A.4
Suttles, J.5
-
10
-
-
70349649220
-
Identification and characterization of a small molecule inhibitor of Fatty Acid binding proteins
-
Hertzel AV, Hellberg K, Reynolds JM, Kruse AC, Juhlmann BE, Smith AJ, et al. Identification and characterization of a small molecule inhibitor of Fatty Acid binding proteins. J Med Chem 2009;52:6024-31.
-
(2009)
J Med Chem
, vol.52
, pp. 6024-6031
-
-
Hertzel, A.V.1
Hellberg, K.2
Reynolds, J.M.3
Kruse, A.C.4
Juhlmann, B.E.5
Smith, A.J.6
-
11
-
-
3843057021
-
Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target
-
Lehmann F, Haile S, Axen E, Medina C, Uppenberg J, Svensson S, et al. Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target. Bioorg Med Chem Lett 2004;14:4445-8.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, pp. 4445-4448
-
-
Lehmann, F.1
Haile, S.2
Axen, E.3
Medina, C.4
Uppenberg, J.5
Svensson, S.6
-
12
-
-
79955561585
-
New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein
-
Liu X, Huang X, Lin W, Wang D, Diao Y, Li H, et al. New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein. Bioorg Med Chem Lett 2011;21:2949-52.
-
(2011)
Bioorg Med Chem Lett
, vol.21
, pp. 2949-2952
-
-
Liu, X.1
Huang, X.2
Lin, W.3
Wang, D.4
Diao, Y.5
Li, H.6
-
13
-
-
34249727188
-
Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP)
-
Sulsky R, Magnin DR, Huang Y, Simpkins L, Taunk P, Patel M, et al. Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP). Bioorg Med Chem Lett 2007;17:3511-5.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, pp. 3511-3515
-
-
Sulsky, R.1
Magnin, D.R.2
Huang, Y.3
Simpkins, L.4
Taunk, P.5
Patel, M.6
-
14
-
-
34250904186
-
Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2
-
Furuhashi M, Tuncman G, Gorgun CZ, Makowski L, Atsumi G, Vaillancourt E, et al. Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2. Nature 2007;447:959-65.
-
(2007)
Nature
, vol.447
, pp. 959-965
-
-
Furuhashi, M.1
Tuncman, G.2
Gorgun, C.Z.3
Makowski, L.4
Atsumi, G.5
Vaillancourt, E.6
-
15
-
-
12144289984
-
Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy
-
Friesner RA, Banks JL, Murphy RB, Halgren TA, Klicic JJ, Mainz DT, et al. Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy. J Med Chem 2004;47:1739-49.
-
(2004)
J Med Chem
, vol.47
, pp. 1739-1749
-
-
Friesner, R.A.1
Banks, J.L.2
Murphy, R.B.3
Halgren, T.A.4
Klicic, J.J.5
Mainz, D.T.6
-
16
-
-
84894114973
-
Crystallographic study of FABP5 as an intracellular endocannabinoid transporter
-
Sanson B, Wang T, Sun J, Wang L, Kaczocha M, Ojima I, et al. Crystallographic study of FABP5 as an intracellular endocannabinoid transporter. Acta Crystallogr D Biol Crystallogr 2014;70:290-8.
-
(2014)
Acta Crystallogr D Biol Crystallogr
, vol.70
, pp. 290-298
-
-
Sanson, B.1
Wang, T.2
Sun, J.3
Wang, L.4
Kaczocha, M.5
Ojima, I.6
-
17
-
-
84873682648
-
Immunology. Sensing the dark side of DNA
-
O'Neill LA. Immunology. Sensing the dark side of DNA. Science 2013;339:763-4.
-
(2013)
Science
, vol.339
, pp. 763-764
-
-
O'Neill, L.A.1
-
18
-
-
84859417315
-
Type I IFN drives a distinctive dendritic cell maturation phenotype that allows continued class II MHC synthesis and antigen processing
-
Simmons DP, Wearsch PA, Canaday DH, Meyerson HJ, Liu YC, Wang Y, et al. Type I IFN drives a distinctive dendritic cell maturation phenotype that allows continued class II MHC synthesis and antigen processing. J Immunol 2012;188:3116-26.
