From protease to decarboxylase: The molecular metamorphosis of phosphatidylserine decarboxylase

Journal of Biological Chemistry

Volumn 290, Issue 17, 2015, Pages 10972-10980

  Choi, Jae Yeon ^a   Duraisingh, Manoj T ^c   Marti, Matthias ^c   Mamoun, Choukri Ben ^b   Voelker, Dennis R ^a  

^a DEPARTMENT OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME ACTIVITY; MUTAGENESIS; PROSTHETICS; SYNTHESIS (CHEMICAL);

CONCERTED REACTIONS; ENDOPROTEOLYTIC CLEAVAGE; MUTAGENESIS EXPERIMENT; PHENYLMETHYLSULFONYL FLUORIDE; PHOSPHATIDYLETHANOLAMINE; POST-TRANSLATIONAL PROCESSING; SERINE PROTEASE INHIBITOR; SITE DIRECTED MUTAGENESIS;

AMINO ACIDS;

ASPARTIC ACID; ASPARTIC ACID 139; BENZYLSULFONYL FLUORIDE; CARBOXYLYASE; ENZYME PRECURSOR; HISTIDINE; HISTIDINE 198; HYBRID PROTEIN; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLSERINE DECARBOXYLASE; PROTEINASE; SERINE; SERINE 308; SERINE PROTEINASE; UNCLASSIFIED DRUG; PROTOZOAL PROTEIN;

ALPHA CHAIN; AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DECARBOXYLATION; ESCHERICHIA COLI; GENETIC TRANSCRIPTION; IN VITRO STUDY; METAMORPHOSIS; MUTAGENESIS; NONHUMAN; PLASMODIUM KNOWLESI; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN MOTIF; PROTEIN PROCESSING; RNA TRANSLATION; SITE DIRECTED MUTAGENESIS; ENZYMOLOGY; GENETICS; METABOLISM; PHYSIOLOGY; PROTEIN DEGRADATION; STRUCTURE ACTIVITY RELATION;

EUKARYOTA; PLASMODIUM KNOWLESI; PROKARYOTA;

AMINO ACID MOTIFS; CARBOXY-LYASES; PLASMODIUM KNOWLESI; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; PROTOZOAN PROTEINS; SERINE PROTEASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84928378285     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.642413     Document Type: Article

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