-
(2012)
J Immunol
, vol.188
, pp. 3116-3126
-
-
Simmons, D.P.1
Wearsch, P.A.2
Canaday, D.H.3
Meyerson, H.J.4
Liu, Y.C.5
Wang, Y.6
-
19
-
-
22144444216
-
Type I interferon and cancer immunoediting
-
Smyth MJ. Type I interferon and cancer immunoediting. Nat Immunol 2005;6:646-8.
-
(2005)
Nat Immunol
, vol.6
, pp. 646-648
-
-
Smyth, M.J.1
-
20
-
-
84879292234
-
Discovery of the novel mTOR inhibitor and its antitumor activities in vitro and in vivo
-
Xie H, Lee MH, Zhu F, Reddy K, Huang Z, Kim DJ, et al. Discovery of the novel mTOR inhibitor and its antitumor activities in vitro and in vivo. Mol Cancer Ther 2013;12:950-8.
-
(2013)
Mol Cancer Ther
, vol.12
, pp. 950-958
-
-
Xie, H.1
Lee, M.H.2
Zhu, F.3
Reddy, K.4
Huang, Z.5
Kim, D.J.6
-
21
-
-
79953142333
-
Peroxisome proliferator-activated receptor gamma negatively regulates IFN-beta production in Toll-like receptor (TLR) 3-and TLR4-stimulated macrophages by preventing interferon regulatory factor 3 binding to the IFNbeta promoter
-
Zhao W, Wang L, Zhang M, Wang P, Zhang L, Yuan C, et al. Peroxisome proliferator-activated receptor gamma negatively regulates IFN-beta production in Toll-like receptor (TLR) 3-and TLR4-stimulated macrophages by preventing interferon regulatory factor 3 binding to the IFNbeta promoter. J Biol Chem 2011;286:5519-28.
-
(2011)
J Biol Chem
, vol.286
, pp. 5519-5528
-
-
Zhao, W.1
Wang, L.2
Zhang, M.3
Wang, P.4
Zhang, L.5
Yuan, C.6
-
22
-
-
77956866143
-
Involvement of Fatty Acid Binding Protein 5 and PPARbeta/delta in Prostate Cancer Cell Growth
-
Morgan E, Kannan-Thulasiraman P, Noy N. Involvement of Fatty Acid Binding Protein 5 and PPARbeta/delta in Prostate Cancer Cell Growth. PPAR Res 2010;2010.
-
(2010)
PPAR Res 2010
-
-
Morgan, E.1
Kannan-Thulasiraman, P.2
Noy, N.3
-
23
-
-
77957745555
-
Type I interferon: friend or foe?
-
Trinchieri G. Type I interferon: friend or foe?. J Exp Med 2010;207:2053-63.
-
(2010)
J Exp Med
, vol.207
, pp. 2053-2063
-
-
Trinchieri, G.1
-
24
-
-
34548126503
-
Present role and future potential of type I interferons in adjuvant therapy of highrisk operable melanoma
-
Moschos S, Kirkwood JM. Present role and future potential of type I interferons in adjuvant therapy of highrisk operable melanoma. Cytokine Growth Factor Rev 2007;18:451-8.
-
(2007)
Cytokine Growth Factor Rev
, vol.18
, pp. 451-458
-
-
Moschos, S.1
Kirkwood, J.M.2
-
25
-
-
0036005887
-
Endogenous type I interferons as a defense against tumors
-
Gresser I, Belardelli F. Endogenous type I interferons as a defense against tumors. Cytokine Growth Factor Rev 2002;13:111-8.
-
(2002)
Cytokine Growth Factor Rev
, vol.13
, pp. 111-118
-
-
Gresser, I.1
Belardelli, F.2
-
26
-
-
80355147292
-
Type I interferon is selectively required by dendritic cells for immune rejection of tumors
-
Diamond MS, Kinder M, Matsushita H, Mashayekhi M, Dunn GP, Archambault JM, et al. Type I interferon is selectively required by dendritic cells for immune rejection of tumors. J Exp Med 2011;208:1989-2003.
-
(2011)
J Exp Med
, vol.208
, pp. 1989-2003
-
-
Diamond, M.S.1
Kinder, M.2
Matsushita, H.3
Mashayekhi, M.4
Dunn, G.P.5
Archambault, J.M.6
-
27
-
-
77957745555
-
Type I interferon: friend or foe?
-
Trinchieri G. Type I interferon: friend or foe? J Exp Med 2010;207:2053-63.
-
(2010)
J Exp Med
, vol.207
, pp. 2053-2063
-
-
Trinchieri, G.1
-
28
-
-
84904173553
-
Metabolism of stromal and immune cells in health and disease
-
Ghesquiere B, Wong BW, Kuchnio A, Carmeliet P. Metabolism of stromal and immune cells in health and disease. Nature 2014;511:167-76.
-
(2014)
Nature
, vol.511
, pp. 167-176
-
-
Ghesquiere, B.1
Wong, B.W.2
Kuchnio, A.3
Carmeliet, P.4
-
29
-
-
84859464555
-
Orchestration of metabolism by macrophages
-
Biswas SK, Mantovani A. Orchestration of metabolism by macrophages. Cell Metab 2012;15:432-7.
-
(2012)
Cell Metab
, vol.15
, pp. 432-437
-
-
Biswas, S.K.1
Mantovani, A.2
-
30
-
-
33751565434
-
Regulation of dendritic cell function and T cell priming by the fatty acid-binding protein AP2
-
Rolph MS, Young TR, Shum BO, Gorgun CZ, Schmitz-Peiffer C, Ramshaw IA, et al. Regulation of dendritic cell function and T cell priming by the fatty acid-binding protein AP2. J Immunol 2006;177:7794-801.
-
(2006)
J Immunol
, vol.177
, pp. 7794-7801
-
-
Rolph, M.S.1
Young, T.R.2
Shum, B.O.3
Gorgun, C.Z.4
Schmitz-Peiffer, C.5
Ramshaw, I.A.6
-
31
-
-
37249005205
-
The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability
-
Niesen FH, Berglund H, Vedadi M. The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability. Nat Protoc 2007;2:2212-21.
-
(2007)
Nat Protoc
, vol.2
, pp. 2212-2221
-
-
Niesen, F.H.1
Berglund, H.2
Vedadi, M.3
-
32
-
-
67649391259
-
Glycolipid acquisition by human glycolipid transfer protein dramatically alters intrinsic tryptophan fluorescence: insights into glycolipid binding affinity
-
Zhai X, Malakhova ML, Pike HM, Benson LM, Bergen HR, III, Sugar IP, et al. Glycolipid acquisition by human glycolipid transfer protein dramatically alters intrinsic tryptophan fluorescence: insights into glycolipid binding affinity. J Biol Chem 2009;284:13620-8.
-
(2009)
J Biol Chem
, vol.284
, pp. 13620-13628
-
-
Zhai, X.1
Malakhova, M.L.2
Pike, H.M.3
Benson, L.M.4
Bergen, H.R.5
Sugar, I.P.6
-
33
-
-
33846479526
-
IL-12 rapidly alters the functional profile of tumor-associated and tumor-infiltrating macrophages in vitro and in vivo
-
Watkins SK, Egilmez NK, Suttles J, Stout RD. IL-12 rapidly alters the functional profile of tumor-associated and tumor-infiltrating macrophages in vitro and in vivo. J Immunol 2007;178:1357-62.
-
(2007)
J Immunol
, vol.178
, pp. 1357-1362
-
-
Watkins, S.K.1
Egilmez, N.K.2
Suttles, J.3
Stout, R.D.4
|